Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR070W
Length:
490
Number of sequences:
5887
Description:
YMR070W MOT3 SGDID:S000004674, Chr XIII from 409154-410626, Genome Release 64-1-1, Verified ORF, "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes; can form the [MOT3+] prion"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181A1C6L9    425   CREA_ASPCL Probable DNA-binding protein creA ...600.005     42.7     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
182Q8BLM0    355   KLF8_MOUSE Krueppel-like factor 8 OS=Mus musc...630.005     42.7     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
183Q60542    1043   ZEB1_MESAU Zinc finger E-box-binding homeobox...721.4     35.4     29     46GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
184P37275    1124   ZEB1_HUMAN Zinc finger E-box-binding homeobox...723.2     34.3     29     44GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
185Q62947    1109   ZEB1_RAT Zinc finger E-box-binding homeobox 1...721.7     35     29     46GO:0005634; C:nucleus; IDA:RGD.
GO:0003682; F:chromatin binding; IDA:RGD.::GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD.::GO:0043565; F:sequence-specific DNA binding; IMP:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:RGD.::GO:0008270; F:zinc ion binding; TAS:RGD.
GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:RGD.::GO:0030900; P:forebrain development; IEP:RGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
186P46974    1380   RSF2_YEAST Respiration factor 2 OS=Saccharomy...770.005     43.1     29     49GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
187Q5DWN0    422   GFI1_CANFA Zinc finger protein Gfi-1 OS=Canis...482.7     34.3     35     50GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
188Q80X44    710   ZBT24_MOUSE Zinc finger and BTB domain-contai...492.9     34.3     35     51GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
189Q9BXK1    252   KLF16_HUMAN Krueppel-like factor 16 OS=Homo s...510.078     38.5     39     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
190Q8IX07    1006   FOG1_HUMAN Zinc finger protein ZFPM1 OS=Homo ...560.006     43.1     43     57GO:0005667; C:transcription factor complex; IDA:BHF-UCL.::GO:0017053; C:transcriptional repressor complex; IDA:BHF-UCL.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.::GO:0003181; P:atrioventricular valve morphogenesis; ISS:BHF-UCL.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0055008; P:cardiac muscle tissue morphogenesis; ISS:BHF-UCL.::GO:0003192; P:mitral valve formation; ISS:BHF-UCL.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.::GO:0045403; P:negative regulation of interleukin-4 biosynthetic process; IDA:BHF-UCL.::GO:0060377; P:negative regulation of mast cell differentiation; ISS:BHF-UCL.::GO:0032091; P:negative regulation of protein binding; ISS:BHF-UCL.::GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.::GO:0030220; P:platelet formation; IGI:BHF-UCL.::GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:BHF-UCL.::GO:0010724; P:regulation of definitive erythrocyte differentiation; IDA:BHF-UCL.::GO:0002295; P:T-helper cell lineage commitment; IC:BHF-UCL.::GO:0071733; P:transcriptional activation by promoter-enhancer looping; ISS:BHF-UCL.::GO:0003195; P:tricuspid valve formation; ISS:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
191Q6DCW1    343   GFI1B_XENLA Zinc finger protein Gfi-1b OS=Xen...575.5     33.1     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
192P70338    423   GFI1_MOUSE Zinc finger protein Gfi-1 OS=Mus m...483     33.9     35     50GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042491; P:auditory receptor cell differentiation; IMP:MGI.::GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0007638; P:mechanosensory behavior; IMP:MGI.::GO:0009996; P:negative regulation of cell fate specification; IMP:MGI.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042660; P:positive regulation of cell fate specification; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
193Q07120    423   GFI1_RAT Zinc finger protein Gfi-1 OS=Rattus ...673.1     33.9     33     49GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
194Q91X45    518   ZBTB3_MOUSE Zinc finger and BTB domain-contai...1120.006     42.7     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
195Q99684    422   GFI1_HUMAN Zinc finger protein Gfi-1 OS=Homo ...483.7     33.9     35     50GO:0016604; C:nuclear body; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.::GO:0070105; P:positive regulation of interleukin-6-mediated signaling pathway; IDA:UniProtKB.::GO:0034121; P:regulation of toll-like receptor signaling pathway; IDA:UniProtKB.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; TAS:ProtInc.
196Q8CII0    484   ZBT8B_MOUSE Zinc finger and BTB domain-contai...480.007     42.7     40     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
197Q6PGE4    1016   ZF316_MOUSE Zinc finger protein 316 OS=Mus mu...526.5     33.1     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
198O94166    431   CREA_ASPAC DNA-binding protein creA OS=Asperg...520.007     42.4     29     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
199P08152    470   EGR2_MOUSE E3 SUMO-protein ligase EGR2 OS=Mus...1260.007     42.4     27     40GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035284; P:brain segmentation; IMP:MGI.::GO:0071310; P:cellular response to organic substance; IDA:MGI.::GO:0021612; P:facial nerve structural organization; IGI:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006611; P:protein export from nucleus; IDA:UniProtKB.::GO:0030278; P:regulation of ossification; IMP:MGI.::GO:0021660; P:rhombomere 3 formation; IMP:MGI.::GO:0021666; P:rhombomere 5 formation; IMP:MGI.::GO:0007622; P:rhythmic behavior; IDA:MGI.::GO:0014037; P:Schwann cell differentiation; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
200A2QCJ9    427   CREA_ASPNC Probable DNA-binding protein creA ...520.007     42.4     29     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
201Q642B2    468   ZN672_RAT Zinc finger protein 672 OS=Rattus n...1090.007     42.4     32     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
202Q9UIH9    416   KLF15_HUMAN Krueppel-like factor 15 OS=Homo s...451.1     35.4     38     53GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IC:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
203Q9P889    429   CREA_ASPOR DNA-binding protein creA OS=Asperg...520.007     42.4     29     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
204B8NGC8    429   CREA_ASPFN Probable DNA-binding protein creA ...520.007     42.4     29     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
205Q5RAU9    589   ZN131_PONAB Zinc finger protein 131 OS=Pongo ...510.007     42.4     41     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
206P11161    476   EGR2_HUMAN E3 SUMO-protein ligase EGR2 OS=Hom...1030.007     42.4     27     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
207Q05159    412   EGR2B_DANRE Early growth response protein 2b ...1030.007     42.4     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
208Q9EPW2    415   KLF15_MOUSE Krueppel-like factor 15 OS=Mus mu...450.93     35.8     38     53
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
209P51774    470   EGR2_RAT E3 SUMO-protein ligase EGR2 OS=Rattu...1030.008     42.4     27     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007611; P:learning or memory; IEP:RGD.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:RGD.
210Q12145    317   YP013_YEAST Zinc finger protein YPR013C OS=Sa...570.009     42     39     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
211Q09838    681   PRZ1_SCHPO Transcriptional regulator prz1 OS=...542.3     34.7     35     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019722; P:calcium-mediated signaling; IDA:PomBase.::GO:0006874; P:cellular calcium ion homeostasis; IDA:PomBase.
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