UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR131C

Length:

511

Number of sequences:

5887

Description:

YMR131C RRB1 SGDID:S000004738, Chr XIII from 534698-533163, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
541	Q0UN56	782	ERB1_PHANO Ribosome biogenesis protein ERB1 O...	126	0.21	38.1	29	43	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
542	Q5FVN8	476	WSDU1_RAT WD repeat, SAM and U-box domain-con...	123	0.21	37.7	25	45	GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
543	Q99KN2	339	CIAO1_MOUSE Probable cytosolic iron-sulfur pr...	177	1.5	35	21	41	GO:0071817; C:MMXD complex; ISS:UniProtKB.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI.
									GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:MGI.
544	Q5RBW3	925	CORO7_PONAB Coronin-7 OS=Pongo abelii (Sumatr...	175	2.6	34.7	19	33	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
545	Q6LA54	933	YF48_SCHPO Uncharacterized WD repeat-containi...	152	0.22	38.1	26	40	GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
546	O35142	905	COPB2_RAT Coatomer subunit beta' OS=Rattus no...	112	0.22	38.1	29	46	GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
									GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
547	Q6FVD3	840	HIR1_CANGA Protein HIR1 OS=NRRL Y-65) (Yeast)...	136	0.22	38.1	24	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
548	Q0VBY8	426	DDB2_BOVIN DNA damage-binding protein 2 OS=Bo...	149	0.23	37.7	23	41	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
549	B0W517	425	WDR12_CULQU Ribosome biogenesis protein WDR12...	65	0.23	37.7	28	51	GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
									GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
550	Q0ULF5	1256	SEC31_PHANO Protein transport protein SEC31 O...	128	0.23	38.1	24	41	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
551	A8QB65	433	WDR12_BRUMA Ribosome biogenesis protein WDR12...	139	0.24	37.7	24	42	GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
									GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
552	P26309	610	CDC20_YEAST APC/C activator protein CDC20 OS=...	191	0.24	37.7	23	39	GO:0005680; C:anaphase-promoting complex; IPI:SGD.::GO:0033597; C:mitotic checkpoint complex; IDA:SGD.
									GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
									GO:0051487; P:activation of anaphase-promoting complex activity involved in meiotic cell cycle; IMP:SGD.::GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:SGD.::GO:0007133; P:meiotic anaphase I; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031577; P:spindle checkpoint; IPI:SGD.
553	Q4WT34	453	PRP46_ASPFU Pre-mRNA-splicing factor prp46 OS...	96	0.24	37.7	29	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
554	Q8BH57	676	WDR48_MOUSE WD repeat-containing protein 48 O...	134	0.24	37.7	26	41	GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
555	O94620	340	CWF17_SCHPO Pre-mRNA-splicing factor cwf17 OS...	129	0.25	37.4	28	45	GO:0005681; C:spliceosomal complex; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
556	Q8YTC2	1258	Y2800_NOSS1 Uncharacterized WD repeat-contain...	124	4.4	33.9	24	44
									GO:0043531; F:ADP binding; IEA:InterPro.
									GO:0006952; P:defense response; IEA:InterPro.
557	P93563	377	GBB_SOLTU Guanine nucleotide-binding protein ...	107	0.29	37.4	24	49
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
558	Q54Y96	530	SMU1_DICDI WD40 repeat-containing protein smu...	120	2.1	34.7	29	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
559	Q7ZW33	517	UTP15_DANRE U3 small nucleolar RNA-associated...	258	0.26	37.7	22	38	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
560	Q8NHV4	660	NEDD1_HUMAN Protein NEDD1 OS=Homo sapiens (Hu...	99	0.99	35.8	28	41	GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
561	Q3TWF6	657	WDR70_MOUSE WD repeat-containing protein 70 O...	116	0.58	36.6	26	43
562	C7GV13	1342	RTC1_YEAS2 Restriction of telomere capping pr...	156	0.26	37.7	22	37	GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
563	Q08281	1341	RTC1_YEAST Restriction of telomere capping pr...	156	0.26	37.7	22	37	GO:0097042; C:extrinsic to fungal-type vacuolar membrane; IDA:SGD.::GO:0035859; C:Seh1-associated complex; IDA:SGD.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
564	Q53HC9	387	TSSC1_HUMAN Protein TSSC1 OS=Homo sapiens (Hu...	286	0.27	37.4	22	37
565	B3LIS9	1342	RTC1_YEAS1 Restriction of telomere capping pr...	156	0.27	37.7	22	37	GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
566	Q9UM11	496	FZR_HUMAN Fizzy-related protein homolog OS=Ho...	243	7	33.1	23	41	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0045732; P:positive regulation of protein catabolic process; IGI:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; TAS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
567	B4LQ21	411	LIS1_DROVI Lissencephaly-1 homolog OS=Drosoph...	112	3.3	33.9	27	46	GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
568	Q3ULA2	605	FBW1A_MOUSE F-box/WD repeat-containing protei...	122	0.27	37.7	27	42	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
									GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
									GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
569	A6ZN74	1335	RTC1_YEAS7 Restriction of telomere capping pr...	156	0.27	37.7	22	37	GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
570	Q09715	614	TUP11_SCHPO Transcriptional repressor tup11 O...	38	2.2	34.7	45	68	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IGI:PomBase.
									GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006342; P:chromatin silencing; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
571	P31146	461	COR1A_HUMAN Coronin-1A OS=Homo sapiens (Human...	92	0.7	36.2	28	43	GO:0005884; C:actin filament; IDA:UniProtKB.::GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001891; C:phagocytic cup; IDA:UniProtKB.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
									GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
									GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.::GO:0045087; P:innate immune response; NAS:UniProtKB.::GO:0030595; P:leukocyte chemotaxis; IBA:RefGenome.::GO:0051126; P:negative regulation of actin nucleation; IDA:UniProtKB.::GO:0001845; P:phagolysosome assembly; IMP:UniProtKB.::GO:0050918; P:positive chemotaxis; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IBA:RefGenome.::GO:0032796; P:uropod organization; IBA:RefGenome.

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