Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR167W
Length:
769
Number of sequences:
5887
Description:
YMR167W MLH1 SGDID:S000004777, Chr XIII from 594886-597195, Genome Release 64-1-1, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451P73349    556   MUTL_SYNY3 DNA mismatch repair protein mutL O...3431e-31     134     28     49
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
452Q256F3    580   MUTL_CHLFF DNA mismatch repair protein mutL O...3414e-31     132     26     49
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
453B7JY11    561   MUTL_CYAP8 DNA mismatch repair protein mutL O...3381e-29     127     28     50
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
454P54277    932   PMS1_HUMAN PMS1 protein homolog 1 OS=Homo sap...3592e-29     129     27     47GO:0032389; C:MutLalpha complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
455Q72J22    545   MUTL_THET2 DNA mismatch repair protein mutL O...3132e-27     121     28     49
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
456Q9RA54    545   MUTL_THET8 DNA mismatch repair protein mutL O...2978e-27     119     29     49
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
457B1X109    554   MUTL_CYAA5 DNA mismatch repair protein mutL O...3461e-26     119     29     48
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
458B2IYW1    568   MUTL_NOSP7 DNA mismatch repair protein mutL O...4155e-26     117     25     44
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
459P96082    533   MUTL_THEAQ DNA mismatch repair protein mutL O...3123e-24     110     27     47
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
460Q3MEV6    563   MUTL_ANAVT DNA mismatch repair protein mutL O...3645e-23     107     24     46
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
461Q12083    715   MLH3_YEAST DNA mismatch repair protein MLH3 O...1771e-22     107     33     58GO:0005712; C:chiasma; IBA:RefGenome.::GO:0032390; C:MutLbeta complex; IPI:SGD.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006298; P:mismatch repair; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.
462A4D2B8    440   PM2P1_HUMAN Putative postmeiotic segregation ...1541e-22     105     36     64GO:0032389; C:MutLalpha complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
463Q8YSM9    563   MUTL_NOSS1 DNA mismatch repair protein mutL O...3721e-22     106     23     45
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
464O95744    297   PM2P2_HUMAN Putative postmeiotic segregation ...1595e-20     95.5     33     64GO:0032389; C:MutLalpha complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
465Q07980    695   MLH2_YEAST DNA mismatch repair protein MLH2 O...3452e-18     93.6     27     47GO:0032389; C:MutLalpha complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006298; P:mismatch repair; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.
466Q9UHC1    1453   MLH3_HUMAN DNA mismatch repair protein Mlh3 O...1890.00000000000003     80.9     31     50GO:0005712; C:chiasma; IBA:RefGenome.::GO:0032390; C:MutLbeta complex; IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003696; F:satellite DNA binding; TAS:ProtInc.
GO:0006298; P:mismatch repair; NAS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; NAS:UniProtKB.
467Q13401    168   PM2P3_HUMAN Putative postmeiotic segregation ...660.000000008     59.7     38     73GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
468Q13670    270   PM2PB_HUMAN Putative postmeiotic segregation ...610.0000002     56.6     39     74GO:0032389; C:MutLalpha complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
469P25391    3075   LAMA1_HUMAN Laminin subunit alpha-1 OS=Homo s...1340.04     41.2     29     44GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005606; C:laminin-1 complex; IDA:UniProtKB.::GO:0005608; C:laminin-3 complex; IPI:UniProtKB.
GO:0005201; F:extracellular matrix structural constituent; ISS:UniProtKB.::GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
470P19967    436   CYB5R_DROME Cytochrome b5-related protein OS=...1530.67     37     26     39GO:0005739; C:mitochondrion; IDA:FlyBase.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
471A5GF83    159   RIMP_GEOUR Ribosome maturation factor RimP OS...423.1     33.5     36     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
472Q6GJ10    346   GRAS_STAAR Sensor histidine kinase graS OS=St...759.5     33.1     35     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
records
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