rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 86 | 0.096 | 39.7 | 28 | 51 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 32 | Q498M4 | 334 | WDR5_RAT WD repeat-containing protein 5 OS=Ra... | 86 | 0.11 | 39.3 | 28 | 51 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 86 | 0.11 | 39.3 | 28 | 51 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 86 | 0.11 | 39.3 | 28 | 51 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 35 | Q6FVD3 | 840 | HIR1_CANGA Protein HIR1 OS=NRRL Y-65) (Yeast)... | 273 | 0.000002 | 55.5 | 25 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 36 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 86 | 0.061 | 40 | 29 | 51 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 37 | Q7ZVF0 | 416 | POC1A_DANRE POC1 centriolar protein homolog A... | 306 | 0.000002 | 54.7 | 24 | 41 | | | | | | | | | | | | | | | | | | | | | | 38 | P32479 | 840 | HIR1_YEAST Protein HIR1 OS=Saccharomyces cere... | 322 | 0.000002 | 55.1 | 24 | 42 | GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0000417; C:HIR complex; IDA:SGD. | | | | | | | | | | GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; IDA:SGD. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD. | 39 | Q8VBV4 | 629 | FBXW7_MOUSE F-box/WD repeat-containing protei... | 240 | 0.000002 | 54.7 | 23 | 46 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 40 | Q8JZX3 | 405 | POC1A_MOUSE POC1 centriolar protein homolog A... | 301 | 0.000003 | 54.3 | 24 | 39 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 41 | Q93847 | 395 | YZLL_CAEEL Uncharacterized WD repeat-containi... | 213 | 0.024 | 41.6 | 22 | 40 | | | | | | | | | | | | | | | | | | | | | | 42 | P46800 | 329 | GBLP_DICDI Guanine nucleotide-binding protein... | 105 | 0.24 | 38.1 | 31 | 48 | GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | | | | | | | | | | | | 43 | Q74ZN0 | 825 | HIR1_ASHGO Protein HIR1 OS=Y-1056) (Yeast) (E... | 172 | 0.000007 | 53.5 | 26 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | Q8YV57 | 1683 | Y2124_NOSS1 Uncharacterized WD repeat-contain... | 156 | 0.17 | 39.3 | 29 | 43 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 45 | P78706 | 604 | RCO1_NEUCR Transcriptional repressor rco-1 OS... | 185 | 0.005 | 44.3 | 24 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 46 | Q2TBP4 | 407 | POC1A_BOVIN POC1 centriolar protein homolog A... | 301 | 0.00001 | 52.4 | 24 | 39 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 47 | P53622 | 1201 | COPA_YEAST Coatomer subunit alpha OS=Saccharo... | 59 | 0.00001 | 53.1 | 39 | 59 | GO:0030126; C:COPI vesicle coat; IMP:SGD. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD. | 48 | Q17963 | 376 | TG125_CAEEL WD repeat-containing protein tag-... | 42 | 2.2 | 35.4 | 38 | 57 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 49 | Q9BQ87 | 522 | TBL1Y_HUMAN F-box-like/WD repeat-containing p... | 266 | 0.00001 | 52 | 23 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 50 | Q8BHJ5 | 514 | TBL1R_MOUSE F-box-like/WD repeat-containing p... | 260 | 0.00002 | 52 | 23 | 39 | | | | | | | | | | | GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q5I0B9 | 622 | ATG16_XENTR Autophagy-related protein 16 OS=X... | 198 | 0.00002 | 52.4 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 52 | A2CEH0 | 490 | POC1B_DANRE POC1 centriolar protein homolog B... | 298 | 0.00002 | 52 | 22 | 41 | | | | | | | | | | | | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IMP:ZFIN.::GO:0003014; P:renal system process; IMP:ZFIN. | 53 | Q9V3J8 | 361 | WDS_DROME Protein will die slowly OS=Drosophi... | 66 | 0.1 | 39.7 | 32 | 56 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase. | 54 | Q8NBT0 | 407 | POC1A_HUMAN POC1 centriolar protein homolog A... | 303 | 0.00002 | 51.6 | 24 | 39 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 55 | Q9BZK7 | 514 | TBL1R_HUMAN F-box-like/WD repeat-containing p... | 260 | 0.00002 | 51.6 | 23 | 39 | GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 56 | Q5RF51 | 357 | SNR40_PONAB U5 small nuclear ribonucleoprotei... | 215 | 0.00003 | 50.8 | 24 | 44 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 57 | Q96DI7 | 357 | SNR40_HUMAN U5 small nuclear ribonucleoprotei... | 215 | 0.00004 | 50.4 | 24 | 44 | GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005732; C:small nucleolar ribonucleoprotein complex; NAS:UniProtKB.::GO:0005682; C:U5 snRNP; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB. | 58 | P49695 | 742 | PKWA_THECU Probable serine/threonine-protein ... | 175 | 0.001 | 46.2 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | Q95RJ9 | 700 | EBI_DROME F-box-like/WD repeat-containing pro... | 94 | 0.008 | 43.5 | 31 | 45 | GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase. | 60 | Q9D7H2 | 328 | WDR5B_MOUSE WD repeat-containing protein 5B O... | 66 | 0.2 | 38.5 | 32 | 56 | | | | | | | | | | | | | | | | | | | | | | 61 | Q55563 | 1693 | Y163_SYNY3 Uncharacterized WD repeat-containi... | 246 | 0.013 | 43.1 | 21 | 38 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | |