UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR217W

Length:

525

Number of sequences:

5887

Description:

YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
841	Q9KSX0	203	HIS5_VIBCH Imidazole glycerol phosphate synth...	132	0.013	40.8	28	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
842	Q6GHN3	366	CARA_STAAR Carbamoyl-phosphate synthase small...	181	0.013	41.6	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
843	Q8RSS4	381	CARA_HALER Carbamoyl-phosphate synthase small...	173	0.013	41.6	25	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
844	P27708	2225	PYR1_HUMAN CAD protein OS=Homo sapiens (Human...	174	0.014	42	26	41	GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; ISS:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0043195; C:terminal button; ISS:BHF-UCL.
									GO:0070335; F:aspartate binding; ISS:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; ISS:BHF-UCL.::GO:0005524; F:ATP binding; ISS:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; ISS:BHF-UCL.::GO:0004151; F:dihydroorotase activity; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; ISS:BHF-UCL.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0017144; P:drug metabolic process; ISS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:BHF-UCL.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
845	P58789	194	HIS5_PYRFU Imidazole glycerol phosphate synth...	126	0.015	40.4	29	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
846	P20054	2225	PYR1_DICDI Protein PYR1-3 OS=Dictyostelium di...	136	0.015	42	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:dictyBase.::GO:0004151; F:dihydroorotase activity; IDA:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:dictyBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
847	Q8DEM1	379	CARA_VIBVU Carbamoyl-phosphate synthase small...	180	0.016	41.2	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
848	Q5HPY9	366	CARA_STAEQ Carbamoyl-phosphate synthase small...	181	0.016	41.2	29	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
849	Q8D8Q3	204	HIS5_VIBVU Imidazole glycerol phosphate synth...	134	0.016	40.4	27	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
850	Q7MLS3	204	HIS51_VIBVY Imidazole glycerol phosphate synt...	134	0.016	40.4	27	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
851	A8AY26	207	HIS5_STRGC Imidazole glycerol phosphate synth...	136	0.016	40.4	27	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
852	Q8XHB2	349	CARA_CLOPE Carbamoyl-phosphate synthase small...	182	0.016	41.2	27	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
853	Q6F8M7	379	CARA_ACIAD Carbamoyl-phosphate synthase small...	178	0.017	41.2	25	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
854	Q17VI1	379	CARA_HELAH Carbamoyl-phosphate synthase small...	185	0.017	41.2	26	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
855	P24773	752	TRPG_PENCH Anthranilate synthase component 2 ...	159	0.017	41.6	25	40
									GO:0004049; F:anthranilate synthase activity; IEA:EC.::GO:0004425; F:indole-3-glycerol-phosphate synthase activity; IEA:EC.::GO:0004640; F:phosphoribosylanthranilate isomerase activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
856	P63730	366	CARA_STAAW Carbamoyl-phosphate synthase small...	177	0.017	41.2	25	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
857	Q6GA11	366	CARA_STAAS Carbamoyl-phosphate synthase small...	177	0.017	41.2	25	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
858	P99147	366	CARA_STAAN Carbamoyl-phosphate synthase small...	177	0.017	41.2	25	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
859	P63729	366	CARA_STAAM Carbamoyl-phosphate synthase small...	177	0.017	41.2	25	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
860	Q5HGN0	366	CARA_STAAC Carbamoyl-phosphate synthase small...	177	0.017	41.2	25	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
861	Q7UGJ6	389	CARA_RHOBA Carbamoyl-phosphate synthase small...	174	0.017	41.2	28	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
862	O19886	399	CARA_CYACA Carbamoyl-phosphate synthase small...	185	0.017	41.2	24	41	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
863	Q58425	354	CARA_METJA Carbamoyl-phosphate synthase small...	178	0.019	41.2	25	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
864	P42388	196	TRPG_BUCAP Anthranilate synthase component 2 ...	190	0.019	40	24	42
									GO:0004049; F:anthranilate synthase activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
865	P31327	1500	CPSM_HUMAN Carbamoyl-phosphate synthase [ammo...	46	0.019	41.6	46	65	GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IMP:BHF-UCL.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
									GO:0070409; P:carbamoyl phosphate biosynthetic process; IMP:UniProtKB.::GO:0019240; P:citrulline biosynthetic process; NAS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; IMP:BHF-UCL.::GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.::GO:0046209; P:nitric oxide metabolic process; IMP:BHF-UCL.::GO:0045909; P:positive regulation of vasodilation; IMP:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.::GO:0019433; P:triglyceride catabolic process; IMP:BHF-UCL.::GO:0000050; P:urea cycle; NAS:BHF-UCL.
866	Q1IWN0	394	CARA_DEIGD Carbamoyl-phosphate synthase small...	176	0.019	41.2	26	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
867	Q9S4H8	204	HIS5_LEPIR Imidazole glycerol phosphate synth...	130	0.02	40	29	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
868	Q8XZ85	378	CARA_RALSO Carbamoyl-phosphate synthase small...	182	0.021	40.8	23	38
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
869	Q09794	2244	PYR1_SCHPO Protein ura1 OS=Schizosaccharomyce...	192	0.021	41.6	24	41	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IGI:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0004151; F:dihydroorotase activity; IGI:PomBase.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IGI:PomBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000050; P:urea cycle; IC:PomBase.
870	Q87WP3	378	CARA_PSESM Carbamoyl-phosphate synthase small...	96	0.022	40.8	32	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
871	P58894	360	CARA_STRP8 Carbamoyl-phosphate synthase small...	182	0.023	40.8	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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