Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR146C
Length:
347
Number of sequences:
5887
Description:
YMR146C TIF34 SGDID:S000004754, Chr XIII from 558524-557481, Genome Release 64-1-1, reverse complement, Verified ORF, "eIF3i subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation; stimulates rate of ribosomal scanning during translation reinitiation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481P63243    317   GBLP_BOVIN Guanine nucleotide-binding protein...2150.2     37     26     42GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
482Q09990    665   LIN23_CAEEL F-box/WD repeat-containing protei...820.03     40     30     49GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
483Q8TEB1    546   DCA11_HUMAN DDB1- and CUL4-associated factor ...2280.0002     46.6     21     40GO:0080008; C:CUL4 RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0016567; P:protein ubiquitination; IC:UniProtKB.
484A2AHJ4    1799   BRWD3_MOUSE Bromodomain and WD repeat-contain...1030.26     37     23     48
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
485O42248    317   GBLP_DANRE Guanine nucleotide-binding protein...2150.056     38.5     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
486Q7K1Y4    335   CIAO1_DROME Probable cytosolic iron-sulfur pr...1230.008     41.2     28     47
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
487Q9T014    1036   SPA2_ARATH Protein SPA1-RELATED 2 OS=Arabidop...900.0003     46.6     31     49GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
488Q2HBX6    454   LIS11_CHAGB Nuclear distribution protein PAC1...2260.002     43.9     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
489Q54JS5    1023   WDR24_DICDI WD repeat-containing protein 24 h...834.8     33.1     23     53
490P54198    1017   HIRA_HUMAN Protein HIRA OS=Homo sapiens (Huma...1230.0003     46.6     28     46GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
491Q8N9V3    476   WSDU1_HUMAN WD repeat, SAM and U-box domain-c...741.5     34.3     30     47GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
492Q61666    1015   HIRA_MOUSE Protein HIRA OS=Mus musculus (Mous...1230.0003     46.6     28     46GO:0000790; C:nuclear chromatin; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
493Q8IZU2    1322   WDR17_HUMAN WD repeat-containing protein 17 O...900.0003     46.6     32     52
494A1DHW6    689   SCONB_NEOFI Probable E3 ubiquitin ligase comp...783.5     33.5     27     46
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
495P46800    329   GBLP_DICDI Guanine nucleotide-binding protein...482.9     33.1     38     48GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
496O14727    1248   APAF_HUMAN Apoptotic protease-activating fact...3290.54     36.2     18     38GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc.
497B3MHX6    793   BOP1_DROAN Ribosome biogenesis protein BOP1 h...1350.0003     46.2     27     47GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
498Q4X0A9    696   SCONB_ASPFU Probable E3 ubiquitin ligase comp...782.1     33.9     27     47
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
499B0XTS1    696   SCONB_ASPFC Probable E3 ubiquitin ligase comp...782.1     33.9     27     47
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
500B8M7Q5    667   SCONB_TALSN Probable E3 ubiquitin ligase comp...950.001     44.3     29     48
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
501Q6RI45    1802   BRWD3_HUMAN Bromodomain and WD repeat-contain...1230.043     39.7     24     46
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
502P49026    326   GBLP_TOBAC Guanine nucleotide-binding protein...821     34.7     29     45
503Q12417    451   PRP46_YEAST Pre-mRNA-splicing factor PRP46 OS...925.5     32.7     21     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IMP:SGD.
504P59328    1117   WDHD1_MOUSE WD repeat and HMG-box DNA-binding...1780.0004     46.2     24     42GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
505Q23256    501   YH92_CAEEL Uncharacterized WD repeat-containi...2300.0004     45.8     21     40
506Q40687    380   GBB_ORYSJ Guanine nucleotide-binding protein ...3280.49     35.8     20     36
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; IEP:Gramene.
507Q00664    444   LIS1_EMENI Nuclear distribution protein nudF ...2130.22     37     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
508Q55AR8    355   SNR40_DICDI U5 small nuclear ribonucleoprotei...2280.0006     44.7     24     39GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:dictyBase.
509A0AUS0    487   WSDU1_DANRE WD repeat, SAM and U-box domain-c...2350.35     36.6     20     37GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
510A1C7E4    700   SCONB_ASPCL Probable E3 ubiquitin ligase comp...781.7     34.3     28     46
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
511Q91VU6    549   DCA11_MOUSE DDB1- and CUL4-associated factor ...2250.0004     45.8     22     39GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
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