Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR089C
Length:
825
Number of sequences:
5887
Description:
YMR089C YTA12 SGDID:S000004695, Chr XIII from 448086-445609, Genome Release 64-1-1, reverse complement, Verified ORF, "Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40341    825   YTA12_YEAST Mitochondrial respiratory chain c...8250     1699     100     100GO:0005745; C:m-AAA complex; IDA:SGD.::GO:0097002; C:mitochondrial inner boundary membrane; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006461; P:protein complex assembly; IMP:SGD.::GO:0045041; P:protein import into mitochondrial intermembrane space; TAS:SGD.::GO:0006508; P:proteolysis; IMP:SGD.::GO:0006465; P:signal peptide processing; IMP:SGD.
2P39925    761   AFG3_YEAST Mitochondrial respiratory chain co...6380     748     59     74GO:0005745; C:m-AAA complex; IDA:SGD.::GO:0097002; C:mitochondrial inner boundary membrane; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006461; P:protein complex assembly; IMP:SGD.::GO:0045041; P:protein import into mitochondrial intermembrane space; TAS:SGD.::GO:0006508; P:proteolysis; IMP:SGD.::GO:0006465; P:signal peptide processing; IMP:SGD.
3Q9HGM3    773   RCA1_SCHPO Mitochondrial respiratory chain co...6500     686     57     72GO:0005745; C:m-AAA complex; ISS:PomBase.
GO:0005524; F:ATP binding; ISS:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0033108; P:mitochondrial respiratory chain complex assembly; ISS:PomBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0045041; P:protein import into mitochondrial intermembrane space; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase.::GO:0006465; P:signal peptide processing; ISS:PomBase.
4Q2KJI7    805   AFG32_BOVIN AFG3-like protein 2 OS=Bos taurus...6670     676     54     69GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
5Q9Y4W6    797   AFG32_HUMAN AFG3-like protein 2 OS=Homo sapie...6200     674     57     72GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
6Q8JZQ2    802   AFG32_MOUSE AFG3-like protein 2 OS=Mus muscul...5950     673     58     74GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007409; P:axonogenesis; IMP:MGI.::GO:0016265; P:death; IMP:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0021675; P:nerve development; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0060013; P:righting reflex; IMP:MGI.
7Q0DHL4    822   FTSH8_ORYSJ ATP-dependent zinc metalloproteas...6510     668     52     71GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8Q8S2A7    802   FTSH3_ORYSJ ATP-dependent zinc metalloproteas...6350     654     51     71GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9Q8VZI8    813   FTSHA_ARATH ATP-dependent zinc metalloproteas...6090     638     52     72GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10Q84WU8    809   FTSH3_ARATH ATP-dependent zinc metalloproteas...6290     627     52     71GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11Q920A7    789   AFG31_MOUSE AFG3-like protein 1 OS=Mus muscul...5940     619     55     72GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12D0MGU8    697   FTSH_RHOM4 ATP-dependent zinc metalloprotease...5430     570     52     73GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13A6LD25    684   FTSH_PARD8 ATP-dependent zinc metalloprotease...6263e-178     536     47     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14Q3ULF4    781   SPG7_MOUSE Paraplegin OS=Mus musculus (Mouse)...6403e-176     534     46     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008089; P:anterograde axon cargo transport; IMP:MGI.::GO:0007155; P:cell adhesion; TAS:MGI.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; TAS:MGI.
15Q9UQ90    795   SPG7_HUMAN Paraplegin OS=Homo sapiens (Human)...6352e-174     530     47     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; TAS:ProtInc.
16A0LN68    647   FTSH_SYNFM ATP-dependent zinc metalloprotease...6082e-163     496     45     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
17A9BHD3    630   FTSH2_PETMO ATP-dependent zinc metalloproteas...5051e-157     481     49     69GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
18D5H7Z5    686   FTSH1_SALRM ATP-dependent zinc metalloproteas...5152e-157     482     50     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19P73437    628   FTSH4_SYNY3 ATP-dependent zinc metalloproteas...5126e-157     479     49     67GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042651; C:thylakoid membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20B2UE66    714   FTSH_RALPJ ATP-dependent zinc metalloprotease...5102e-156     480     48     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21B8H444    626   FTSH_CAUCN ATP-dependent zinc metalloprotease...5096e-156     476     49     69GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
22Q3B6R3    706   FTSH_PELLD ATP-dependent zinc metalloprotease...5139e-156     479     50     69GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
23P37476    637   FTSH_BACSU ATP-dependent zinc metalloprotease...5109e-155     474     49     69GO:0030428; C:cell septum; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030163; P:protein catabolic process; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0043934; P:sporulation; IMP:UniProtKB.
24Q3JMH0    666   FTSH_BURP1 ATP-dependent zinc metalloprotease...4809e-155     474     51     70GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25Q67JH0    626   FTSH3_SYMTH ATP-dependent zinc metalloproteas...4631e-154     473     53     72GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
26D5D8E3    619   FTSH_SULMD ATP-dependent zinc metalloprotease...5887e-154     471     45     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
27Q7TT47    744   SPG7_RAT Paraplegin OS=Rattus norvegicus (Rat...6407e-153     472     42     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
28A9BJK3    645   FTSH3_PETMO ATP-dependent zinc metalloproteas...5697e-153     469     46     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
29P94304    679   FTSH_BACPE ATP-dependent zinc metalloprotease...5183e-152     468     48     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30B8J992    706   FTSH_ANAD2 ATP-dependent zinc metalloprotease...4972e-151     468     48     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31B1GZK7    631   FTSH_UNCTG ATP-dependent zinc metalloprotease...4987e-151     463     49     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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