Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR072W
Length:
183
Number of sequences:
5887
Description:
YMR072W ABF2 SGDID:S000004676, Chr XIII from 411569-412120, Genome Release 64-1-1, Verified ORF, "Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q06945    474   SOX4_HUMAN Transcription factor SOX-4 OS=Homo...650.5     34.3     28     54GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.
GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; ISS:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.::GO:0021782; P:glial cell development; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:BHF-UCL.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; ISS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; IMP:UniProtKB.::GO:0002328; P:pro-B cell differentiation; ISS:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021522; P:spinal cord motor neuron differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
272A5A763    469   SOX10_PIG Transcription factor SOX-10 OS=Sus ...652.3     32.3     26     54GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
273Q04888    466   SOX10_MOUSE Transcription factor SOX-10 OS=Mu...652.2     32.3     26     54GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0048469; P:cell maturation; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048546; P:digestive tract morphogenesis; IMP:MGI.::GO:0048484; P:enteric nervous system development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IGI:MGI.::GO:0014015; P:positive regulation of gliogenesis; IMP:UniProtKB.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
274O94900    526   TOX_HUMAN Thymocyte selection-associated high...630.018     38.9     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
275Q6IZ48    462   SOX8_TETNG Transcription factor Sox-8 OS=nigr...670.018     38.5     28     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
276Q8IMA8    1192   PANG2_DROME Protein pangolin, isoform J OS=Dr...660.031     38.1     30     55GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005667; C:transcription factor complex; IPI:FlyBase.
GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0019900; F:kinase binding; IPI:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.
GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0007507; P:heart development; TAS:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; ISS:UniProtKB.::GO:0007500; P:mesodermal cell fate determination; TAS:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; ISS:UniProtKB.::GO:0072091; P:regulation of stem cell proliferation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IEA:UniProtKB-KW.::GO:0035277; P:spiracle morphogenesis, open tracheal system; ISS:UniProtKB.
277Q06831    440   SOX4_MOUSE Transcription factor SOX-4 OS=Mus ...650.26     35     29     54GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.
GO:0035910; P:ascending aorta morphogenesis; IMP:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IMP:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0021782; P:glial cell development; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060993; P:kidney morphogenesis; IMP:BHF-UCL.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0002328; P:pro-B cell differentiation; IMP:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL.
278Q8WY36    941   BBX_HUMAN HMG box transcription factor BBX OS...710.062     37.4     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
279Q9XT60    220   SRY_CANFA Sex-determining region Y protein OS...560.019     38.1     32     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
280Q04886    464   SOX8_MOUSE Transcription factor SOX-8 OS=Mus ...554.9     31.2     27     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0060612; P:adipose tissue development; IMP:MGI.::GO:0060018; P:astrocyte fate commitment; IGI:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0048484; P:enteric nervous system development; IMP:UniProtKB.::GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0072289; P:metanephric nephron tubule formation; IGI:MGI.::GO:0061138; P:morphogenesis of a branching epithelium; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IGI:MGI.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0014015; P:positive regulation of gliogenesis; IMP:UniProtKB.::GO:0033690; P:positive regulation of osteoblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010817; P:regulation of hormone levels; IMP:MGI.::GO:0072034; P:renal vesicle induction; IMP:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; IGI:MGI.::GO:0060009; P:Sertoli cell development; IEP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072197; P:ureter morphogenesis; IGI:MGI.
281Q800Q5    551   T7L1B_DANRE Transcription factor 7-like 1-B O...490.33     35     33     61GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome.
GO:0035284; P:brain segmentation; IMP:ZFIN.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0009880; P:embryonic pattern specification; IMP:ZFIN.::GO:0030902; P:hindbrain development; IMP:ZFIN.::GO:0030901; P:midbrain development; IMP:ZFIN.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0021903; P:rostrocaudal neural tube patterning; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
282B7ZR65    477   SOX9A_XENLA Transcription factor Sox-9-A OS=X...656.4     30.8     23     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0051216; P:cartilage development; ISS:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; IMP:UniProtKB.::GO:0043049; P:otic placode formation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
283Q03256    240   SRY_CAPHI Sex-determining region Y protein OS...652.1     32     25     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
284Q03257    240   SRY_SHEEP Sex-determining region Y protein OS...651.9     32.3     25     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
285P48434    494   SOX9_CHICK Transcription factor SOX-9 OS=Gall...653     32     25     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0003170; P:heart valve development; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
286Q6DFF5    476   SOX9B_XENLA Transcription factor Sox-9-B OS=X...657.1     30.8     23     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; ISS:UniProtKB.
GO:0051216; P:cartilage development; ISS:UniProtKB.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; ISS:UniProtKB.::GO:0043049; P:otic placode formation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
287Q7YRJ7    513   SOX9_CANFA Transcription factor SOX-9 OS=Cani...553.1     32     27     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
288B3DM43    753   SOX5_XENTR Transcription factor Sox-5 OS=Xeno...650.14     36.2     25     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
289P40640    72   AES6_ALLMI SRY-related protein AES6 OS=Alliga...652.9     30     25     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
290Q04887    507   SOX9_MOUSE Transcription factor SOX-9 OS=Mus ...553.2     32     27     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0004672; F:protein kinase activity; IMP:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0060018; P:astrocyte fate commitment; IGI:MGI.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; IMP:MGI.::GO:0001708; P:cell fate specification; IMP:MGI.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0071504; P:cellular response to heparin; IDA:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IDA:MGI.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; IMP:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0003203; P:endocardial cushion morphogenesis; IMP:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; IMP:MGI.::GO:0001837; P:epithelial to mesenchymal transition; IMP:MGI.::GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0003188; P:heart valve formation; IMP:MGI.::GO:0060729; P:intestinal epithelial structure maintenance; IMP:MGI.::GO:0035622; P:intrahepatic bile duct development; IMP:MGI.::GO:0060174; P:limb bud formation; IEP:UniProtKB.::GO:0019100; P:male germ-line sex determination; IMP:MGI.::GO:0030879; P:mammary gland development; IEP:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0002683; P:negative regulation of immune system process; IMP:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0030903; P:notochord development; IEP:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0001503; P:ossification; IEP:UniProtKB.::GO:0030916; P:otic vesicle formation; IMP:MGI.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:MGI.::GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; IMP:MGI.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IMP:MGI.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; IMP:MGI.::GO:0072034; P:renal vesicle induction; IMP:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; IGI:MGI.::GO:0060009; P:Sertoli cell development; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IMP:MGI.::GO:0007283; P:spermatogenesis; IGI:MGI.::GO:0072197; P:ureter morphogenesis; IGI:MGI.::GO:0072190; P:ureter urothelium development; IEP:UniProtKB.
291Q86U86    1689   PB1_HUMAN Protein polybromo-1 OS=Homo sapiens...820.076     37     29     51GO:0000228; C:nuclear chromosome; NAS:UniProtKB.
GO:0003682; F:chromatin binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006338; P:chromatin remodeling; TAS:UniProtKB.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
292Q9BG91    509   SOX9_CALJA Transcription factor SOX-9 OS=Call...553.3     32     27     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
293O18896    509   SOX9_PIG Transcription factor SOX-9 OS=Sus sc...553.2     32     27     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
294P35710    763   SOX5_MOUSE Transcription factor SOX-5 OS=Mus ...650.15     36.2     25     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0051216; P:cartilage development; IGI:MGI.::GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0021953; P:central nervous system neuron differentiation; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060164; P:regulation of timing of neuron differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
295P61754    509   SOX9_PONPY Transcription factor SOX-9 OS=Pong...553.3     32     27     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
296P61753    509   SOX9_MACMU Transcription factor SOX-9 OS=Maca...553.3     32     27     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; ISS:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
297P48436    509   SOX9_HUMAN Transcription factor SOX-9 OS=Homo...553.3     32     27     56GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.::GO:0001502; P:cartilage condensation; ISS:UniProtKB.::GO:0001708; P:cell fate specification; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; IMP:UniProtKB.::GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; IDA:UniProtKB.::GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0001942; P:hair follicle development; ISS:UniProtKB.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.::GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.::GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.::GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006334; P:nucleosome assembly; IDA:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IEP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IMP:UniProtKB.::GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.::GO:0072034; P:renal vesicle induction; ISS:UniProtKB.::GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
298P35711    763   SOX5_HUMAN Transcription factor SOX-5 OS=Homo...650.15     36.2     25     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
299Q9Z1J1    584   TF7L1_MOUSE Transcription factor 7-like 1 OS=...750.21     35.4     33     55GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome.
GO:0008595; P:anterior/posterior axis specification, embryo; IMP:MGI.::GO:0048319; P:axial mesoderm morphogenesis; IMP:MGI.::GO:0007420; P:brain development; IBA:RefGenome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0048699; P:generation of neurons; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0046022; P:positive regulation of transcription from RNA polymerase II promoter during mitosis; IDA:MGI.::GO:2000036; P:regulation of stem cell maintenance; IMP:MGI.::GO:0043588; P:skin development; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
300Q8BSQ9    1634   PB1_MOUSE Protein polybromo-1 OS=Mus musculus...451.7     33.1     31     56GO:0000776; C:kinetochore; IDA:MGI.::GO:0005634; C:nucleus; IC:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001974; P:blood vessel remodeling; TAS:DFLAT.::GO:0060948; P:cardiac vascular smooth muscle cell development; TAS:DFLAT.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0003349; P:epicardium-derived cardiac endothelial cell differentiation; TAS:DFLAT.::GO:0003007; P:heart morphogenesis; TAS:DFLAT.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001890; P:placenta development; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:DFLAT.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.
301Q9BH08    229   SRY_CERNI Sex-determining region Y protein OS...650.7     33.5     25     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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