Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR108W
Length:
687
Number of sequences:
5887
Description:
YMR108W ILV2 SGDID:S000004714, Chr XIII from 484084-486147, Genome Release 64-1-1, Verified ORF, "Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q54DA9    580   HACL1_DICDI Probable 2-hydroxyacyl-CoA lyase ...5082e-26     118     22     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
92P66946    547   ILVG_MYCTU Putative acetolactate synthase lar...5652e-26     117     24     41
GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; ISS:UniProtKB.::GO:0009099; P:valine biosynthetic process; ISS:UniProtKB.
93P66947    547   ILVG_MYCBO Probable acetolactate synthase OS=...5652e-26     117     24     41
GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
94B2TJ86    643   IOLD_CLOBB 3D-(3,5/4)-trihydroxycyclohexane-1...6164e-26     117     23     42
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
95A1L0T0    632   ILVBL_HUMAN Acetolactate synthase-like protei...5685e-26     117     22     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
96Q8BU33    632   ILVBL_MOUSE Acetolactate synthase-like protei...5601e-25     115     23     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
97Q898E8    644   IOLD_CLOTE 3D-(3,5/4)-trihydroxycyclohexane-1...6193e-24     111     24     43
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
98Q6DDK5    649   ILVBL_XENLA Acetolactate synthase-like protei...5502e-22     105     24     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
99P51853    563   BZNB_PSEFL Benzaldehyde lyase OS=Pseudomonas ...5801e-21     103     24     42
GO:0047695; F:benzoin aldolase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
100Q9P7P6    572   PDC3_SCHPO Probable pyruvate decarboxylase C1...5736e-20     97.8     22     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009063; P:cellular amino acid catabolic process; ISS:PomBase.::GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.
101O61856    640   ILVBL_CAEEL Acetolactate synthase-like protei...5152e-19     95.9     24     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
102Q9Y7M1    568   YGK4_SCHPO Putative 2-hydroxyacyl-CoA lyase O...5883e-19     95.5     23     43GO:0005829; C:cytosol; IDA:PomBase.
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
103Q92345    569   PDC2_SCHPO Probable pyruvate decarboxylase C1...5932e-18     93.2     22     41
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009063; P:cellular amino acid catabolic process; ISS:PomBase.::GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.
104P83779    567   PDC1_CANAL Pyruvate decarboxylase OS=Candida ...5086e-18     91.7     24     43GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030446; C:hyphal cell wall; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD.::GO:0005625; C:soluble fraction; IDA:CGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
105P23234    552   DCIP_ENTCL Indole-3-pyruvate decarboxylase OS...5747e-18     91.3     24     39
GO:0047434; F:indolepyruvate decarboxylase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
106P10343    396   YI42_PSEAY Uncharacterized 42.6 kDa protein i...3782e-17     88.6     22     42
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
107P51852    545   DCIP_AZOBR Indole-3-pyruvate decarboxylase OS...5585e-17     88.6     22     38
GO:0047434; F:indolepyruvate decarboxylase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
108P39994    560   YEC0_YEAST Putative 2-hydroxyacyl-CoA lyase O...5092e-16     86.3     22     43GO:0005737; C:cytoplasm; IDA:SGD.
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
109Q2UKV4    570   PDC_ASPOR Pyruvate decarboxylase OS=Aspergill...5743e-16     85.9     24     41
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
110P06169    563   PDC1_YEAST Pyruvate decarboxylase isozyme 1 O...5133e-16     85.9     25     40GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IDA:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0019655; P:glucose catabolic process to ethanol; IDA:SGD.::GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006090; P:pyruvate metabolic process; IDA:SGD.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.
111P16467    563   PDC5_YEAST Pyruvate decarboxylase isozyme 2 O...5123e-16     85.9     25     41GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IDA:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0019655; P:glucose catabolic process to ethanol; IDA:SGD.::GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006090; P:pyruvate metabolic process; IDA:SGD.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.
112P34734    564   PDC_HANUV Pyruvate decarboxylase OS=Hansenias...5380.000000000000002     83.6     23     41
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
113Q09737    571   PDC1_SCHPO Putative pyruvate decarboxylase C1...5040.000000000000002     83.6     22     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; ISS:PomBase.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0000949; P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway; ISS:PomBase.::GO:0019655; P:glucose catabolic process to ethanol; ISS:PomBase.::GO:0006090; P:pyruvate metabolic process; ISS:PomBase.
114Q6FJA3    564   PDC1_CANGA Pyruvate decarboxylase OS=NRRL Y-6...5820.000000000000002     83.2     24     40
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
115P26263    563   PDC6_YEAST Pyruvate decarboxylase isozyme 3 O...5120.000000000000002     83.2     24     41GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IMP:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0006067; P:ethanol metabolic process; IMP:SGD.::GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.
116Q12629    563   PDC1_KLULA Pyruvate decarboxylase OS=1267 / N...5080.000000000000003     82.8     24     41
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
117Q742Q2    563   KDC_MYCPA Alpha-keto-acid decarboxylase OS=My...5020.000000000000006     82     25     38
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
118A0QBE6    563   KDC_MYCA1 Alpha-keto-acid decarboxylase OS=My...5020.000000000000007     81.6     25     38
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
119A1BI74    587   MEND_CHLPD 2-succinyl-5-enolpyruvyl-6-hydroxy...5780.00000000000002     80.1     23     40
GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW.
120Q9CBD6    569   KDC_MYCLE Alpha-keto-acid decarboxylase OS=My...5050.00000000000006     78.6     24     40
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
121O53865    560   KDC_MYCTU Alpha-keto-acid decarboxylase OS=My...5050.00000000000009     78.2     26     41GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
records
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