Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR208W
Length:
443
Number of sequences:
5887
Description:
YMR208W ERG12 SGDID:S000004821, Chr XIII from 684467-685798, Genome Release 64-1-1, Verified ORF, "Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P07277    443   KIME_YEAST Mevalonate kinase OS=Saccharomyces...4430     909     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IDA:SGD.
GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.::GO:0010142; P:farnesyl diphosphate biosynthetic process, mevalonate pathway; IMP:SGD.::GO:0019287; P:isopentenyl diphosphate biosynthetic process, mevalonate pathway; IMP:SGD.
2Q09780    404   KIME_SCHPO Putative mevalonate kinase OS=Schi...4049e-52     185     33     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; ISS:PomBase.::GO:0042803; F:protein homodimerization activity; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
3Q86AG7    390   KIME_DICDI Mevalonate kinase OS=Dictyostelium...4021e-49     179     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; ISS:dictyBase.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
4Q03426    396   KIME_HUMAN Mevalonate kinase OS=Homo sapiens ...4131e-47     174     32     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004496; F:mevalonate kinase activity; IDA:UniProtKB.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.::GO:0008299; P:isoprenoid biosynthetic process; IDA:UniProtKB.
5Q5E9T8    396   KIME_BOVIN Mevalonate kinase OS=Bos taurus (B...4272e-46     171     32     52GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
6P46086    378   KIME_ARATH Mevalonate kinase OS=Arabidopsis t...4035e-42     158     33     51GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IGI:TAIR.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
7Q9R008    395   KIME_MOUSE Mevalonate kinase OS=Mus musculus ...4331e-41     157     32     51GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IDA:MGI.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
8P17256    395   KIME_RAT Mevalonate kinase OS=Rattus norvegic...4234e-39     150     30     50GO:0005829; C:cytosol; IDA:RGD.::GO:0005777; C:peroxisome; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004496; F:mevalonate kinase activity; IDA:RGD.::GO:0003729; F:mRNA binding; IDA:RGD.
GO:0006695; P:cholesterol biosynthetic process; TAS:RGD.::GO:0019287; P:isopentenyl diphosphate biosynthetic process, mevalonate pathway; IDA:RGD.::GO:0017148; P:negative regulation of translation; IDA:RGD.::GO:0045540; P:regulation of cholesterol biosynthetic process; NAS:RGD.
9B6YST1    334   KIME_THEON Mevalonate kinase OS=Thermococcus ...3644e-32     129     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
10C6A3T5    333   KIME_THESM Mevalonate kinase OS=Thermococcus ...3649e-32     128     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
11C5A7L8    334   KIME_THEGJ Mevalonate kinase OS=Thermococcus ...3613e-31     126     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
12O59291    335   KIME_PYRHO Mevalonate kinase OS=NBRC 100139 /...3653e-31     126     34     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
13Q5JJC6    337   KIME_PYRKO Mevalonate kinase OS=(Thermococcus...3583e-31     126     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
14Q9V187    335   KIME_PYRAB Mevalonate kinase OS=Pyrococcus ab...3645e-31     125     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0000287; F:magnesium ion binding; IEA:HAMAP.::GO:0004496; F:mevalonate kinase activity; IEA:HAMAP.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
15Q8U0F3    334   KIME_PYRFU Mevalonate kinase OS=Pyrococcus fu...3682e-30     124     32     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
16Q58487    312   KIME_METJA Mevalonate kinase OS=JCM 10045 / N...3650.00000000001     68.9     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
17Q50559    303   KIME_METTH Mevalonate kinase OS=thermoautotro...3460.000000003     61.6     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
18Q9Y946    324   KIME_AERPE Mevalonate kinase OS=100138 / K1)....3870.000000004     61.6     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
19O27995    284   KIME_ARCFU Mevalonate kinase OS=9628 / NBRC 1...390.029     40     44     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004496; F:mevalonate kinase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
20P56838    350   GAL1_THEMA Galactokinase OS=Thermotoga mariti...1880.021     40.4     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
21Q97EZ6    389   GAL1_CLOAB Galactokinase OS=5710 / VKM B-1787...420.035     40     43     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
22Q9K3S8    387   GAL1_STRCO Galactokinase OS=Streptomyces coel...2710.047     39.7     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
23B1LCQ5    350   GAL1_THESQ Galactokinase OS=Thermotoga sp. (s...1860.19     37.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
24A5IMZ6    350   GAL1_THEP1 Galactokinase OS=Thermotoga petrop...1860.19     37.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
25P39574    390   GAL1_BACSU Galactokinase OS=Bacillus subtilis...2790.25     37.4     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
26Q8R8R7    390   GAL1_THETN Galactokinase OS=100824 / MB4) (Ca...2720.32     37     22     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
27Q3AAV5    304   KHSE_CARHZ Homoserine kinase OS=Carboxydother...570.36     36.6     39     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004413; F:homoserine kinase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
28B7IDE2    352   GAL1_THEAB Galactokinase OS=Thermosipho afric...630.46     36.2     35     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
29Q117D0    305   KHSE_TRIEI Homoserine kinase OS=Trichodesmium...1790.82     35.4     28     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004413; F:homoserine kinase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
30Q9R0N0    391   GALK1_MOUSE Galactokinase OS=Mus musculus (Mo...2730.93     35.4     23     43GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004335; F:galactokinase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
31Q8R711    312   KHSE_THETN Homoserine kinase OS=100824 / MB4)...600.97     35     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004413; F:homoserine kinase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
records
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