UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR146C

Length:

347

Number of sequences:

5887

Description:

YMR146C TIF34 SGDID:S000004754, Chr XIII from 558524-557481, Genome Release 64-1-1, reverse complement, Verified ORF, "eIF3i subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation; stimulates rate of ribosomal scanning during translation reinitiation"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
601	Q6H8D5	910	COB22_ORYSJ Coatomer subunit beta'-2 OS=Oryza...	79	0.67	35.8	32	48	GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
									GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
602	Q0III3	612	DC1I2_BOVIN Cytoplasmic dynein 1 intermediate...	192	0.002	43.9	24	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0031982; C:vesicle; ISS:UniProtKB.
									GO:0003774; F:motor activity; IEA:UniProtKB-KW.
									GO:0006810; P:transport; IEA:UniProtKB-KW.
603	Q20059	683	WDR48_CAEEL WD repeat-containing protein 48 h...	47	0.58	35.8	30	60
604	A8ID74	797	BOP1_CHLRE Ribosome biogenesis protein BOP1 h...	56	0.002	43.5	36	59	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
605	B4MY77	335	CIAO1_DROWI Probable cytosolic iron-sulfur pr...	123	0.016	40.4	28	46
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
606	Q8TEQ6	1508	GEMI5_HUMAN Gem-associated protein 5 OS=Homo ...	83	0.026	40.4	34	48	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0017069; F:snRNA binding; IDA:UniProtKB.
									GO:0034660; P:ncRNA metabolic process; TAS:Reactome.::GO:0006461; P:protein complex assembly; TAS:UniProtKB.::GO:0000387; P:spliceosomal snRNP assembly; TAS:UniProtKB.
607	Q4PHV3	587	IPI3_USTMA Pre-rRNA-processing protein IPI3 O...	159	1.9	34.3	21	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
608	Q10051	492	PRP19_CAEEL Pre-mRNA-processing factor 19 hom...	180	0.095	38.1	22	39	GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
609	Q6FVD3	840	HIR1_CANGA Protein HIR1 OS=NRRL Y-65) (Yeast)...	314	0.15	37.7	22	39	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
610	Q652L2	975	HIRA_ORYSJ Protein HIRA OS=Oryza sativa subsp...	232	0.002	43.5	21	39	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
611	Q9SYX2	1029	SPA1_ARATH Protein SUPPRESSOR OF PHYA-105 1 O...	89	0.002	43.5	33	47	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.
									GO:0009658; P:chloroplast organization; IMP:TAIR.::GO:0010100; P:negative regulation of photomorphogenesis; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IGI:TAIR.::GO:2000028; P:regulation of photoperiodism, flowering; IMP:TAIR.::GO:0010218; P:response to far red light; IEP:TAIR.::GO:0010114; P:response to red light; IEP:TAIR.::GO:0048575; P:short-day photoperiodism, flowering; IMP:TAIR.
612	Q9I9H8	1261	APAF_DANRE Apoptotic protease-activating fact...	85	0.25	37	26	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006952; P:defense response; IEA:InterPro.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
613	P87177	922	YB1C_SCHPO Uncharacterized WD repeat-containi...	59	7	32.3	31	46	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0032040; C:small-subunit processome; ISS:PomBase.
									GO:0030515; F:snoRNA binding; ISS:PomBase.
									GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.
614	Q63100	643	DC1I1_RAT Cytoplasmic dynein 1 intermediate c...	192	0.003	43.1	24	42	GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005868; C:cytoplasmic dynein complex; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0000922; C:spindle pole; ISS:UniProtKB.::GO:0031982; C:vesicle; ISS:UniProtKB.
									GO:0008017; F:microtubule binding; IDA:HGNC.::GO:0003777; F:microtubule motor activity; IDA:HGNC.
									GO:0047496; P:vesicle transport along microtubule; IDA:HGNC.
615	Q54ZP5	1172	WDR48_DICDI WD repeat-containing protein 48 h...	71	0.003	43.5	25	56
616	Q5ZMC3	476	WSDU1_CHICK WD repeat, SAM and U-box domain-c...	148	0.59	35.8	26	41	GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
617	A8Q2R5	660	WDR48_BRUMA WD repeat-containing protein 48 h...	75	0.52	35.8	27	45
618	Q9UMS4	504	PRP19_HUMAN Pre-mRNA-processing factor 19 OS=...	160	0.09	38.1	23	38	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:BHF-UCL.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0000245; P:spliceosomal complex assembly; IMP:BHF-UCL.
619	Q5ZMA2	505	PRP19_CHICK Pre-mRNA-processing factor 19 OS=...	160	0.036	39.7	24	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
620	Q5RKI0	606	WDR1_RAT WD repeat-containing protein 1 OS=Ra...	327	0.003	43.1	22	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
621	Q10281	314	GBLP_SCHPO Guanine nucleotide-binding protein...	288	0.42	35.8	20	35	GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005080; F:protein kinase C binding; IPI:PomBase.::GO:0043022; F:ribosome binding; IDA:PomBase.
									GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0035556; P:intracellular signal transduction; IMP:PomBase.::GO:2000766; P:negative regulation of cytoplasmic translation; ISS:PomBase.::GO:0031139; P:positive regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IGI:PomBase.::GO:0032995; P:regulation of fungal-type cell wall biogenesis; IGI:PomBase.
622	B2B766	468	LIS12_PODAN Nuclear distribution protein PAC1...	181	0.41	36.2	24	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
623	P93339	377	GBB_NICPL Guanine nucleotide-binding protein ...	228	0.11	37.7	24	39	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
624	Q4WTC4	1043	HIR1_ASPFU Protein hir1 OS=A1100) (Aspergillu...	127	0.05	39.3	24	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
625	Q759U7	461	LIS1_ASHGO Nuclear distribution protein PAC1 ...	82	0.034	39.7	27	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
626	Q17GR9	337	CIAO1_AEDAE Probable cytosolic iron-sulfur pr...	123	0.036	39.3	28	46
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
627	Q5RFQ3	918	PWP2_PONAB Periodic tryptophan protein 2 homo...	94	0.21	37.4	22	44	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
628	Q6C709	441	PRP46_YARLI Pre-mRNA-splicing factor PRP46 OS...	82	0.22	37	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
629	Q1JQD2	446	GRWD1_BOVIN Glutamate-rich WD repeat-containi...	107	0.003	42.7	30	49	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
630	Q13033	797	STRN3_HUMAN Striatin-3 OS=Homo sapiens (Human...	222	2.1	34.3	23	38	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.
									GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
									GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032355; P:response to estradiol stimulus; ISS:UniProtKB.
631	A8XSW2	691	WDR48_CAEBR WD repeat-containing protein 48 h...	104	0.13	38.1	27	46

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