Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR146C
Length:
347
Number of sequences:
5887
Description:
YMR146C TIF34 SGDID:S000004754, Chr XIII from 558524-557481, Genome Release 64-1-1, reverse complement, Verified ORF, "eIF3i subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation; stimulates rate of ribosomal scanning during translation reinitiation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q9UNX4    943   WDR3_HUMAN WD repeat-containing protein 3 OS=...820.88     35.4     29     49GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
332A7EKM8    458   LIS1_SCLS1 Nuclear distribution protein PAC1 ...2293     33.5     22     36GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
333Q4P4R3    1017   HIR1_USTMA Protein HIR1 OS=Ustilago maydis (s...1220.00001     50.8     25     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
334Q9FLX9    473   NLE1_ARATH Notchless protein homolog OS=Arabi...1641.4     34.7     26     42GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
335Q6BVZ3    504   PFS2_DEBHA Polyadenylation factor subunit 2 O...803.8     33.1     24     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
336Q6PFM9    677   WDR48_DANRE WD repeat-containing protein 48 O...2066.7     32.3     19     39GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
337Q8QFR2    1013   HIRA_XENLA Protein HIRA OS=Xenopus laevis (Af...1330.00001     50.8     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
338Q4ICM0    464   LIS1_GIBZE Nuclear distribution protein PAC1 ...2140.74     35.4     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
339Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...791.7     34.3     30     49GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
340C4R6H3    500   LIS1_PICPG Nuclear distribution protein PAC1 ...1280.00001     50.4     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
341O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...1235.9     32.7     25     39GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
342B7FNU7    439   LIS1_PHATC Lissencephaly-1 homolog OS=Phaeoda...758.6     32     29     47GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
343Q9QXL1    1668   KI21B_MOUSE Kinesin-like protein KIF21B OS=Mu...2020.00001     50.8     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
344Q15542    800   TAF5_HUMAN Transcription initiation factor TF...2440.27     37     20     41GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005669; C:transcription factor TFIID complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0016573; P:histone acetylation; IDA:GOC.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
345P38011    319   GBLP_YEAST Guanine nucleotide-binding protein...877.9     32     26     49GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
GO:0001965; F:G-protein alpha-subunit binding; IPI:SGD.::GO:0005092; F:GDP-dissociation inhibitor activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IMP:SGD.
GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:SGD.::GO:0010255; P:glucose mediated signaling pathway; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD.
346O22212    554   PRP4_ARATH U4/U6 small nuclear ribonucleoprot...441.7     34.3     39     55GO:0016607; C:nuclear speck; IDA:TAIR.
GO:0001709; P:cell fate determination; IMP:TAIR.::GO:0007267; P:cell-cell signaling; IMP:TAIR.::GO:0009560; P:embryo sac egg cell differentiation; IMP:TAIR.::GO:0008380; P:RNA splicing; IEA:InterPro.
347Q05B17    678   WDR48_XENTR WD repeat-containing protein 48 O...2065     32.7     19     39GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
348P16649    713   TUP1_YEAST General transcriptional corepresso...1156.4     32.3     24     40GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
349Q921C3    2304   BRWD1_MOUSE Bromodomain and WD repeat-contain...730.36     36.6     25     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
350Q75AV4    449   PFS2_ASHGO Polyadenylation factor subunit 2 O...2160.00002     50.1     24     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
351C5JD40    473   LIS1_AJEDS Nuclear distribution protein PAC1 ...2270.002     43.9     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
352C5GVJ9    473   LIS1_AJEDR Nuclear distribution protein PAC1 ...2270.002     43.9     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
353P38262    535   SIF2_YEAST SIR4-interacting protein SIF2 OS=S...1730.035     39.7     20     45GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0034967; C:Set3 complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IMP:SGD.::GO:0045835; P:negative regulation of meiosis; IPI:SGD.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:SGD.
354Q6FT96    711   MDV1_CANGA Mitochondrial division protein 1 O...530.21     37.4     30     51GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
355P54311    340   GBB1_RAT Guanine nucleotide-binding protein G...3130.03     39.7     19     35GO:0005834; C:heterotrimeric G-protein complex; TAS:RGD.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0010659; P:cardiac muscle cell apoptotic process; IDA:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.
356P62874    340   GBB1_MOUSE Guanine nucleotide-binding protein...3130.03     39.7     19     35GO:0005834; C:heterotrimeric G-protein complex; IPI:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; IDA:MGI.::GO:0008283; P:cell proliferation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0050909; P:sensory perception of taste; IDA:MGI.
357P62873    340   GBB1_HUMAN Guanine nucleotide-binding protein...3130.03     39.7     19     35GO:0005834; C:heterotrimeric G-protein complex; IDA:MGI.::GO:0005624; C:membrane fraction; ISS:BHF-UCL.
GO:0003924; F:GTPase activity; IDA:MGI.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; ISS:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; ISS:BHF-UCL.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
358P62872    340   GBB1_CANFA Guanine nucleotide-binding protein...3130.03     39.7     19     35
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
359P62871    340   GBB1_BOVIN Guanine nucleotide-binding protein...3130.03     39.7     19     35GO:0005834; C:heterotrimeric G-protein complex; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; IDA:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.::GO:0071380; P:cellular response to prostaglandin E stimulus; IDA:BHF-UCL.
360P93340    326   GBLP_NICPL Guanine nucleotide-binding protein...820.82     35     29     45
361Q9DC48    579   PRP17_MOUSE Pre-mRNA-processing factor 17 OS=...2700.00002     50.1     22     40GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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