rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P35187 | 1447 | SGS1_YEAST ATP-dependent helicase SGS1 OS=Sac... | 1447 | 0 | 3016 | 100 | 100 | GO:0005730; C:nucleolus; IDA:SGD.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:SGD.::GO:0031292; P:gene conversion at mating-type locus, DNA double-strand break processing; IGI:SGD.::GO:0031573; P:intra-S DNA damage checkpoint; IMP:SGD.::GO:0045132; P:meiotic chromosome segregation; IMP:SGD.::GO:0000070; P:mitotic sister chromatid segregation; IMP:SGD.::GO:0010947; P:negative regulation of meiotic joint molecule formation; IGI:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0000722; P:telomere maintenance via recombination; IMP:SGD.::GO:0031860; P:telomeric 3' overhang formation; IGI:SGD. | 2 | Q09811 | 1328 | HUS2_SCHPO ATP-dependent DNA helicase hus2/rq... | 674 | 1e-164 | 537 | 43 | 61 | GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:PomBase.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:PomBase.::GO:0003677; F:DNA binding; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0006268; P:DNA unwinding involved in replication; ISS:PomBase.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:PomBase.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0045950; P:negative regulation of mitotic recombination; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0034065; P:replication fork processing at rDNA locus; IGI:PomBase.::GO:0071140; P:resolution of mitotic recombination intermediates; IMP:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.::GO:0009650; P:UV protection; IMP:PomBase. | 3 | Q9VGI8 | 1487 | BLM_DROME Bloom syndrome protein homolog OS=D... | 573 | 6e-137 | 464 | 41 | 62 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:FlyBase.::GO:0000739; F:DNA strand annealing activity; IDA:FlyBase.::GO:0000403; F:Y-form DNA binding; IDA:FlyBase. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:FlyBase.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.::GO:0000732; P:strand displacement; IDA:FlyBase. | 4 | Q8L840 | 1188 | RQL4A_ARATH ATP-dependent DNA helicase Q-like... | 594 | 1e-136 | 457 | 41 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0071215; P:cellular response to abscisic acid stimulus; IEP:UniProtKB.::GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0051276; P:chromosome organization; IMP:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:TAIR. | 5 | Q9FT70 | 1150 | RQL4B_ARATH ATP-dependent DNA helicase Q-like... | 628 | 5e-133 | 447 | 40 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0006310; P:DNA recombination; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro. | 6 | P46063 | 649 | RECQ1_HUMAN ATP-dependent DNA helicase Q1 OS=... | 560 | 1e-130 | 425 | 41 | 61 | GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006260; P:DNA replication; IEA:InterPro. | 7 | Q9DEY9 | 1364 | BLM_XENLA Bloom syndrome protein homolog OS=X... | 570 | 1e-129 | 442 | 41 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 8 | Q5RF63 | 649 | RECQ1_PONAB ATP-dependent DNA helicase Q1 OS=... | 560 | 5e-129 | 421 | 40 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro. | 9 | Q6AYJ1 | 621 | RECQ1_RAT ATP-dependent DNA helicase Q1 OS=Ra... | 555 | 1e-128 | 419 | 40 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro. | 10 | P54132 | 1417 | BLM_HUMAN Bloom syndrome protein OS=Homo sapi... | 555 | 6e-127 | 435 | 40 | 61 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0000800; C:lateral element; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; NAS:UniProtKB.::GO:0000085; P:G2 phase of mitotic cell cycle; NAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; NAS:UniProtKB.::GO:0051782; P:negative regulation of cell division; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:UniProtKB.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0048478; P:replication fork protection; NAS:UniProtKB.::GO:0010165; P:response to X-ray; IDA:UniProtKB. | 11 | Q9Z129 | 648 | RECQ1_MOUSE ATP-dependent DNA helicase Q1 OS=... | 566 | 7e-126 | 412 | 39 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro. | 12 | O88700 | 1416 | BLM_MOUSE Bloom syndrome protein homolog OS=M... | 551 | 3e-125 | 430 | 40 | 60 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001673; C:male germ cell nucleus; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0005657; C:replication fork; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0046632; P:alpha-beta T cell differentiation; IMP:MGI.::GO:0051276; P:chromosome organization; IMP:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0045950; P:negative regulation of mitotic recombination; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0051098; P:regulation of binding; IDA:MGI. | 13 | Q9I920 | 1142 | BLM_CHICK Bloom syndrome protein homolog OS=G... | 571 | 1e-124 | 423 | 40 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro. | 14 | Q9FT73 | 705 | RQL2_ARATH ATP-dependent DNA helicase Q-like ... | 544 | 3e-114 | 382 | 38 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0006310; P:DNA recombination; IC:TAIR.::GO:0006281; P:DNA repair; IC:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro. | 15 | O18017 | 988 | BLM_CAEEL Bloom syndrome protein homolog OS=C... | 541 | 5e-111 | 381 | 38 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:WormBase. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:WormBase.::GO:0051276; P:chromosome organization; IGI:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0051307; P:meiotic chromosome separation; IMP:WormBase.::GO:0007067; P:mitosis; IGI:WormBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:WormBase.::GO:0010165; P:response to X-ray; IMP:WormBase. | 16 | Q9FT74 | 606 | RQL1_ARATH ATP-dependent DNA helicase Q-like ... | 407 | 2e-110 | 368 | 45 | 64 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0042631; P:cellular response to water deprivation; IEP:UniProtKB.::GO:0006310; P:DNA recombination; IEA:InterPro. | 17 | Q9TXJ8 | 631 | RECQ1_CAEEL Putative ATP-dependent DNA helica... | 617 | 3e-106 | 357 | 34 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro. | 18 | A8WK63 | 618 | RECQ1_CAEBR Putative ATP-dependent DNA helica... | 445 | 5e-103 | 347 | 39 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro. | 19 | Q9CL21 | 632 | RECQ_PASMU ATP-dependent DNA helicase recQ OS... | 549 | 9e-100 | 338 | 36 | 57 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:InterPro. | 20 | P15043 | 609 | RECQ_ECOLI ATP-dependent DNA helicase recQ OS... | 544 | 7e-98 | 332 | 35 | 56 | GO:0043590; C:bacterial nucleoid; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:EcoliWiki.::GO:0030894; C:replisome; IDA:UniProtKB.::GO:0017117; C:single-stranded DNA-dependent ATP-dependent DNA helicase complex; IDA:EcoliWiki. | | | | | | | | | | GO:0005524; F:ATP binding; IPI:EcoliWiki.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IDA:EcoliWiki.::GO:0005515; F:protein binding; IPI:EcoliWiki.::GO:0017116; F:single-stranded DNA-dependent ATP-dependent DNA helicase activity; IDA:EcoliWiki.::GO:0008270; F:zinc ion binding; IMP:EcoliWiki. | | | | | | | | | | GO:0006310; P:DNA recombination; IDA:EcoliWiki.::GO:0006281; P:DNA repair; IGI:EcoliWiki.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 21 | Q9FT72 | 713 | RQL3_ARATH ATP-dependent DNA helicase Q-like ... | 416 | 3e-97 | 334 | 41 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043138; F:3'-5' DNA helicase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IDA:TAIR.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IDA:UniProtKB. | 22 | P40724 | 609 | RECQ_SALTY ATP-dependent DNA helicase recQ OS... | 552 | 5e-97 | 330 | 36 | 55 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 23 | P71359 | 619 | RECQ_HAEIN ATP-dependent DNA helicase recQ OS... | 489 | 1e-93 | 320 | 38 | 58 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:InterPro. | 24 | Q5UPX0 | 548 | YR290_MIMIV Putative ATP-dependent RNA helica... | 509 | 3e-87 | 300 | 36 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro. | 25 | O94762 | 991 | RECQ5_HUMAN ATP-dependent DNA helicase Q5 OS=... | 449 | 1e-86 | 309 | 38 | 57 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003678; F:DNA helicase activity; NAS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc. | 26 | O34748 | 591 | RECQ_BACSU Probable ATP-dependent DNA helicas... | 521 | 8e-84 | 291 | 34 | 55 | GO:0043590; C:bacterial nucleoid; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 27 | Q19546 | 1056 | WRN_CAEEL Probable Werner syndrome ATP-depend... | 593 | 1e-82 | 299 | 34 | 50 | GO:0005694; C:chromosome; IDA:WormBase.::GO:0005654; C:nucleoplasm; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:WormBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase. | 28 | O93530 | 1436 | WRN_XENLA Werner syndrome ATP-dependent helic... | 424 | 2e-76 | 283 | 40 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro. | 29 | O09053 | 1401 | WRN_MOUSE Werner syndrome ATP-dependent helic... | 689 | 2e-75 | 280 | 32 | 48 | GO:0005654; C:nucleoplasm; IDA:MGI. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0010259; P:multicellular organismal aging; IGI:MGI.::GO:0040009; P:regulation of growth rate; IMP:MGI.::GO:0001302; P:replicative cell aging; IMP:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI. | 30 | Q14191 | 1432 | WRN_HUMAN Werner syndrome ATP-dependent helic... | 678 | 2e-72 | 271 | 32 | 48 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:MGI. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IDA:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.::GO:0010259; P:multicellular organismal aging; IMP:UniProtKB.::GO:0032066; P:nucleolus to nucleoplasm transport; IDA:MGI.::GO:0051345; P:positive regulation of hydrolase activity; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IGI:MGI.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0010225; P:response to UV-C; IDA:UniProtKB.::GO:0000723; P:telomere maintenance; IMP:UniProtKB. | 31 | P50729 | 496 | RECS_BACSU Probable ATP-dependent DNA helicas... | 353 | 5e-64 | 232 | 36 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro. |