Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR167W
Length:
769
Number of sequences:
5887
Description:
YMR167W MLH1 SGDID:S000004777, Chr XIII from 594886-597195, Genome Release 64-1-1, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38920    769   MLH1_YEAST DNA mismatch repair protein MLH1 O...7690     1566     100     100GO:0005712; C:chiasma; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0032389; C:MutLalpha complex; IPI:SGD.::GO:0032390; C:MutLbeta complex; IPI:SGD.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IMP:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000713; P:meiotic heteroduplex formation; IMP:SGD.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.
2Q9JK91    760   MLH1_MOUSE DNA mismatch repair protein Mlh1 O...7971e-163     499     37     57GO:0005712; C:chiasma; IDA:MGI.::GO:0001673; C:male germ cell nucleus; IDA:MGI.::GO:0032389; C:MutLalpha complex; IDA:MGI.::GO:0032390; C:MutLbeta complex; IBA:RefGenome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000795; C:synaptonemal complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IGI:MGI.
GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:MGI.::GO:0045190; P:isotype switching; IMP:MGI.::GO:0007060; P:male meiosis chromosome segregation; IMP:MGI.::GO:0043060; P:meiotic metaphase I plate congression; IMP:MGI.::GO:0006298; P:mismatch repair; IDA:MGI.::GO:0045950; P:negative regulation of mitotic recombination; IMP:MGI.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IMP:MGI.::GO:0048477; P:oogenesis; IMP:MGI.::GO:0000239; P:pachytene; IMP:MGI.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:MGI.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0051257; P:spindle midzone assembly involved in meiosis; IMP:MGI.
3P40692    756   MLH1_HUMAN DNA mismatch repair protein Mlh1 O...7881e-163     499     37     58GO:0005712; C:chiasma; IBA:RefGenome.::GO:0032389; C:MutLalpha complex; IBA:RefGenome.::GO:0032390; C:MutLbeta complex; IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
4P97679    757   MLH1_RAT DNA mismatch repair protein Mlh1 OS=...7894e-158     484     37     56GO:0005712; C:chiasma; IBA:RefGenome.::GO:0032389; C:MutLalpha complex; IBA:RefGenome.::GO:0032390; C:MutLbeta complex; IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IEP:RGD.
5Q9P7W6    684   MLH1_SCHPO Putative MutL protein homolog 1 OS...7789e-140     434     38     56GO:0005712; C:chiasma; ISS:RefGenome.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0032389; C:MutLalpha complex; ISS:RefGenome.::GO:0032390; C:MutLbeta complex; ISS:RefGenome.::GO:0005816; C:spindle pole body; IDA:PomBase.::GO:0000795; C:synaptonemal complex; ISS:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; ISS:RefGenome.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; TAS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; ISS:RefGenome.
6Q54KD8    884   MLH1_DICDI DNA mismatch repair protein Mlh1 O...8481e-118     385     33     50GO:0005712; C:chiasma; IBA:RefGenome.::GO:0032389; C:MutLalpha complex; IBA:RefGenome.::GO:0032390; C:MutLbeta complex; IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0016887; F:ATPase activity; ISS:dictyBase.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
GO:0006298; P:mismatch repair; ISS:dictyBase.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
7B3PDC3    626   MUTL_CELJU DNA mismatch repair protein mutL O...3602e-64     231     37     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
8Q8F6X4    593   MUTL_LEPIN DNA mismatch repair protein mutL O...3172e-59     217     38     58GO:0032300; C:mismatch repair complex; ISS:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; ISS:RefGenome.::GO:0030983; F:mismatched DNA binding; ISS:RefGenome.
GO:0006298; P:mismatch repair; ISS:RefGenome.
9Q72PF7    593   MUTL_LEPIC DNA mismatch repair protein mutL O...3172e-59     217     38     58
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
10A6VD59    633   MUTL_PSEA7 DNA mismatch repair protein mutL O...3543e-58     214     34     54GO:0032300; C:mismatch repair complex; ISS:RefGenome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; ISS:RefGenome.::GO:0030983; F:mismatched DNA binding; ISS:RefGenome.
GO:0006298; P:mismatch repair; ISS:RefGenome.
11Q04Z69    596   MUTL_LEPBL DNA mismatch repair protein mutL O...3175e-58     213     38     57
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
12Q9HUL8    633   MUTL_PSEAE DNA mismatch repair protein mutL O...3546e-58     213     34     54
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
13B7V209    633   MUTL_PSEA8 DNA mismatch repair protein mutL O...3546e-58     213     34     54
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
14Q04QW2    596   MUTL_LEPBJ DNA mismatch repair protein mutL O...3176e-58     213     38     57
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
15Q02F72    633   MUTL_PSEAB DNA mismatch repair protein mutL O...3546e-58     213     34     54
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
16C1DLQ0    641   MUTL_AZOVD DNA mismatch repair protein mutL O...3367e-58     213     37     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
17Q87VJ2    645   MUTL_PSESM DNA mismatch repair protein mutL O...3581e-57     213     34     53
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
18A8Z1W7    669   MUTL_STAAT DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
19Q6GHD9    669   MUTL_STAAR DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
20A6QGJ5    669   MUTL_STAAE DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
21Q5HGD5    669   MUTL_STAAC DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
22Q93T05    669   MUTL_STAA8 DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
23Q2FHE2    669   MUTL_STAA3 DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
24Q8NWX9    669   MUTL_STAAW DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
25Q6G9R7    669   MUTL_STAAS DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
26P65492    669   MUTL_STAAN DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
27P65491    669   MUTL_STAAM DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
28A6U1B5    669   MUTL_STAA2 DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
29A7X1T8    669   MUTL_STAA1 DNA mismatch repair protein mutL O...3333e-57     211     39     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
30B0KKZ7    632   MUTL_PSEPG DNA mismatch repair protein mutL O...3335e-57     211     35     55
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
31Q9JTS2    658   MUTL_NEIMA DNA mismatch repair protein mutL O...3328e-57     210     36     56
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
records
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