Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR015C
Length:
538
Number of sequences:
5887
Description:
YMR015C ERG5 SGDID:S000004617, Chr XIII from 302485-300869, Genome Release 64-1-1, reverse complement, Verified ORF, "C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P49602    561   CP51_USTMA Lanosterol 14-alpha demethylase OS...3682e-18     92.4     22     40GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
32Q9JMA7    504   CP341_MOUSE Cytochrome P450 3A41 OS=Mus muscu...2372e-18     91.7     30     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
33P24462    503   CP3A7_HUMAN Cytochrome P450 3A7 OS=Homo sapie...1923e-18     91.3     28     53GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
34P05183    504   CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve...3983e-18     91.3     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD.
GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD.
35Q9VL92    526   CP4E3_DROME Cytochrome P450 4e3 OS=Drosophila...1794e-18     91.3     30     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
36O88833    509   CP4AA_MOUSE Cytochrome P450 4A10 OS=Mus muscu...3935e-18     90.5     23     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB.
GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006631; P:fatty acid metabolic process; TAS:UniProtKB.
37Q949P1    467   ABAH1_ARATH Abscisic acid 8'-hydroxylase 1 OS...4765e-18     90.5     22     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0009687; P:abscisic acid metabolic process; IMP:TAIR.::GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0048838; P:release of seed from dormancy; IMP:TAIR.::GO:0009639; P:response to red or far red light; IEP:TAIR.
38Q9GJX5    504   CP4AL_PIG Taurochenodeoxycholic 6 alpha-hydro...4458e-18     90.1     22     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC.
39P51538    503   CP3A9_RAT Cytochrome P450 3A9 OS=Rattus norve...3858e-18     90.1     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; TAS:RGD.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
40Q9V3S0    556   CP4G1_DROME Cytochrome P450 4g1 OS=Drosophila...2111e-17     89.7     27     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IMP:FlyBase.
41P33268    503   CP3A8_MACFA Cytochrome P450 3A8 OS=Macaca fas...1871e-17     89.7     28     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
42O55127    497   CP26A_MOUSE Cytochrome P450 26A1 OS=Mus muscu...3831e-17     89.7     23     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0007417; P:central nervous system development; IMP:MGI.::GO:0014032; P:neural crest cell development; IGI:MGI.::GO:0048384; P:retinoic acid receptor signaling pathway; IGI:MGI.
43Q91WL5    508   CP4CA_MOUSE Cytochrome P450 4A12A OS=Mus musc...1841e-17     89.4     31     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.
GO:0018685; F:alkane 1-monooxygenase activity; IDA:MGI.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB.
44P51869    522   CP4F4_RAT Cytochrome P450 4F4 OS=Rattus norve...1942e-17     89.4     25     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:RGD.
45Q05JG2    471   ABAH1_ORYSJ Abscisic acid 8'-hydroxylase 1 OS...4482e-17     89     24     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
46Q09J79    471   ABAH1_ORYSI Abscisic acid 8'-hydroxylase 1 OS...4482e-17     89     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
47Q9W011    510   C4D20_DROME Probable cytochrome P450 4d20 OS=...1982e-17     89     28     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
48Q8SPK0    504   CP4AP_PIG Cytochrome P450 4A25 OS=Sus scrofa ...1822e-17     89     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
49Q8SPK1    504   CP4AO_PIG Cytochrome P450 4A24 OS=Sus scrofa ...1823e-17     88.6     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
50Q8N118    509   CP4X1_HUMAN Cytochrome P450 4X1 OS=Homo sapie...3873e-17     88.2     24     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
51Q6NT55    531   CP4FN_HUMAN Cytochrome P450 4F22 OS=Homo sapi...3633e-17     88.2     23     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
52O18993    503   CP3AL_CALJA Cytochrome P450 3A21 OS=Callithri...1924e-17     87.8     28     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
53P08516    509   CP4AA_RAT Cytochrome P450 4A10 OS=Rattus norv...3644e-17     87.8     23     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.
GO:0018685; F:alkane 1-monooxygenase activity; IMP:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IDA:RGD.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0019369; P:arachidonic acid metabolic process; IMP:RGD.::GO:0046456; P:icosanoid biosynthetic process; IMP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0043651; P:linoleic acid metabolic process; IDA:RGD.::GO:0001890; P:placenta development; IEP:RGD.
54O70537    501   CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice...3424e-17     87.8     25     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
55Q9EP75    524   CP4FE_MOUSE Leukotriene-B4 omega-hydroxylase ...1945e-17     87.4     25     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC.
56P33274    524   CP4F1_RAT Cytochrome P450 4F1 OS=Rattus norve...1955e-17     87.4     26     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.
GO:0050544; F:arachidonic acid binding; IDA:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IDA:RGD.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:RGD.
GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
57Q64406    503   CP3AF_CAVPO Cytochrome P450 3A15 OS=Cavia por...2685e-17     87.4     29     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
58P04800    504   CP3A1_RAT Cytochrome P450 3A1 OS=Rattus norve...3995e-17     87.4     25     42GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
59P14581    511   CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu...1946e-17     87.4     28     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
60Q9V6H1    518   CP9H1_DROME Probable cytochrome P450 9h1 OS=D...2066e-17     87.4     28     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
61Q64464    503   CP3AD_MOUSE Cytochrome P450 3A13 OS=Mus muscu...2389e-17     86.7     28     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0010628; P:positive regulation of gene expression; IMP:MGI.
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