Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR109W
Length:
1219
Number of sequences:
5887
Description:
YMR109W MYO5 SGDID:S000004715, Chr XIII from 486587-490246, Genome Release 64-1-1, Verified ORF, "One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q9TW28    1737   MYOM_DICDI Myosin-M heavy chain OS=Dictyostel...2060.00000003     62.4     23     46GO:0042995; C:cell projection; IDA:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; ISS:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0016887; F:ATPase activity; ISS:dictyBase.::GO:0000146; F:microfilament motor activity; ISS:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:dictyBase.
GO:0006972; P:hyperosmotic response; IMP:dictyBase.::GO:0006971; P:hypotonic response; IMP:dictyBase.::GO:0031268; P:pseudopodium organization; IMP:dictyBase.::GO:0035020; P:regulation of Rac protein signal transduction; IDA:dictyBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
212Q86AC8    3446   MYOG_DICDI Myosin-G heavy chain OS=Dictyostel...1660.33     39.3     25     42GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
213Q9Y6X6    1858   MYO16_HUMAN Unconventional myosin-XVI OS=Homo...1950.00000000001     73.2     28     47GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; IDA:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC.
GO:0051015; F:actin filament binding; ISS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0021549; P:cerebellum development; ISS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:HGNC.
214Q9ERC1    1912   MYO16_RAT Unconventional myosin-XVI OS=Rattus...1710.0000000001     70.1     29     49GO:0005829; C:cytosol; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:HGNC.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0016459; C:myosin complex; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0005886; C:plasma membrane; IDA:HGNC.::GO:0005625; C:soluble fraction; IDA:HGNC.
GO:0003779; F:actin binding; IDA:RGD.::GO:0051015; F:actin filament binding; IDA:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
GO:0021549; P:cerebellum development; IEP:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IDA:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IDA:HGNC.
215Q5DU14    1919   MYO16_MOUSE Unconventional myosin-XVI OS=Mus ...1950.0000000000004     78.2     29     45GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; ISS:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC.
GO:0051015; F:actin filament binding; ISS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0021549; P:cerebellum development; ISS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:HGNC.
216P10676    1501   NINAC_DROME Neither inactivation nor afterpot...6684e-55     214     26     46GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016027; C:inaD signaling complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0042385; C:myosin III complex; NAS:FlyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IMP:FlyBase.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; IDA:FlyBase.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase.
GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:FlyBase.::GO:0007010; P:cytoskeleton organization; IMP:FlyBase.::GO:0016059; P:deactivation of rhodopsin mediated signaling; IMP:FlyBase.::GO:0033227; P:dsRNA transport; IMP:FlyBase.::GO:0006886; P:intracellular protein transport; IMP:FlyBase.
217Q4P9K9    2005   CHS8_USTMA Chitin synthase 8 OS=Ustilago mayd...541.4     37     30     54GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004100; F:chitin synthase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.
218P04461    736   MYH7_RABIT Myosin-7 OS=Oryctolagus cuniculus ...3949e-46     181     32     49GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
219Q92614    2054   MY18A_HUMAN Unconventional myosin-XVIIIa OS=H...1221.1     37.4     29     48GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008094; F:DNA-dependent ATPase activity; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0006259; P:DNA metabolic process; IEA:InterPro.
220Q9JMH9    2050   MY18A_MOUSE Unconventional myosin-XVIIIa OS=M...1220.67     38.1     30     48GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
221Q8IUG5    2567   MY18B_HUMAN Unconventional myosin-XVIIIb OS=H...4522e-28     128     25     44GO:0005634; C:nucleus; IDA:HPA.::GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
222Q96JP2    1530   MY15B_HUMAN Putative unconventional myosin-XV...2952e-16     89     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro.
223P43069    1333   CDC25_CANAL Cell division control protein 25 ...1150.00002     52.8     35     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:CGD.
GO:0019933; P:cAMP-mediated signaling; IMP:CGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071333; P:cellular response to glucose stimulus; IMP:CGD.::GO:0030447; P:filamentous growth; IMP:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IGI:CGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
224P38822    633   BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere...980.0004     48.5     36     47GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
225Q555L8    389   Y4695_DICDI SH3 and FCH domain-containing pro...720.0008     47     38     54
226Q5ZLR6    764   ARHG6_CHICK Rho guanine nucleotide exchange f...1110.006     44.7     29     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
227Q8IVI9    506   NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ...840.006     44.3     32     49GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
228Q12163    236   NBP2_YEAST NAP1-binding protein 2 OS=Saccharo...630.009     42.7     35     57GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; TAS:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006972; P:hyperosmotic response; IPI:SGD.::GO:0006469; P:negative regulation of protein kinase activity; IDA:SGD.::GO:0009408; P:response to heat; IMP:SGD.
229Q9QY53    687   NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M...480.018     43.1     38     65GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB.
230Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...830.023     42.7     31     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
231Q15052    776   ARHG6_HUMAN Rho guanine nucleotide exchange f...550.023     42.7     36     58GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
232Q8K4I3    771   ARHG6_MOUSE Rho guanine nucleotide exchange f...550.027     42.4     36     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
233Q6YKA8    211   DRK_DROSI Protein E(sev)2B OS=Drosophila simu...610.046     40.4     34     56GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
234Q08012    211   DRK_DROME Protein enhancer of sevenless 2B OS...610.046     40.4     34     56GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.
235O77774    392   NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos...580.051     41.2     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
236Q9CX99    217   GRAP_MOUSE GRB2-related adapter protein OS=Mu...650.053     40.4     32     54
237Q14155    803   ARHG7_HUMAN Rho guanine nucleotide exchange f...670.053     41.6     36     49GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
238Q38953    1168   DHX8_ARATH Probable pre-mRNA-splicing factor ...950.067     41.2     29     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
239Q7SIG6    958   ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe...1080.075     41.2     32     48GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
240Q6GUF4    550   FBP1L_XENTR Formin-binding protein 1-like OS=...1210.12     40     26     45GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
241Q6NRD3    826   SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...808.5     34.3     30     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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