UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR217W

Length:

525

Number of sequences:

5887

Description:

YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
361	A8Z0R1	513	GUAA_STAAT GMP synthase [glutamine-hydrolyzin...	516	3e-178	519	52	70	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
362	A6QE71	513	GUAA_STAAE GMP synthase [glutamine-hydrolyzin...	516	3e-178	519	52	70	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
363	Q5HIQ6	513	GUAA_STAAC GMP synthase [glutamine-hydrolyzin...	516	3e-178	519	52	70	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
364	Q2G0Y6	513	GUAA_STAA8 GMP synthase [glutamine-hydrolyzin...	516	3e-178	519	52	70	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
365	Q2FJM5	513	GUAA_STAA3 GMP synthase [glutamine-hydrolyzin...	516	3e-178	519	52	70	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
366	A0Q6C0	516	GUAA_FRATN GMP synthase [glutamine-hydrolyzin...	517	3e-178	519	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
367	A3DCD4	511	GUAA_CLOTH GMP synthase [glutamine-hydrolyzin...	517	3e-178	518	52	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
368	Q839J8	520	GUAA_ENTFA GMP synthase [glutamine-hydrolyzin...	516	3e-178	519	52	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
369	Q65UI1	523	GUAA_MANSM GMP synthase [glutamine-hydrolyzin...	524	4e-178	519	49	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
370	Q4L386	513	GUAA_STAHJ GMP synthase [glutamine-hydrolyzin...	516	5e-178	518	51	69	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
371	Q7WK13	530	GUAA_BORBR GMP synthase [glutamine-hydrolyzin...	537	6e-178	518	49	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
372	Q11WK3	509	GUAA_CYTH3 GMP synthase [glutamine-hydrolyzin...	517	6e-178	518	50	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
373	Q47LQ0	528	GUAA_THEFY GMP synthase [glutamine-hydrolyzin...	530	8e-178	518	49	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
374	B1YIZ1	514	GUAA_EXIS2 GMP synthase [glutamine-hydrolyzin...	515	9e-178	518	51	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
375	C0MAM2	520	GUAA_STRE4 GMP synthase [glutamine-hydrolyzin...	522	9e-178	518	52	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
376	Q0BLV0	516	GUAA_FRATO GMP synthase [glutamine-hydrolyzin...	517	1e-177	518	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
377	A7NCA3	516	GUAA_FRATF GMP synthase [glutamine-hydrolyzin...	517	1e-177	518	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
378	Q89ZV6	507	GUAA1_BACTN GMP synthase [glutamine-hydrolyzi...	517	1e-177	517	51	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
379	Q9RT91	506	GUAA_DEIRA GMP synthase [glutamine-hydrolyzin...	515	1e-177	517	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
380	Q7WAV6	530	GUAA_BORPA GMP synthase [glutamine-hydrolyzin...	537	2e-177	517	49	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
381	B9KT27	518	GUAA_RHOSK GMP synthase [glutamine-hydrolyzin...	522	2e-177	516	52	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
382	Q3J210	518	GUAA_RHOS4 GMP synthase [glutamine-hydrolyzin...	522	2e-177	516	52	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
383	Q9A7U9	520	GUAA_CAUCR GMP synthase [glutamine-hydrolyzin...	518	3e-177	516	51	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
384	B8GVI7	520	GUAA_CAUCN GMP synthase [glutamine-hydrolyzin...	518	3e-177	516	51	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
385	B0S0S7	510	GUAA_FINM2 GMP synthase [glutamine-hydrolyzin...	515	3e-177	516	50	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
386	Q7VLE9	523	GUAA_HAEDU GMP synthase [glutamine-hydrolyzin...	524	3e-177	516	49	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
387	A6SZM5	539	GUAA_JANMA GMP synthase [glutamine-hydrolyzin...	548	9e-177	516	48	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
388	Q31F66	526	GUAA_THICR GMP synthase [glutamine-hydrolyzin...	522	9e-177	515	51	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
389	Q8DZX7	520	GUAA_STRA5 GMP synthase [glutamine-hydrolyzin...	524	1e-176	515	52	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
390	Q8E5M8	520	GUAA_STRA3 GMP synthase [glutamine-hydrolyzin...	524	1e-176	515	52	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
391	Q3K1C0	520	GUAA_STRA1 GMP synthase [glutamine-hydrolyzin...	524	1e-176	515	52	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.

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