Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR217W
Length:
525
Number of sequences:
5887
Description:
YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871P58894    360   CARA_STRP8 Carbamoyl-phosphate synthase small...1820.023     40.8     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
872Q8EHS6    386   CARA_SHEON Carbamoyl-phosphate synthase small...1970.023     40.8     27     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
873P38099    384   CARA_PSEST Carbamoyl-phosphate synthase small...940.024     40.8     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
874Q8DTR1    201   HIS5_STRMU Imidazole glycerol phosphate synth...2090.025     40     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
875Q7VQW7    196   HIS5_BLOFL Imidazole glycerol phosphate synth...1280.026     39.7     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
876Q6CIQ1    409   CARA_KLULA Carbamoyl-phosphate synthase argin...1730.028     40.4     25     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.
877Q8TS91    202   HIS5_METAC Imidazole glycerol phosphate synth...1330.03     39.7     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
878Q9JP87    384   CARA_RUBGE Carbamoyl-phosphate synthase small...1770.031     40.4     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
879Q7N8W2    387   CARA_PHOLL Carbamoyl-phosphate synthase small...1800.035     40     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
880Q8FLB1    382   CARA_ECOL6 Carbamoyl-phosphate synthase small...1820.042     40     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
881P0A6F1    382   CARA_ECOLI Carbamoyl-phosphate synthase small...1820.042     40     25     42GO:0005951; C:carbamoyl-phosphate synthase complex; IDA:EcoCyc.::GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IMP:EcoliWiki.::GO:0006526; P:arginine biosynthetic process; IMP:EcoliWiki.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
882P0A6F2    382   CARA_ECO57 Carbamoyl-phosphate synthase small...1820.042     40     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
883Q8C196    1500   CPSM_MOUSE Carbamoyl-phosphate synthase [ammo...460.042     40.4     43     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IMP:MGI.
GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0000050; P:urea cycle; IC:MGI.
884P07756    1500   CPSM_RAT Carbamoyl-phosphate synthase [ammoni...460.043     40.4     43     65GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005509; F:calcium ion binding; IPI:RGD.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IDA:RGD.::GO:0004175; F:endopeptidase activity; IMP:RGD.::GO:0016595; F:glutamate binding; IPI:RGD.::GO:0005543; F:phospholipid binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.
GO:0055081; P:anion homeostasis; IDA:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:RGD.::GO:0071377; P:cellular response to glucagon stimulus; IEP:RGD.::GO:0071400; P:cellular response to oleic acid; IEP:RGD.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0070365; P:hepatocyte differentiation; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD.::GO:0000050; P:urea cycle; IDA:RGD.
885Q4FNT5    208   HIS5_PELUB Imidazole glycerol phosphate synth...1310.044     39.3     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
886Q6D408    196   HIS5_ERWCT Imidazole glycerol phosphate synth...1340.05     38.9     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
887Q5QWQ7    196   HIS5_IDILO Imidazole glycerol phosphate synth...1320.054     38.9     30     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
888A5G7Y9    273   NADE_GEOUR NH(3)-dependent NAD(+) synthetase ...1960.054     39.3     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
889O93937    2275   PYR1_EMENI Protein pyrABCN OS=194 / M139) (As...1760.055     40     26     43
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; TAS:UniProtKB.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
890Q9A231    213   HIS5_CAUCR Imidazole glycerol phosphate synth...1430.055     38.9     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
891A3CNT2    207   HIS5_STRSV Imidazole glycerol phosphate synth...2030.056     38.9     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
892Q6D0C8    382   CARA_ERWCT Carbamoyl-phosphate synthase small...2090.056     39.7     23     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
893Q3AD50    199   HIS5_CARHZ Imidazole glycerol phosphate synth...1900.06     38.9     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
894P59501    196   HIS5_BUCBP Imidazole glycerol phosphate synth...1270.061     38.5     30     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
895Q8ZY49    346   CARA_PYRAE Carbamoyl-phosphate synthase small...1750.064     39.3     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
896O25835    375   CARA_HELPY Carbamoyl-phosphate synthase small...1800.064     39.3     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
897Q7U055    376   CARA_MYCBO Carbamoyl-phosphate synthase small...1810.065     39.3     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
898Q4FPU1    214   HIS5_PSYA2 Imidazole glycerol phosphate synth...1440.065     38.9     28     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
899C5BQ30    386   CARA_TERTT Carbamoyl-phosphate synthase small...950.066     39.3     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
900Q9HNI6    218   HIS5_HALSA Imidazole glycerol phosphate synth...2270.066     38.9     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
901P71811    376   CARA_MYCTU Carbamoyl-phosphate synthase small...1810.067     39.3     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
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