Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR070W
Length:
490
Number of sequences:
5887
Description:
YMR070W MOT3 SGDID:S000004674, Chr XIII from 409154-410626, Genome Release 64-1-1, Verified ORF, "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes; can form the [MOT3+] prion"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q870A3    609   PACC_FUSOX pH-response transcription factor p...320.086     39.3     44     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
362D3ZUU2    707   GZF1_RAT GDNF-inducible zinc finger protein 1...750.087     39.3     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
363Q14526    733   HIC1_HUMAN Hypermethylated in cancer 1 protei...483.8     33.9     31     52GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
364Q00899    414   TYY1_MOUSE Transcriptional repressor protein ...570.09     38.9     37     53GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0031519; C:PcG protein complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0048593; P:camera-type eye morphogenesis; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051276; P:chromosome organization; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0006403; P:RNA localization; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
365P10074    688   ZBT48_HUMAN Zinc finger and BTB domain-contai...555.8     33.1     33     49GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
366P26633    62   EGR2_CRIGR E3 SUMO-protein ligase EGR2 OS=Cri...330.32     34.7     33     61GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
367Q9VQU9    744   BOWEL_DROME Protein bowel OS=Drosophila melan...456.8     33.1     31     53GO:0005634; C:nucleus; ISS:FlyBase.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048617; P:embryonic foregut morphogenesis; IMP:UniProtKB.::GO:0048619; P:embryonic hindgut morphogenesis; IMP:UniProtKB.::GO:0016348; P:imaginal disc-derived leg joint morphogenesis; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007366; P:periodic partitioning by pair rule gene; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007362; P:terminal region determination; IMP:UniProtKB.::GO:0035220; P:wing disc development; IMP:FlyBase.
368Q5R633    688   ZBT48_PONAB Zinc finger and BTB domain-contai...556     33.1     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
369Q99LH4    468   ZN672_MOUSE Zinc finger protein 672 OS=Mus mu...1110.1     38.9     32     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
370Q9JLZ6    619   HIC2_MOUSE Hypermethylated in cancer 2 protei...486.4     33.1     29     54GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
371Q7TS63    1237   ZFAT_MOUSE Zinc finger protein ZFAT OS=Mus mu...778.5     32.7     30     44GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:MGI.::GO:0060712; P:spongiotrophoblast layer development; IMP:MGI.
372Q873X0    613   PACC_GIBMO pH-response transcription factor p...320.1     38.9     44     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
373Q8CJ78    1038   ZN628_MOUSE Zinc finger protein 628 OS=Mus mu...527.4     33.1     37     52GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
374B4NEU8    379   ATBP_DROWI AT-rich binding protein OS=Drosoph...800.11     38.5     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.
375O15209    634   ZBT22_HUMAN Zinc finger and BTB domain-contai...452.3     34.7     29     51GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
376Q92766    1687   RREB1_HUMAN Ras-responsive element-binding pr...630.25     37.7     32     52GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
377Q1H9T6    681   ZBT48_MOUSE Zinc finger and BTB domain-contai...558.1     32.7     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
378Q9BR84    538   ZN559_HUMAN Zinc finger protein 559 OS=Homo s...500.12     38.5     42     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
379Q9Y2D9    606   ZN652_HUMAN Zinc finger protein 652 OS=Homo s...476.5     33.1     28     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
380Q7Z340    670   ZN551_HUMAN Zinc finger protein 551 OS=Homo s...664.4     33.5     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
381Q03125    231   NRG1_YEAST Transcriptional regulator NRG1 OS=...550.13     37.7     36     51GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042710; P:biofilm formation; IMP:SGD.::GO:0071475; P:cellular hyperosmotic salinity response; IMP:SGD.::GO:0071469; P:cellular response to alkalinity; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IGI:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0097201; P:negative regulation of transcription from RNA polymerase II promoter in response to stress; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IGI:SGD.
382Q96X49    621   PACC_CEPAC pH-response transcription factor p...320.13     38.5     44     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
383Q8NCA9    323   ZN784_HUMAN Zinc finger protein 784 OS=Homo s...1310.13     38.1     25     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
384Q15929    161   ZNF56_HUMAN Putative zinc finger protein 56 O...650.13     37     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
385Q9P0T4    197   ZN581_HUMAN Zinc finger protein 581 OS=Homo s...518.3     32     37     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
386Q99612    283   KLF6_HUMAN Krueppel-like factor 6 OS=Homo sap...920.13     38.1     29     43GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
387P23607    742   ZFA_MOUSE Zinc finger autosomal protein OS=Mu...674.5     33.5     25     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
388Q921B4    824   NRIF2_MOUSE Neurotrophin receptor-interacting...490.13     38.5     37     59GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005166; F:neurotrophin p75 receptor binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
389P19544    449   WT1_HUMAN Wilms tumor protein OS=Homo sapiens...511.1     35.4     33     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0060923; P:cardiac muscle cell fate commitment; ISS:BHF-UCL.::GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; IDA:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IGI:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IGI:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; IDA:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; IGI:UniProtKB.
390B7ZSG3    414   WT1A_XENLA Wilms tumor protein homolog A OS=X...511     35.4     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; IMP:UniProtKB.::GO:1900207; P:negative regulation of pronephric nephron tubule development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0039004; P:specification of pronephric proximal tubule identity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
391Q5TJE2    640   ZBT22_CANFA Zinc finger and BTB domain-contai...730.14     38.5     36     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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