Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR216C
Length:
742
Number of sequences:
5887
Description:
YMR216C SKY1 SGDID:S000004829, Chr XIII from 701039-698811, Genome Release 64-1-1, reverse complement, Verified ORF, "SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931P42525    529   ERK1_DICDI Extracellular signal-regulated kin...1611.1     36.2     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030587; P:sorocarp development; IMP:dictyBase.
932Q54L81    462   Y0700_DICDI Probable serine/threonine-protein...421.1     36.2     38     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
933Q52WX2    424   SBK1_HUMAN Serine/threonine-protein kinase SB...951.1     36.2     29     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
934E2RJI4    883   GWL_CANFA Serine/threonine-protein kinase gre...361.1     36.2     39     58GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.
935Q96GX5    879   GWL_HUMAN Serine/threonine-protein kinase gre...361.1     36.6     39     58GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IMP:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; IMP:UniProtKB.::GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.
936Q8SRU0    319   CSK2A_ENCCU Probable casein kinase II subunit...1481.1     35.8     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
937Q9BWU1    502   CDK19_HUMAN Cyclin-dependent kinase 19 OS=Hom...1651.2     36.2     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
938Q9W739    302   CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana ...1661.2     35.8     25     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
939O62618    366   MK14A_DROME Mitogen-activated protein kinase ...1481.3     35.8     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; TAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0008348; P:negative regulation of antimicrobial humoral response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0080134; P:regulation of response to stress; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0006970; P:response to osmotic stress; IDA:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
940O55173    559   PDPK1_RAT 3-phosphoinositide-dependent protei...711.3     36.2     31     51GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.
GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
941Q28GW8    652   MELK_XENTR Maternal embryonic leucine zipper ...1461.3     36.2     26     49GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
942O15530    556   PDPK1_HUMAN 3-phosphoinositide-dependent prot...711.3     36.2     28     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
943Q9LMM5    369   MPK11_ARATH Mitogen-activated protein kinase ...1601.4     35.8     28     47GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.
944P51956    506   NEK3_HUMAN Serine/threonine-protein kinase Ne...711.4     35.8     28     45GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; NAS:UniProtKB.
945Q17446    377   PMK1_CAEEL Mitogen-activated protein kinase p...1531.5     35.8     27     47GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:WormBase.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0012501; P:programmed cell death; IMP:WormBase.
946O94737    370   MAPK1_PNECA Mitogen-activated protein kinase ...1531.7     35.4     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043008; F:ATP-dependent protein binding; IPI:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0016043; P:cellular component organization; IMP:UniProtKB.::GO:0040010; P:positive regulation of growth rate; IMP:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
947Q07176    387   MMK1_MEDSA Mitogen-activated protein kinase h...1551.8     35.4     21     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000746; P:conjugation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
948P72003    476   PKNF_MYCTU Serine/threonine-protein kinase pk...661.8     35.4     35     52GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005887; C:integral to plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE.
GO:0000917; P:barrier septum assembly; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0051055; P:negative regulation of lipid biosynthetic process; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0001558; P:regulation of cell growth; IMP:MTBBASE.::GO:0010827; P:regulation of glucose transport; IMP:MTBBASE.
949Q7TZN1    476   PKNF_MYCBO Serine/threonine-protein kinase pk...661.8     35.4     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
950Q7TPS0    764   KS6A6_MOUSE Ribosomal protein S6 kinase alpha...741.8     35.8     31     49GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; IDA:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; IDA:UniProtKB.
951Q9QUK0    568   CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS...1552     35.4     25     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
952Q5MAI5    315   CDKL4_HUMAN Cyclin-dependent kinase-like 4 OS...1622.1     35     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
953P23572    297   CDK1_DROME Cyclin-dependent kinase 1 OS=Droso...1672.1     35     25     46GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IGI:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:FlyBase.::GO:0048142; P:germarium-derived cystoblast division; IMP:FlyBase.::GO:0007141; P:male meiosis I; TAS:FlyBase.::GO:0008315; P:meiotic G2/MI transition; TAS:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032880; P:regulation of protein localization; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0007284; P:spermatogonial cell division; IMP:FlyBase.
954Q05999    578   KPK7_ARATH Serine/threonine-protein kinase At...892.3     35.4     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
955Q8MXI4    419   PMK2_CAEEL Mitogen-activated protein kinase p...1762.4     35     25     46GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006950; P:response to stress; IDA:UniProtKB.
956P39951    297   CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus ...1542.5     34.7     26     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; IDA:RGD.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007569; P:cell aging; IDA:RGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0030261; P:chromosome condensation; IMP:RGD.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031100; P:organ regeneration; IMP:RGD.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0010628; P:positive regulation of gene expression; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:RGD.::GO:0006461; P:protein complex assembly; IDA:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0014075; P:response to amine stimulus; IEP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0046688; P:response to copper ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:RGD.
957P29619    292   CDKA2_ORYSJ Cyclin-dependent kinase A-2 OS=Or...1582.6     34.7     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
958Q39021    370   MPK1_ARATH Mitogen-activated protein kinase 1...1612.7     34.7     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.
GO:0009734; P:auxin mediated signaling pathway; TAS:TAIR.
959Q61846    643   MELK_MOUSE Maternal embryonic leucine zipper ...1472.7     35     27     47GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
960Q9M1Z5    393   MPK10_ARATH Mitogen-activated protein kinase ...1592.8     34.7     26     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
961Q5XIT0    507   CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R...1553     34.7     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
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