UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR217W

Length:

525

Number of sequences:

5887

Description:

YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
211	A9IKK0	531	GUAA_BORPD GMP synthase [glutamine-hydrolyzin...	533	0	529	49	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
212	A8FY04	525	GUAA_SHESH GMP synthase [glutamine-hydrolyzin...	524	0	529	49	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
213	Q8UIL2	525	GUAA_AGRT5 GMP synthase [glutamine-hydrolyzin...	520	0	529	52	67	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
214	B2TXT2	525	GUAA_SHIB3 GMP synthase [glutamine-hydrolyzin...	523	0	529	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
215	A7Z235	513	GUAA_BACA2 GMP synthase [glutamine-hydrolyzin...	516	0	528	53	69
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
216	C3MCS5	520	GUAA_RHISN GMP synthase [glutamine-hydrolyzin...	522	0	529	52	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
217	Q1QKC3	540	GUAA_NITHX GMP synthase [glutamine-hydrolyzin...	526	0	529	51	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
218	Q87S07	517	GUAA_VIBPA GMP synthase [glutamine-hydrolyzin...	515	0	528	50	71
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
219	A1VEV0	515	GUAA_DESVV GMP synthase [glutamine-hydrolyzin...	516	0	528	50	68
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
220	Q72D86	515	GUAA_DESVH GMP synthase [glutamine-hydrolyzin...	516	0	528	50	68
									GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006529; P:asparagine biosynthetic process; IEA:InterPro.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
221	A5N5D9	510	GUAA_CLOK5 GMP synthase [glutamine-hydrolyzin...	516	0	528	52	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
222	B9DYY7	510	GUAA_CLOK1 GMP synthase [glutamine-hydrolyzin...	516	0	528	52	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
223	B5BAZ5	525	GUAA_SALPK GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
224	C0PYP4	525	GUAA_SALPC GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
225	A9N218	525	GUAA_SALPB GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
226	Q5PI52	525	GUAA_SALPA GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
227	Q57LJ8	525	GUAA_SALCH GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
228	Q3YZ45	525	GUAA_SHISS GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
229	Q18CT8	511	GUAA_CLOD6 GMP synthase [glutamine-hydrolyzin...	516	0	528	49	71
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
230	Q7N3K4	525	GUAA_PHOLL GMP synthase [glutamine-hydrolyzin...	525	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
231	A8AD80	525	GUAA_CITK8 GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
232	Q0T212	525	GUAA_SHIF8 GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
233	Q8ZN60	525	GUAA_SALTY GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
234	A6W2W4	525	GUAA_MARMS GMP synthase [glutamine-hydrolyzin...	523	0	528	50	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
235	Q085S4	525	GUAA_SHEFN GMP synthase [glutamine-hydrolyzin...	532	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
236	Q83QL1	525	GUAA_SHIFL GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
237	B7UGU5	525	GUAA_ECO27 GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
238	B7LKD4	525	GUAA_ESCF3 GMP synthase [glutamine-hydrolyzin...	523	0	528	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
239	Q1R8M9	525	GUAA_ECOUT GMP synthase [glutamine-hydrolyzin...	523	0	527	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
240	B1LNF9	525	GUAA_ECOSM GMP synthase [glutamine-hydrolyzin...	523	0	527	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
241	B6I579	525	GUAA_ECOSE GMP synthase [glutamine-hydrolyzin...	523	0	527	49	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.

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