rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q06945 | 474 | SOX4_HUMAN Transcription factor SOX-4 OS=Homo... | 65 | 0.5 | 34.3 | 28 | 54 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB. | | | | | | | | | | GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; ISS:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.::GO:0021782; P:glial cell development; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:BHF-UCL.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; ISS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; IMP:UniProtKB.::GO:0002328; P:pro-B cell differentiation; ISS:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021522; P:spinal cord motor neuron differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL. | 272 | A5A763 | 469 | SOX10_PIG Transcription factor SOX-10 OS=Sus ... | 65 | 2.3 | 32.3 | 26 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 273 | Q04888 | 466 | SOX10_MOUSE Transcription factor SOX-10 OS=Mu... | 65 | 2.2 | 32.3 | 26 | 54 | GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0048469; P:cell maturation; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048546; P:digestive tract morphogenesis; IMP:MGI.::GO:0048484; P:enteric nervous system development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IGI:MGI.::GO:0014015; P:positive regulation of gliogenesis; IMP:UniProtKB.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. | 274 | O94900 | 526 | TOX_HUMAN Thymocyte selection-associated high... | 63 | 0.018 | 38.9 | 32 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 275 | Q6IZ48 | 462 | SOX8_TETNG Transcription factor Sox-8 OS=nigr... | 67 | 0.018 | 38.5 | 28 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 276 | Q8IMA8 | 1192 | PANG2_DROME Protein pangolin, isoform J OS=Dr... | 66 | 0.031 | 38.1 | 30 | 55 | GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005667; C:transcription factor complex; IPI:FlyBase. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0019900; F:kinase binding; IPI:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0007507; P:heart development; TAS:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; ISS:UniProtKB.::GO:0007500; P:mesodermal cell fate determination; TAS:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; ISS:UniProtKB.::GO:0072091; P:regulation of stem cell proliferation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IEA:UniProtKB-KW.::GO:0035277; P:spiracle morphogenesis, open tracheal system; ISS:UniProtKB. | 277 | Q06831 | 440 | SOX4_MOUSE Transcription factor SOX-4 OS=Mus ... | 65 | 0.26 | 35 | 29 | 54 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0035910; P:ascending aorta morphogenesis; IMP:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IMP:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0021782; P:glial cell development; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060993; P:kidney morphogenesis; IMP:BHF-UCL.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0002328; P:pro-B cell differentiation; IMP:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL. | 278 | Q8WY36 | 941 | BBX_HUMAN HMG box transcription factor BBX OS... | 71 | 0.062 | 37.4 | 31 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 279 | Q9XT60 | 220 | SRY_CANFA Sex-determining region Y protein OS... | 56 | 0.019 | 38.1 | 32 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 280 | Q04886 | 464 | SOX8_MOUSE Transcription factor SOX-8 OS=Mus ... | 55 | 4.9 | 31.2 | 27 | 55 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; IMP:MGI.::GO:0060018; P:astrocyte fate commitment; IGI:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0048484; P:enteric nervous system development; IMP:UniProtKB.::GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0072289; P:metanephric nephron tubule formation; IGI:MGI.::GO:0061138; P:morphogenesis of a branching epithelium; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IGI:MGI.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0014015; P:positive regulation of gliogenesis; IMP:UniProtKB.::GO:0033690; P:positive regulation of osteoblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010817; P:regulation of hormone levels; IMP:MGI.::GO:0072034; P:renal vesicle induction; IMP:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; IGI:MGI.::GO:0060009; P:Sertoli cell development; IEP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072197; P:ureter morphogenesis; IGI:MGI. | 281 | Q800Q5 | 551 | T7L1B_DANRE Transcription factor 7-like 1-B O... | 49 | 0.33 | 35 | 33 | 61 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome. | | | | | | | | | | GO:0035284; P:brain segmentation; IMP:ZFIN.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0009880; P:embryonic pattern specification; IMP:ZFIN.::GO:0030902; P:hindbrain development; IMP:ZFIN.::GO:0030901; P:midbrain development; IMP:ZFIN.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0021903; P:rostrocaudal neural tube patterning; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 282 | B7ZR65 | 477 | SOX9A_XENLA Transcription factor Sox-9-A OS=X... | 65 | 6.4 | 30.8 | 23 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0051216; P:cartilage development; ISS:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; IMP:UniProtKB.::GO:0043049; P:otic placode formation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 283 | Q03256 | 240 | SRY_CAPHI Sex-determining region Y protein OS... | 65 | 2.1 | 32 | 25 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 284 | Q03257 | 240 | SRY_SHEEP Sex-determining region Y protein OS... | 65 | 1.9 | 32.3 | 25 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 285 | P48434 | 494 | SOX9_CHICK Transcription factor SOX-9 OS=Gall... | 65 | 3 | 32 | 25 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0003170; P:heart valve development; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 286 | Q6DFF5 | 476 | SOX9B_XENLA Transcription factor Sox-9-B OS=X... | 65 | 7.1 | 30.8 | 23 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; ISS:UniProtKB. | | | | | | | | | | GO:0051216; P:cartilage development; ISS:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; ISS:UniProtKB.::GO:0043049; P:otic placode formation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 287 | Q7YRJ7 | 513 | SOX9_CANFA Transcription factor SOX-9 OS=Cani... | 55 | 3.1 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 288 | B3DM43 | 753 | SOX5_XENTR Transcription factor Sox-5 OS=Xeno... | 65 | 0.14 | 36.2 | 25 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 289 | P40640 | 72 | AES6_ALLMI SRY-related protein AES6 OS=Alliga... | 65 | 2.9 | 30 | 25 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 290 | Q04887 | 507 | SOX9_MOUSE Transcription factor SOX-9 OS=Mus ... | 55 | 3.2 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0004672; F:protein kinase activity; IMP:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0060018; P:astrocyte fate commitment; IGI:MGI.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; IMP:MGI.::GO:0001708; P:cell fate specification; IMP:MGI.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0071504; P:cellular response to heparin; IDA:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IDA:MGI.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; IMP:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0003203; P:endocardial cushion morphogenesis; IMP:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; IMP:MGI.::GO:0001837; P:epithelial to mesenchymal transition; IMP:MGI.::GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0003188; P:heart valve formation; IMP:MGI.::GO:0060729; P:intestinal epithelial structure maintenance; IMP:MGI.::GO:0035622; P:intrahepatic bile duct development; IMP:MGI.::GO:0060174; P:limb bud formation; IEP:UniProtKB.::GO:0019100; P:male germ-line sex determination; IMP:MGI.::GO:0030879; P:mammary gland development; IEP:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0002683; P:negative regulation of immune system process; IMP:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0030903; P:notochord development; IEP:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0001503; P:ossification; IEP:UniProtKB.::GO:0030916; P:otic vesicle formation; IMP:MGI.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:MGI.::GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; IMP:MGI.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IMP:MGI.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; IMP:MGI.::GO:0072034; P:renal vesicle induction; IMP:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; IGI:MGI.::GO:0060009; P:Sertoli cell development; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IMP:MGI.::GO:0007283; P:spermatogenesis; IGI:MGI.::GO:0072197; P:ureter morphogenesis; IGI:MGI.::GO:0072190; P:ureter urothelium development; IEP:UniProtKB. | 291 | Q86U86 | 1689 | PB1_HUMAN Protein polybromo-1 OS=Homo sapiens... | 82 | 0.076 | 37 | 29 | 51 | GO:0000228; C:nuclear chromosome; NAS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006338; P:chromatin remodeling; TAS:UniProtKB.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 292 | Q9BG91 | 509 | SOX9_CALJA Transcription factor SOX-9 OS=Call... | 55 | 3.3 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 293 | O18896 | 509 | SOX9_PIG Transcription factor SOX-9 OS=Sus sc... | 55 | 3.2 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 294 | P35710 | 763 | SOX5_MOUSE Transcription factor SOX-5 OS=Mus ... | 65 | 0.15 | 36.2 | 25 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI. | | | | | | | | | | GO:0051216; P:cartilage development; IGI:MGI.::GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0021953; P:central nervous system neuron differentiation; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060164; P:regulation of timing of neuron differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 295 | P61754 | 509 | SOX9_PONPY Transcription factor SOX-9 OS=Pong... | 55 | 3.3 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 296 | P61753 | 509 | SOX9_MACMU Transcription factor SOX-9 OS=Maca... | 55 | 3.3 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 297 | P48436 | 509 | SOX9_HUMAN Transcription factor SOX-9 OS=Homo... | 55 | 3.3 | 32 | 27 | 56 | GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; IMP:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; IDA:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006334; P:nucleosome assembly; IDA:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IEP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IMP:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 298 | P35711 | 763 | SOX5_HUMAN Transcription factor SOX-5 OS=Homo... | 65 | 0.15 | 36.2 | 25 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 299 | Q9Z1J1 | 584 | TF7L1_MOUSE Transcription factor 7-like 1 OS=... | 75 | 0.21 | 35.4 | 33 | 55 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome. | | | | | | | | | | GO:0008595; P:anterior/posterior axis specification, embryo; IMP:MGI.::GO:0048319; P:axial mesoderm morphogenesis; IMP:MGI.::GO:0007420; P:brain development; IBA:RefGenome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0048699; P:generation of neurons; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0046022; P:positive regulation of transcription from RNA polymerase II promoter during mitosis; IDA:MGI.::GO:2000036; P:regulation of stem cell maintenance; IMP:MGI.::GO:0043588; P:skin development; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 300 | Q8BSQ9 | 1634 | PB1_MOUSE Protein polybromo-1 OS=Mus musculus... | 45 | 1.7 | 33.1 | 31 | 56 | GO:0000776; C:kinetochore; IDA:MGI.::GO:0005634; C:nucleus; IC:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0001974; P:blood vessel remodeling; TAS:DFLAT.::GO:0060948; P:cardiac vascular smooth muscle cell development; TAS:DFLAT.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0003349; P:epicardium-derived cardiac endothelial cell differentiation; TAS:DFLAT.::GO:0003007; P:heart morphogenesis; TAS:DFLAT.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001890; P:placenta development; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:DFLAT.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT. | 301 | Q9BH08 | 229 | SRY_CERNI Sex-determining region Y protein OS... | 65 | 0.7 | 33.5 | 25 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |