UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR217W

Length:

525

Number of sequences:

5887

Description:

YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
541	Q6A6X1	530	GUAA_PROAC GMP synthase [glutamine-hydrolyzin...	521	5e-161	475	46	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
542	Q5Z1E9	524	GUAA_NOCFA GMP synthase [glutamine-hydrolyzin...	521	6e-159	470	47	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
543	B9KH18	529	GUAA_ANAMF GMP synthase [glutamine-hydrolyzin...	537	3e-158	468	48	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
544	Q5P9L5	529	GUAA_ANAMM GMP synthase [glutamine-hydrolyzin...	537	4e-158	468	48	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
545	P0A5A1	525	GUAA_MYCTU GMP synthase [glutamine-hydrolyzin...	515	6e-158	467	47	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:MTBBASE.
546	A5U871	525	GUAA_MYCTA GMP synthase [glutamine-hydrolyzin...	515	6e-158	467	47	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
547	C1AHL0	525	GUAA_MYCBT GMP synthase [glutamine-hydrolyzin...	515	6e-158	467	47	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
548	A1KP87	525	GUAA_MYCBP GMP synthase [glutamine-hydrolyzin...	515	6e-158	467	47	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
549	P0A5A2	525	GUAA_MYCBO GMP synthase [glutamine-hydrolyzin...	515	6e-158	467	47	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
550	Q4JTG0	529	GUAA_CORJK GMP synthase [glutamine-hydrolyzin...	517	3e-157	466	45	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
551	A4QBV0	523	GUAA_CORGB GMP synthase [glutamine-hydrolyzin...	517	6e-156	462	46	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
552	Q8EWS9	511	GUAA_MYCPE GMP synthase [glutamine-hydrolyzin...	522	7e-156	461	47	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
553	P60499	525	GUAA_CORDI GMP synthase [glutamine-hydrolyzin...	526	8e-156	462	45	61
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
554	C0R5H8	520	GUAA_WOLWR GMP synthase [glutamine-hydrolyzin...	534	1e-155	461	48	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
555	Q73IH1	520	GUAA_WOLPM GMP synthase [glutamine-hydrolyzin...	534	1e-155	461	48	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
556	Q5GSJ3	520	GUAA_WOLTR GMP synthase [glutamine-hydrolyzin...	535	2e-155	461	47	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
557	Q8NSR1	523	GUAA_CORGL GMP synthase [glutamine-hydrolyzin...	517	2e-155	461	46	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
558	Q7VRS2	526	GUAA_BLOFL GMP synthase [glutamine-hydrolyzin...	527	4e-154	457	45	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
559	Q8FRZ3	523	GUAA_COREF GMP synthase [glutamine-hydrolyzin...	519	4e-154	457	46	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
560	P46810	529	GUAA_MYCLE GMP synthase [glutamine-hydrolyzin...	517	6e-154	457	46	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
561	B8ZUE2	529	GUAA_MYCLB GMP synthase [glutamine-hydrolyzin...	517	6e-154	457	46	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
562	Q73U79	525	GUAA_MYCPA GMP synthase [glutamine-hydrolyzin...	515	3e-153	455	45	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
563	B3CPU7	520	GUAA_WOLPP GMP synthase [glutamine-hydrolyzin...	534	3e-153	455	47	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
564	C4Z3X1	524	GUAA_EUBE2 GMP synthase [glutamine-hydrolyzin...	529	4e-153	455	46	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
565	Q6AD51	503	GUAA_LEIXX GMP synthase [glutamine-hydrolyzin...	505	5e-153	454	46	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
566	B2HDP0	525	GUAA_MYCMM GMP synthase [glutamine-hydrolyzin...	517	2e-152	453	46	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
567	Q5HCA2	528	GUAA_EHRRW GMP synthase [glutamine-hydrolyzin...	536	7e-152	452	46	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
568	Q5FF75	528	GUAA_EHRRG GMP synthase [glutamine-hydrolyzin...	536	1e-151	451	46	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
569	Q8YBL2	507	GUAA_BRUME GMP synthase [glutamine-hydrolyzin...	492	5e-150	446	49	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
570	O52831	524	GUAA_CORAM GMP synthase [glutamine-hydrolyzin...	518	7e-149	444	46	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
571	C4ZCQ4	524	GUAA_EUBR3 GMP synthase [glutamine-hydrolyzin...	531	1e-147	441	45	63
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.

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