UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR217W

Length:

525

Number of sequences:

5887

Description:

YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
271	Q92SQ3	520	GUAA_RHIME GMP synthase [glutamine-hydrolyzin...	522	0	526	52	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
272	B1KLC1	525	GUAA_SHEWM GMP synthase [glutamine-hydrolyzin...	534	0	527	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
273	Q0HKV2	525	GUAA_SHESM GMP synthase [glutamine-hydrolyzin...	524	0	527	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
274	A0KUK2	525	GUAA_SHESA GMP synthase [glutamine-hydrolyzin...	524	0	527	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
275	C3LT21	517	GUAA_VIBCM GMP synthase [glutamine-hydrolyzin...	515	0	526	49	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
276	Q9KTW2	517	GUAA_VIBCH GMP synthase [glutamine-hydrolyzin...	515	0	526	49	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
277	A5F3F1	517	GUAA_VIBC3 GMP synthase [glutamine-hydrolyzin...	515	0	526	49	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
278	B7N691	525	GUAA_ECOLU GMP synthase [glutamine-hydrolyzin...	523	0	526	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
279	Q97FM9	510	GUAA_CLOAB GMP synthase [glutamine-hydrolyzin...	514	0	526	51	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
280	Q4ZX09	525	GUAA_PSEU2 GMP synthase [glutamine-hydrolyzin...	525	0	526	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
281	A5UG27	523	GUAA_HAEIG GMP synthase [glutamine-hydrolyzin...	524	0	526	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
282	B9L0W3	527	GUAA_THERP GMP synthase [glutamine-hydrolyzin...	523	0	526	50	69
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
283	B4T0N7	525	GUAA_SALNS GMP synthase [glutamine-hydrolyzin...	523	0	526	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
284	Q212S9	535	GUAA_RHOPB GMP synthase [glutamine-hydrolyzin...	526	0	526	52	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
285	Q6LU31	527	GUAA_PHOPR GMP synthase [glutamine-hydrolyzin...	530	0	526	48	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
286	Q0HX50	525	GUAA_SHESR GMP synthase [glutamine-hydrolyzin...	524	0	526	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
287	Q3JDG3	524	GUAA_NITOC GMP synthase [glutamine-hydrolyzin...	523	0	526	52	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
288	C5BLU3	525	GUAA_TERTT GMP synthase [glutamine-hydrolyzin...	523	0	526	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
289	Q89N53	551	GUAA_BRAJA GMP synthase [glutamine-hydrolyzin...	531	0	526	51	67
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
290	A1S856	525	GUAA_SHEAM GMP synthase [glutamine-hydrolyzin...	523	0	526	50	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
291	A7ZPV1	525	GUAA_ECO24 GMP synthase [glutamine-hydrolyzin...	523	0	526	48	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
292	Q48LY0	525	GUAA_PSE14 GMP synthase [glutamine-hydrolyzin...	525	0	525	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
293	B9JZA3	520	GUAA_AGRVS GMP synthase [glutamine-hydrolyzin...	522	1e-180	525	51	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
294	C5BER5	525	GUAA_EDWI9 GMP synthase [glutamine-hydrolyzin...	525	1e-180	525	49	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
295	A4WD82	525	GUAA_ENT38 GMP synthase [glutamine-hydrolyzin...	523	1e-180	525	49	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
296	A6QBI5	513	GUAA_SULNB GMP synthase [glutamine-hydrolyzin...	515	1e-180	525	51	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
297	Q32D55	525	GUAA_SHIDS GMP synthase [glutamine-hydrolyzin...	523	1e-180	525	48	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
298	A6LQ90	510	GUAA_CLOB8 GMP synthase [glutamine-hydrolyzin...	516	1e-180	525	51	70	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
299	B4EY59	525	GUAA_PROMH GMP synthase [glutamine-hydrolyzin...	525	2e-180	525	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
300	B5FAY1	517	GUAA_VIBFM GMP synthase [glutamine-hydrolyzin...	522	2e-180	525	49	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
301	Q4QNW4	523	GUAA_HAEI8 GMP synthase [glutamine-hydrolyzin...	524	2e-180	525	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.

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