Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR190C
Length:
1447
Number of sequences:
5887
Description:
YMR190C SGS1 SGDID:S000004802, Chr XIII from 645258-640915, Genome Release 64-1-1, reverse complement, Verified ORF, "Nucleolar DNA helicase of the RecQ family; involved in genome integrity maintenance; regulates chromosome synapsis and meiotic joint molecule/crossover formation; potential role as repressor of a subset of rapamycin responsive genes; rapidly lost in response to rapamycin in Rrd1p-dependent manner; similar to human BLM and WRN proteins implicated in Bloom and Werner syndromes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P35187    1447   SGS1_YEAST ATP-dependent helicase SGS1 OS=Sac...14470     3016     100     100GO:0005730; C:nucleolus; IDA:SGD.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:SGD.::GO:0031292; P:gene conversion at mating-type locus, DNA double-strand break processing; IGI:SGD.::GO:0031573; P:intra-S DNA damage checkpoint; IMP:SGD.::GO:0045132; P:meiotic chromosome segregation; IMP:SGD.::GO:0000070; P:mitotic sister chromatid segregation; IMP:SGD.::GO:0010947; P:negative regulation of meiotic joint molecule formation; IGI:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0000722; P:telomere maintenance via recombination; IMP:SGD.::GO:0031860; P:telomeric 3' overhang formation; IGI:SGD.
2Q09811    1328   HUS2_SCHPO ATP-dependent DNA helicase hus2/rq...6741e-164     537     43     61GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:PomBase.::GO:0003677; F:DNA binding; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0006268; P:DNA unwinding involved in replication; ISS:PomBase.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:PomBase.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0045950; P:negative regulation of mitotic recombination; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0034065; P:replication fork processing at rDNA locus; IGI:PomBase.::GO:0071140; P:resolution of mitotic recombination intermediates; IMP:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.::GO:0009650; P:UV protection; IMP:PomBase.
3Q9VGI8    1487   BLM_DROME Bloom syndrome protein homolog OS=D...5736e-137     464     41     62GO:0005634; C:nucleus; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:FlyBase.::GO:0000739; F:DNA strand annealing activity; IDA:FlyBase.::GO:0000403; F:Y-form DNA binding; IDA:FlyBase.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:FlyBase.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.::GO:0000732; P:strand displacement; IDA:FlyBase.
4Q8L840    1188   RQL4A_ARATH ATP-dependent DNA helicase Q-like...5941e-136     457     41     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0071215; P:cellular response to abscisic acid stimulus; IEP:UniProtKB.::GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0051276; P:chromosome organization; IMP:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:TAIR.
5Q9FT70    1150   RQL4B_ARATH ATP-dependent DNA helicase Q-like...6285e-133     447     40     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0006310; P:DNA recombination; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
6P46063    649   RECQ1_HUMAN ATP-dependent DNA helicase Q1 OS=...5601e-130     425     41     61GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006260; P:DNA replication; IEA:InterPro.
7Q9DEY9    1364   BLM_XENLA Bloom syndrome protein homolog OS=X...5701e-129     442     41     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
8Q5RF63    649   RECQ1_PONAB ATP-dependent DNA helicase Q1 OS=...5605e-129     421     40     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
9Q6AYJ1    621   RECQ1_RAT ATP-dependent DNA helicase Q1 OS=Ra...5551e-128     419     40     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
10P54132    1417   BLM_HUMAN Bloom syndrome protein OS=Homo sapi...5556e-127     435     40     61GO:0005737; C:cytoplasm; IDA:HPA.::GO:0000800; C:lateral element; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.
GO:0000724; P:double-strand break repair via homologous recombination; NAS:UniProtKB.::GO:0000085; P:G2 phase of mitotic cell cycle; NAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; NAS:UniProtKB.::GO:0051782; P:negative regulation of cell division; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:UniProtKB.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0048478; P:replication fork protection; NAS:UniProtKB.::GO:0010165; P:response to X-ray; IDA:UniProtKB.
11Q9Z129    648   RECQ1_MOUSE ATP-dependent DNA helicase Q1 OS=...5667e-126     412     39     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
12O88700    1416   BLM_MOUSE Bloom syndrome protein homolog OS=M...5513e-125     430     40     60GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001673; C:male germ cell nucleus; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0005657; C:replication fork; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0046632; P:alpha-beta T cell differentiation; IMP:MGI.::GO:0051276; P:chromosome organization; IMP:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0045950; P:negative regulation of mitotic recombination; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0051098; P:regulation of binding; IDA:MGI.
13Q9I920    1142   BLM_CHICK Bloom syndrome protein homolog OS=G...5711e-124     423     40     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
14Q9FT73    705   RQL2_ARATH ATP-dependent DNA helicase Q-like ...5443e-114     382     38     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006310; P:DNA recombination; IC:TAIR.::GO:0006281; P:DNA repair; IC:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.
15O18017    988   BLM_CAEEL Bloom syndrome protein homolog OS=C...5415e-111     381     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:WormBase.
GO:0006916; P:anti-apoptosis; IMP:WormBase.::GO:0051276; P:chromosome organization; IGI:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0051307; P:meiotic chromosome separation; IMP:WormBase.::GO:0007067; P:mitosis; IGI:WormBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:WormBase.::GO:0010165; P:response to X-ray; IMP:WormBase.
16Q9FT74    606   RQL1_ARATH ATP-dependent DNA helicase Q-like ...4072e-110     368     45     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0042631; P:cellular response to water deprivation; IEP:UniProtKB.::GO:0006310; P:DNA recombination; IEA:InterPro.
17Q9TXJ8    631   RECQ1_CAEEL Putative ATP-dependent DNA helica...6173e-106     357     34     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:InterPro.
18A8WK63    618   RECQ1_CAEBR Putative ATP-dependent DNA helica...4455e-103     347     39     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:InterPro.
19Q9CL21    632   RECQ_PASMU ATP-dependent DNA helicase recQ OS...5499e-100     338     36     57GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:InterPro.
20P15043    609   RECQ_ECOLI ATP-dependent DNA helicase recQ OS...5447e-98     332     35     56GO:0043590; C:bacterial nucleoid; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:EcoliWiki.::GO:0030894; C:replisome; IDA:UniProtKB.::GO:0017117; C:single-stranded DNA-dependent ATP-dependent DNA helicase complex; IDA:EcoliWiki.
GO:0005524; F:ATP binding; IPI:EcoliWiki.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IDA:EcoliWiki.::GO:0005515; F:protein binding; IPI:EcoliWiki.::GO:0017116; F:single-stranded DNA-dependent ATP-dependent DNA helicase activity; IDA:EcoliWiki.::GO:0008270; F:zinc ion binding; IMP:EcoliWiki.
GO:0006310; P:DNA recombination; IDA:EcoliWiki.::GO:0006281; P:DNA repair; IGI:EcoliWiki.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
21Q9FT72    713   RQL3_ARATH ATP-dependent DNA helicase Q-like ...4163e-97     334     41     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043138; F:3'-5' DNA helicase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IDA:TAIR.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IDA:UniProtKB.
22P40724    609   RECQ_SALTY ATP-dependent DNA helicase recQ OS...5525e-97     330     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
23P71359    619   RECQ_HAEIN ATP-dependent DNA helicase recQ OS...4891e-93     320     38     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:InterPro.
24Q5UPX0    548   YR290_MIMIV Putative ATP-dependent RNA helica...5093e-87     300     36     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
25O94762    991   RECQ5_HUMAN ATP-dependent DNA helicase Q5 OS=...4491e-86     309     38     57GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003678; F:DNA helicase activity; NAS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc.
26O34748    591   RECQ_BACSU Probable ATP-dependent DNA helicas...5218e-84     291     34     55GO:0043590; C:bacterial nucleoid; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
27Q19546    1056   WRN_CAEEL Probable Werner syndrome ATP-depend...5931e-82     299     34     50GO:0005694; C:chromosome; IDA:WormBase.::GO:0005654; C:nucleoplasm; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:WormBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase.
28O93530    1436   WRN_XENLA Werner syndrome ATP-dependent helic...4242e-76     283     40     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro.
29O09053    1401   WRN_MOUSE Werner syndrome ATP-dependent helic...6892e-75     280     32     48GO:0005654; C:nucleoplasm; IDA:MGI.
GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0010259; P:multicellular organismal aging; IGI:MGI.::GO:0040009; P:regulation of growth rate; IMP:MGI.::GO:0001302; P:replicative cell aging; IMP:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI.
30Q14191    1432   WRN_HUMAN Werner syndrome ATP-dependent helic...6782e-72     271     32     48GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:MGI.
GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.
GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IDA:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.::GO:0010259; P:multicellular organismal aging; IMP:UniProtKB.::GO:0032066; P:nucleolus to nucleoplasm transport; IDA:MGI.::GO:0051345; P:positive regulation of hydrolase activity; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IGI:MGI.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0010225; P:response to UV-C; IDA:UniProtKB.::GO:0000723; P:telomere maintenance; IMP:UniProtKB.
31P50729    496   RECS_BACSU Probable ATP-dependent DNA helicas...3535e-64     232     36     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.
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