Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR104C
Length:
677
Number of sequences:
5887
Description:
YMR104C YPK2 SGDID:S000004710, Chr XIII from 475453-473420, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase with similarity to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
751P62343    524   CDPK1_PLAFK Calcium-dependent protein kinase ...2584e-27     119     30     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
752P62344    524   CDPK1_PLAF7 Calcium-dependent protein kinase ...2584e-27     119     30     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
753Q2TA25    602   PLK1_BOVIN Serine/threonine-protein kinase PL...2714e-27     120     27     48GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
754Q8IBS5    528   CDPK4_PLAF7 Calcium-dependent protein kinase ...2474e-27     119     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
755Q0KL02    3102   TRIO_MOUSE Triple functional domain protein O...2754e-27     122     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
756A1A5Q6    654   SMK_RAT Sperm motility kinase OS=Rattus norve...2515e-27     120     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
757O22042    651   M3K3_ARATH Mitogen-activated protein kinase k...2625e-27     120     30     50GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.
758Q38873    535   CDPK7_ARATH Calcium-dependent protein kinase ...2866e-27     119     27     51GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
759O49717    554   CDPKF_ARATH Calcium-dependent protein kinase ...2846e-27     119     28     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
760Q9SL76    1094   P2C19_ARATH Protein phosphatase 2C and cyclic...2867e-27     120     27     47GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.
761P43565    1770   RIM15_YEAST Serine/threonine-protein kinase R...1461e-21     104     36     57GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:SGD.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0001324; P:age-dependent response to oxidative stress involved in chronological cell aging; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0040020; P:regulation of meiosis; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
762Q9R012    682   PLK2_RAT Serine/threonine-protein kinase PLK2...2687e-27     120     28     48GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; IDA:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; IDA:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
763Q9H4B4    646   PLK3_HUMAN Serine/threonine-protein kinase PL...2728e-27     119     27     45GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007113; P:endomitotic cell cycle; TAS:UniProtKB.::GO:0071779; P:G1/S transition checkpoint; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0090166; P:Golgi disassembly; IDA:UniProtKB.::GO:0071780; P:mitotic cell cycle G2/M transition checkpoint; TAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; IDA:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB.::GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; IMP:UniProtKB.
764Q94CU5    943   NEK5_ORYSJ Serine/threonine-protein kinase Ne...2849e-27     120     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
765P38692    1080   KIC1_YEAST Serine/threonine-protein kinase KI...3029e-27     120     30     46GO:0005933; C:cellular bud; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0000902; P:cell morphogenesis; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.
766P53351    682   PLK2_MOUSE Serine/threonine-protein kinase PL...2679e-27     119     27     47GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; IMP:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
767Q9NYY3    685   PLK2_HUMAN Serine/threonine-protein kinase PL...2689e-27     119     28     48GO:0005814; C:centriole; IDA:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; IDA:UniProtKB.
768Q5R4L1    685   PLK2_PONAB Serine/threonine-protein kinase PL...2689e-27     119     28     48GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
769Q9ZV15    583   CDPKK_ARATH Calcium-dependent protein kinase ...2671e-26     119     27     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
770O75962    3097   TRIO_HUMAN Triple functional domain protein O...2421e-26     120     31     52GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
771Q9URY1    672   PPK16_SCHPO Serine/threonine-protein kinase p...3291e-26     119     29     49GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase.
772Q9GM70    397   ST17A_RABIT Serine/threonine-protein kinase 1...2901e-26     116     29     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; ISS:UniProtKB.
773Q61241    365   TSSK1_MOUSE Testis-specific serine/threonine-...2591e-26     115     32     50GO:0001669; C:acrosomal vesicle; TAS:UniProtKB.::GO:0019861; C:flagellum; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; IMP:UniProtKB.
774O61267    476   LOK_DROME Ovarian-specific serine/threonine-p...2681e-26     117     29     50GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.
775P62345    528   CDPK4_PLABA Calcium-dependent protein kinase ...2471e-26     117     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
776Q94A06    354   M2K1_ARATH Mitogen-activated protein kinase k...2741e-26     115     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0042742; P:defense response to bacterium; IDA:TAIR.::GO:0009814; P:defense response, incompatible interaction; IGI:TAIR.::GO:0042542; P:response to hydrogen peroxide; IDA:TAIR.::GO:0002237; P:response to molecule of bacterial origin; IDA:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.
777Q9P289    416   MST4_HUMAN Serine/threonine-protein kinase MS...2751e-26     116     31     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
778Q7RJG2    528   CDPK4_PLAYO Calcium-dependent protein kinase ...2471e-26     117     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
779Q54EY4    562   DST3_DICDI Serine/threonine-protein kinase ds...2881e-26     118     29     49GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
780Q06850    610   CDPK1_ARATH Calcium-dependent protein kinase ...2672e-26     118     28     53GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
781Q9N2L7    632   PLK2_CAEEL Serine/threonine-protein kinase pl...2732e-26     118     28     48GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0060631; P:regulation of meiosis I; IMP:WormBase.
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