Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR070W
Length:
490
Number of sequences:
5887
Description:
YMR070W MOT3 SGDID:S000004674, Chr XIII from 409154-410626, Genome Release 64-1-1, Verified ORF, "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes; can form the [MOT3+] prion"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q63ZV0    521   INSM1_MOUSE Insulinoma-associated protein 1 O...260.59     36.2     42     81GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003323; P:type B pancreatic cell development; IMP:MGI.
512Q05215    486   EGR4_HUMAN Early growth response protein 4 OS...491     35.4     39     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
513P26634    62   EGR2_CERTH E3 SUMO-protein ligase EGR2 OS=Cer...330.66     33.5     33     58GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
514Q9VJN5    470   WEK_DROME Zinc finger protein weckle OS=Droso...440.6     36.2     36     55GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007311; P:maternal specification of dorsal/ventral axis, oocyte, germ-line encoded; IMP:FlyBase.::GO:0008063; P:Toll signaling pathway; IMP:FlyBase.
515Q8R0T2    568   ZN768_MOUSE Zinc finger protein 768 OS=Mus mu...491.5     35     31     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
516Q3U133    652   ZN746_MOUSE Zinc finger protein 746 OS=Mus mu...481.2     35.4     31     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0010941; P:regulation of cell death; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
517Q9V5M3    878   LOLA6_DROME Longitudinals lacking protein, is...400.64     36.6     53     60GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019730; P:antimicrobial humoral response; IMP:FlyBase.::GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0048854; P:brain morphogenesis; IMP:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0031987; P:locomotion involved in locomotory behavior; IMP:FlyBase.::GO:0045476; P:nurse cell apoptotic process; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0007464; P:R3/R4 cell fate commitment; IMP:FlyBase.::GO:0045467; P:R7 cell development; IMP:FlyBase.::GO:0001964; P:startle response; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
518P17035    718   ZNF28_HUMAN Zinc finger protein 28 OS=Homo sa...348.9     32.7     41     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
519Q8VHT8    363   TF3A_RAT Transcription factor IIIA OS=Rattus ...640.64     36.2     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
520P17041    273   ZNF32_HUMAN Zinc finger protein 32 OS=Homo sa...670.65     35.8     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
521Q6NUN9    644   ZN746_HUMAN Zinc finger protein 746 OS=Homo s...481.3     35.4     31     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0010941; P:regulation of cell death; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
522Q8BU00    419   IKZF5_MOUSE Zinc finger protein Pegasus OS=Mu...522.7     34.3     29     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
523Q96MM3    310   ZFP42_HUMAN Zinc finger protein 42 homolog OS...560.66     35.8     38     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008585; P:female gonad development; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0007126; P:meiosis; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
524Q2EI21    1501   RESTA_XENLA RE1-silencing transcription facto...346.8     33.1     38     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
525Q2TB10    664   ZN800_HUMAN Zinc finger protein 800 OS=Homo s...690.67     36.2     26     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
526E9PZZ1    754   PRD13_MOUSE PR domain zinc finger protein 13 ...500.67     36.2     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0022008; P:neurogenesis; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
527Q9H5V7    419   IKZF5_HUMAN Zinc finger protein Pegasus OS=Ho...522.7     34.3     29     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
528Q08705    728   CTCF_CHICK Transcriptional repressor CTCF OS=...535.5     33.5     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
529P10075    376   GLI4_HUMAN Zinc finger protein GLI4 OS=Homo s...710.93     35.4     28     51GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
530Q61164    736   CTCF_MOUSE Transcriptional repressor CTCF OS=...536.2     33.1     30     51GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0009048; P:dosage compensation by inactivation of X chromosome; TAS:MGI.::GO:0010216; P:maintenance of DNA methylation; IMP:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IDA:MGI.::GO:0035065; P:regulation of histone acetylation; IMP:UniProtKB.::GO:0031060; P:regulation of histone methylation; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
531Q01101    510   INSM1_HUMAN Insulinoma-associated protein 1 O...260.71     36.2     42     81GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
532Q7Z7K2    595   ZN467_HUMAN Zinc finger protein 467 OS=Homo s...525.3     33.5     35     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
533O75626    825   PRDM1_HUMAN PR domain zinc finger protein 1 O...493.6     33.9     33     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
534Q6YND2    615   ZN653_MOUSE Zinc finger protein 653 OS=Mus mu...441.8     35     39     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
535P49711    727   CTCF_HUMAN Transcriptional repressor CTCF OS=...536.2     33.1     30     51GO:0000775; C:chromosome, centromeric region; IDA:UniProtKB.::GO:0000793; C:condensed chromosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.
GO:0043035; F:chromatin insulator sequence binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:UniProtKB.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0016584; P:nucleosome positioning; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0070602; P:regulation of centromeric sister chromatid cohesion; NAS:UniProtKB.::GO:0040030; P:regulation of molecular function, epigenetic; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
536Q8NAM6    433   ZSCA4_HUMAN Zinc finger and SCAN domain-conta...590.75     35.8     29     53GO:0000784; C:nuclear chromosome, telomeric region; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
537A1YFX5    433   ZSCA4_PANPA Zinc finger and SCAN domain-conta...590.76     35.8     29     53GO:0000784; C:nuclear chromosome, telomeric region; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
538P49953    239   WT1_SMIMA Wilms tumor protein homolog OS=Smin...516     32.7     33     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0008406; P:gonad development; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
539Q0VEE6    662   ZN800_MOUSE Zinc finger protein 800 OS=Mus mu...690.78     36.2     26     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
540Q9R1D1    737   CTCF_RAT Transcriptional repressor CTCF OS=Ra...536.4     33.1     30     51GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
541P18730    420   ZG58_XENLA Gastrula zinc finger protein XlCGF...790.79     35.8     29     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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