UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR217W

Length:

525

Number of sequences:

5887

Description:

YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
481	Q3MEA8	540	GUAA_ANAVT GMP synthase [glutamine-hydrolyzin...	521	2e-170	499	49	66
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
482	Q1LND0	539	GUAA_RALME GMP synthase [glutamine-hydrolyzin...	548	4e-170	499	48	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
483	Q3ANK7	528	GUAA_SYNSC GMP synthase [glutamine-hydrolyzin...	522	5e-170	498	49	66
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
484	Q6ASN4	528	GUAA_BORGA GMP synthase [glutamine-hydrolyzin...	515	8e-170	498	48	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
485	A1AXH0	521	GUAA_RUTMC GMP synthase [glutamine-hydrolyzin...	524	9e-170	497	47	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
486	Q5LRL6	519	GUAA_SILPO GMP synthase [glutamine-hydrolyzin...	521	2e-169	497	51	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
487	Q1LSJ1	526	GUAA_BAUCH GMP synthase [glutamine-hydrolyzin...	533	2e-169	496	47	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
488	A9AIP4	539	GUAA_BURM1 GMP synthase [glutamine-hydrolyzin...	548	2e-169	497	48	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
489	Q0AW22	510	GUAA_SYNWW GMP synthase [glutamine-hydrolyzin...	516	3e-169	496	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
490	A3NAR3	539	GUAA_BURP6 GMP synthase [glutamine-hydrolyzin...	548	3e-169	497	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
491	A3NWJ3	539	GUAA_BURP0 GMP synthase [glutamine-hydrolyzin...	548	3e-169	497	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
492	A1V534	539	GUAA_BURMS GMP synthase [glutamine-hydrolyzin...	548	3e-169	497	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
493	Q62JF6	539	GUAA_BURMA GMP synthase [glutamine-hydrolyzin...	548	3e-169	497	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
494	A2SBA7	539	GUAA_BURM9 GMP synthase [glutamine-hydrolyzin...	548	3e-169	497	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
495	A3MKQ7	539	GUAA_BURM7 GMP synthase [glutamine-hydrolyzin...	548	3e-169	497	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
496	B2J9G3	540	GUAA_NOSP7 GMP synthase [glutamine-hydrolyzin...	523	4e-169	496	48	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
497	Q254T8	512	GUAA_CHLFF GMP synthase [glutamine-hydrolyzin...	519	4e-169	495	48	67
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
498	Q63T42	547	GUAA_BURPS GMP synthase [glutamine-hydrolyzin...	550	4e-169	496	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
499	Q3JR65	547	GUAA_BURP1 GMP synthase [glutamine-hydrolyzin...	550	4e-169	496	48	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
500	B1WY30	542	GUAA_CYAA5 GMP synthase [glutamine-hydrolyzin...	523	7e-169	496	49	66
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
501	B1XLR5	540	GUAA_SYNP2 GMP synthase [glutamine-hydrolyzin...	521	9e-169	495	48	66
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
502	Q7V9A9	528	GUAA_PROMM GMP synthase [glutamine-hydrolyzin...	522	1e-168	495	49	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
503	Q470G4	539	GUAA_CUPPJ GMP synthase [glutamine-hydrolyzin...	548	2e-168	495	48	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
504	A6LD04	506	GUAA_PARD8 GMP synthase [glutamine-hydrolyzin...	517	3e-168	493	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
505	A9BER7	507	GUAA_PETMO GMP synthase [glutamine-hydrolyzin...	516	4e-168	493	48	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
506	Q73LZ4	523	GUAA_TREDE GMP synthase [glutamine-hydrolyzin...	517	8e-168	493	49	68
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
507	Q7V3N7	528	GUAA_PROMP GMP synthase [glutamine-hydrolyzin...	522	9e-168	493	48	67
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
508	B2UBD1	539	GUAA_RALPJ GMP synthase [glutamine-hydrolyzin...	548	2e-167	492	47	64
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
509	A2BTY4	528	GUAA_PROM5 GMP synthase [glutamine-hydrolyzin...	524	2e-167	492	48	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
510	Q8XZG4	547	GUAA_RALSO GMP synthase [glutamine-hydrolyzin...	548	1e-166	490	47	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
511	E4QHI6	511	GUAA_BORBN GMP synthase [glutamine-hydrolyzin...	515	1e-166	489	49	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.

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