Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR070W
Length:
490
Number of sequences:
5887
Description:
YMR070W MOT3 SGDID:S000004674, Chr XIII from 409154-410626, Genome Release 64-1-1, Verified ORF, "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes; can form the [MOT3+] prion"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P54785    490   MOT3_YEAST Transcriptional activator/represso...4900     969     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071474; P:cellular hyperosmotic response; IMP:SGD.::GO:0010895; P:negative regulation of ergosterol biosynthetic process; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q9UM63    463   PLAL1_HUMAN Zinc finger protein PLAGL1 OS=Hom...840.00000001     60.8     35     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q2I689    463   PLAL1_PIG Zinc finger protein PLAGL1 OS=Sus s...820.00000001     60.5     34     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q5U2T6    499   PLAG1_RAT Zinc finger protein PLAG1 OS=Rattus...435.5     33.1     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q9QYE0    499   PLAG1_MOUSE Zinc finger protein PLAG1 OS=Mus ...435.6     33.1     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0022612; P:gland morphogenesis; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.::GO:0035265; P:organ growth; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IDA:UniProtKB.::GO:0060736; P:prostate gland growth; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6P33749    630   MSN4_YEAST Zinc finger protein MSN4 OS=Saccha...570.00000004     59.3     46     65GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; IGI:SGD.::GO:0061401; P:positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment; IGI:SGD.::GO:0061402; P:positive regulation of transcription from RNA polymerase II promoter in response to acidity; IMP:SGD.::GO:0061422; P:positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; IGI:SGD.::GO:0061412; P:positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; IGI:SGD.::GO:0061395; P:positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; IGI:SGD.::GO:0061410; P:positive regulation of transcription from RNA polymerase II promoter in response to ethanol; IGI:SGD.::GO:0061409; P:positive regulation of transcription from RNA polymerase II promoter in response to freezing; IGI:SGD.::GO:0061406; P:positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation; IGI:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0061407; P:positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide; IMP:SGD.::GO:0061405; P:positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure; IGI:SGD.::GO:0061404; P:positive regulation of transcription from RNA polymerase II promoter in response to increased salt; IGI:SGD.::GO:0061403; P:positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress; IGI:SGD.::GO:0097236; P:positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; IGI:SGD.::GO:0001302; P:replicative cell aging; IGI:SGD.
7Q58NQ5    501   PLAG1_CHICK Zinc finger protein PLAG1 OS=Gall...488.8     32.7     38     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q6DJT9    500   PLAG1_HUMAN Zinc finger protein PLAG1 OS=Homo...434.8     33.5     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9B4F6U4    1173   PRD10_XENTR PR domain zinc finger protein 10 ...490.45     37     37     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q3UTQ7    1184   PRD10_MOUSE PR domain zinc finger protein 10 ...550.79     36.2     38     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q9NQV6    1147   PRD10_HUMAN PR domain zinc finger protein 10 ...550.49     37     38     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q5RAX9    1117   PRD10_PONAB PR domain zinc finger protein 10 ...550.51     37     38     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13O70494    783   SP3_MOUSE Transcription factor Sp3 OS=Mus mus...560.006     43.1     38     50GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0030851; P:granulocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0030224; P:monocyte differentiation; IMP:MGI.::GO:0001779; P:natural killer cell differentiation; IMP:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
14Q90WR8    771   SP3_CHICK Transcription factor Sp3 OS=Gallus ...730.006     42.7     34     47GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15A2BID7    1121   PRD10_DANRE PR domain zinc finger protein 10 ...690.33     37.4     32     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P33748    704   MSN2_YEAST Zinc finger protein MSN2 OS=Saccha...480.000001     54.7     52     60GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071406; P:cellular response to methylmercury; IMP:SGD.::GO:0006338; P:chromatin remodeling; IGI:SGD.::GO:0061401; P:positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment; IGI:SGD.::GO:0061402; P:positive regulation of transcription from RNA polymerase II promoter in response to acidity; IMP:SGD.::GO:0061422; P:positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; IGI:SGD.::GO:0061412; P:positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; IGI:SGD.::GO:0061395; P:positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; IGI:SGD.::GO:0061410; P:positive regulation of transcription from RNA polymerase II promoter in response to ethanol; IGI:SGD.::GO:0061409; P:positive regulation of transcription from RNA polymerase II promoter in response to freezing; IGI:SGD.::GO:0061406; P:positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation; IGI:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0061407; P:positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide; IMP:SGD.::GO:0061405; P:positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure; IGI:SGD.::GO:0061404; P:positive regulation of transcription from RNA polymerase II promoter in response to increased salt; IGI:SGD.::GO:0061403; P:positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress; IGI:SGD.::GO:0097236; P:positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; IGI:SGD.::GO:0001302; P:replicative cell aging; IGI:SGD.
17Q9UPG8    496   PLAL2_HUMAN Zinc finger protein PLAGL2 OS=Hom...446     33.1     39     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q02447    781   SP3_HUMAN Transcription factor Sp3 OS=Homo sa...560.009     42.4     38     50GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
19O74252    692   STE12_EMENI Transcription factor steA OS=194 ...970.000004     53.1     30     51GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0019953; P:sexual reproduction; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q505G8    1078   ZN827_MOUSE Zinc finger protein 827 OS=Mus mu...1374.9     33.5     26     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q62445    782   SP4_MOUSE Transcription factor Sp4 OS=Mus mus...590.004     43.5     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008016; P:regulation of heart contraction; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q02446    784   SP4_HUMAN Transcription factor Sp4 OS=Homo sa...590.002     44.3     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q6BEB4    398   SP5_HUMAN Transcription factor Sp5 OS=Homo sa...530.74     35.8     36     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q9JHX2    398   SP5_MOUSE Transcription factor Sp5 OS=Mus mus...530.81     35.8     36     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060349; P:bone morphogenesis; IGI:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035121; P:tail morphogenesis; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q17R98    1081   ZN827_HUMAN Zinc finger protein 827 OS=Homo s...481.3     35.4     38     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q9BE73    1081   ZN827_MACFA Zinc finger protein 827 OS=Macaca...481.3     35.4     38     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q14119    521   VEZF1_HUMAN Vascular endothelial zinc finger ...494.9     33.5     37     45GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
28Q99KE8    643   ZFP64_MOUSE Zinc finger protein 64 OS=Mus mus...506.9     33.1     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q9NTW7    645   ZF64B_HUMAN Zinc finger protein 64 homolog, i...508.5     32.7     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q9Y7G2    574   MIG1_CANAX Regulatory protein MIG1 OS=Candida...560.00002     50.8     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31P60319    205   KEN_DROYA Probable transcription factor Ken O...1320.00002     48.9     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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