rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q03214 | 1411 | ECM5_YEAST Protein ECM5 OS=Saccharomyces cere... | 1411 | 0 | 2910 | 100 | 100 | GO:0070211; C:Snt2C complex; IDA:SGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031505; P:fungal-type cell wall organization; IMP:SGD. | 2 | Q9US53 | 715 | JMJ2_SCHPO Jumonji/ARID domain-containing pro... | 54 | 0.12 | 40.4 | 30 | 50 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:PomBase.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:PomBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:PomBase. | | | | | | | | | | GO:0006338; P:chromatin remodeling; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:PomBase. | 3 | Q9VMJ7 | 1838 | KDM5_DROME Lysine-specific demethylase lid OS... | 168 | 0.00000000005 | 71.6 | 27 | 49 | GO:0070822; C:Sin3-type complex; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0043992; F:histone acetyltransferase activity (H3-K9 specific); IMP:FlyBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IMP:FlyBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q62240 | 1548 | KDM5D_MOUSE Lysine-specific demethylase 5D OS... | 36 | 2.8 | 36.2 | 31 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 5 | P41229 | 1560 | KDM5C_HUMAN Lysine-specific demethylase 5C OS... | 60 | 0.18 | 40 | 27 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q38JA7 | 1556 | KDM5C_CANFA Lysine-specific demethylase 5C OS... | 33 | 0.77 | 38.1 | 33 | 64 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q6IQX0 | 1503 | KD5BB_DANRE Lysine-specific demethylase 5B-B ... | 91 | 0.74 | 38.1 | 31 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q30DN6 | 1545 | KDM5D_CANFA Lysine-specific demethylase 5D OS... | 28 | 0.58 | 38.5 | 36 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 9 | P29375 | 1690 | KDM5A_HUMAN Lysine-specific demethylase 5A OS... | 31 | 0.076 | 41.2 | 42 | 71 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 10 | Q3UXZ9 | 1690 | KDM5A_MOUSE Lysine-specific demethylase 5A OS... | 31 | 0.073 | 41.6 | 42 | 71 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | P41230 | 1554 | KDM5C_MOUSE Lysine-specific demethylase 5C OS... | 28 | 1.4 | 37.4 | 32 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q9BY66 | 1539 | KDM5D_HUMAN Lysine-specific demethylase 5D OS... | 63 | 0.033 | 42.7 | 25 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007283; P:spermatogenesis; NAS:UniProtKB. | 13 | Q5F363 | 1233 | JARD2_CHICK Protein Jumonji OS=Gallus gallus ... | 584 | 0.000000000001 | 76.6 | 22 | 36 | GO:0035097; C:histone methyltransferase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q5F3R2 | 1522 | KDM5B_CHICK Lysine-specific demethylase 5B OS... | 80 | 7 | 35 | 29 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q5XUN4 | 1535 | KDM5D_PANTR Lysine-specific demethylase 5D OS... | 184 | 0.045 | 42 | 19 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 16 | Q6BDA0 | 1340 | ELF6_ARATH Probable lysine-specific demethyla... | 228 | 0.000000000002 | 76.3 | 25 | 38 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033169; P:histone H3-K9 demethylation; IMP:TAIR.::GO:0048579; P:negative regulation of long-day photoperiodism, flowering; IMP:TAIR.::GO:0048577; P:negative regulation of short-day photoperiodism, flowering; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0009741; P:response to brassinosteroid stimulus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009826; P:unidimensional cell growth; IMP:TAIR. | 17 | Q80Y84 | 1544 | KDM5B_MOUSE Lysine-specific demethylase 5B OS... | 62 | 0.026 | 42.7 | 24 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q9UGL1 | 1544 | KDM5B_HUMAN Lysine-specific demethylase 5B OS... | 62 | 0.024 | 43.1 | 24 | 47 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:GDB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q92833 | 1246 | JARD2_HUMAN Protein Jumonji OS=Homo sapiens (... | 182 | 2.7 | 36.2 | 26 | 40 | | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q23541 | 1477 | KDM5_CAEEL Lysine-specific demethylase rbr-2 ... | 141 | 0.00008 | 51.2 | 28 | 43 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:WormBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:WormBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q9UT79 | 1588 | MSC1_SCHPO Multicopy suppressor of chk1 prote... | 206 | 0.0006 | 48.1 | 21 | 37 | GO:0000118; C:histone deacetylase complex; IDA:PomBase.::GO:0000812; C:Swr1 complex; IDA:PomBase. | | | | | | | | | | GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016573; P:histone acetylation; IMP:PomBase.::GO:0007126; P:meiosis; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase. | 22 | Q9STM3 | 1360 | REF6_ARATH Lysine-specific demethylase REF6 O... | 328 | 0.000000007 | 64.7 | 21 | 35 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033169; P:histone H3-K9 demethylation; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0035067; P:negative regulation of histone acetylation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009741; P:response to brassinosteroid stimulus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR. | 23 | Q61T02 | 1482 | KDM5_CAEBR Lysine-specific demethylase rbr-2 ... | 134 | 0.00008 | 51.2 | 28 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q9HDV4 | 1513 | LID2_SCHPO Lid2 complex component lid2 OS=Sch... | 127 | 1.4 | 37.4 | 24 | 42 | GO:0048189; C:Lid2 complex; IDA:PomBase.::GO:0031934; C:mating-type region heterochromatin; IDA:PomBase.::GO:0031618; C:nuclear centromeric heterochromatin; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:PomBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0031507; P:heterochromatin assembly; IMP:PomBase.::GO:0051567; P:histone H3-K9 methylation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0034630; P:RITS complex localization; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | A1YVX4 | 1516 | KDM5C_PIG Lysine-specific demethylase 5C OS=S... | 52 | 0.11 | 40.8 | 35 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | O02326 | 467 | CFI1_CAEEL AT-rich interactive domain-contain... | 107 | 0.000004 | 54.7 | 36 | 55 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045165; P:cell fate commitment; IMP:WormBase.::GO:0030182; P:neuron differentiation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q8IN94 | 2716 | OSA_DROME Trithorax group protein osa OS=Dros... | 75 | 0.000007 | 54.7 | 41 | 56 | GO:0035060; C:brahma complex; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:UniProtKB.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0046530; P:photoreceptor cell differentiation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007379; P:segment specification; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IGI:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IMP:UniProtKB. | 28 | Q24573 | 911 | DRI_DROME Protein dead ringer OS=Drosophila m... | 105 | 0.00002 | 53.1 | 34 | 52 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:FlyBase.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:FlyBase. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0009880; P:embryonic pattern specification; IMP:FlyBase.::GO:0042063; P:gliogenesis; IMP:UniProtKB.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045924; P:regulation of female receptivity; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; NAS:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q1LVC2 | 1319 | JARD2_DANRE Protein Jumonji OS=Danio rerio (Z... | 76 | 0.00005 | 52 | 36 | 55 | GO:0035097; C:histone methyltransferase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q62315 | 1234 | JARD2_MOUSE Protein Jumonji OS=Mus musculus (... | 182 | 1.6 | 37 | 26 | 40 | | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0001889; P:liver development; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0031061; P:negative regulation of histone methylation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0051574; P:positive regulation of histone H3-K9 methylation; IDA:UniProtKB.::GO:0048536; P:spleen development; IMP:MGI.::GO:0048863; P:stem cell differentiation; IMP:UniProtKB.::GO:0048538; P:thymus development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | Q4H3P5 | 571 | DRI_CIOIN Protein dead ringer homolog OS=Cion... | 94 | 0.00005 | 51.6 | 35 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |