Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML121W
Length:
310
Number of sequences:
5887
Description:
YML121W GTR1 SGDID:S000004590, Chr XIII from 26930-27862, Genome Release 64-1-1, Verified ORF, "Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P61021    215   RAB5B_MOUSE Ras-related protein Rab-5B OS=Mus...1300.15     36.6     25     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.
GO:0007032; P:endosome organization; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
92P61020    215   RAB5B_HUMAN Ras-related protein Rab-5B OS=Hom...1300.15     36.6     25     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
93Q68Y52    214   RAC2_ORYSJ Rac-like GTP-binding protein 2 OS=...1240.17     36.6     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
94Q181S7    459   MNME_CLOD6 tRNA modification GTPase MnmE OS=C...2040.19     37     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006400; P:tRNA modification; IEA:InterPro.
95Q5ZHW4    215   RAB5B_CHICK Ras-related protein Rab-5B OS=Gal...1300.19     36.2     25     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
96P46629    213   RAB25_RABIT Ras-related protein Rab-25 OS=Ory...1300.19     36.2     31     48GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031268; P:pseudopodium organization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
97Q899S2    459   MNME_CLOTE tRNA modification GTPase MnmE OS=C...1520.2     37     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
98Q17WL7    462   DER_HELAH GTPase Der OS=Helicobacter acinonyc...1580.2     37     23     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
99P39110    191   CIN4_YEAST GTP-binding protein CIN4 OS=Saccha...1330.22     36.2     27     51GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005525; F:GTP binding; ISS:SGD.
GO:0006457; P:protein folding; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
100P34143    196   RABC_DICDI Ras-related protein RabC OS=Dictyo...1270.22     36.2     28     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
101Q5QZJ5    458   MNME_IDILO tRNA modification GTPase MnmE OS=I...1270.23     36.6     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
102Q38912    198   RAC3_ARATH Rac-like GTP-binding protein ARAC3...1310.23     35.8     24     47GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030427; C:site of polarized growth; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
103Q58DW6    213   RAB25_BOVIN Ras-related protein Rab-25 OS=Bos...1300.24     36.2     31     48GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0031260; C:pseudopodium membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031268; P:pseudopodium organization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
104Q40194    218   RB11D_LOTJA Ras-related protein Rab11D OS=Lot...2160.25     36.2     25     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
105Q8VEA8    199   RAB7B_MOUSE Ras-related protein Rab-7b OS=Mus...1430.25     35.8     33     45GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; IMP:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
106P06781    192   RHO2_YEAST GTP-binding protein RHO2 OS=Saccha...1400.25     35.8     24     41GO:0005622; C:intracellular; TAS:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0007015; P:actin filament organization; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.::GO:0007017; P:microtubule-based process; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
107O82480    209   RAC7_ARATH Rac-like GTP-binding protein ARAC7...1310.26     35.8     23     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
108P51158    221   RAB28_RAT Ras-related protein Rab-28 OS=Rattu...1320.26     35.8     23     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:RGD.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
109P38542    215   RAN_BRUMA GTP-binding nuclear protein Ran OS=...980.26     35.8     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
110P57735    213   RAB25_HUMAN Ras-related protein Rab-25 OS=Hom...1300.27     35.8     31     48GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0031260; C:pseudopodium membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031268; P:pseudopodium organization; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
111Q99KL7    221   RAB28_MOUSE Ras-related protein Rab-28 OS=Mus...1320.29     35.8     23     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
112Q5S006    2527   LRRK2_MOUSE Leucine-rich repeat serine/threon...1600.29     36.6     19     45GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0005802; C:trans-Golgi network; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.
GO:0010508; P:positive regulation of autophagy; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0035564; P:regulation of kidney size; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
113Q5S007    2527   LRRK2_HUMAN Leucine-rich repeat serine/threon...1600.29     36.6     19     46GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL.
GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL.
114O23657    212   RABC1_ARATH Ras-related protein RABC1 OS=Arab...1070.3     35.8     31     50GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
115Q9WTL2    213   RAB25_MOUSE Ras-related protein Rab-25 OS=Mus...1300.31     35.8     31     48GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0031260; C:pseudopodium membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031268; P:pseudopodium organization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
116A8AXP0    457   MNME_STRGC tRNA modification GTPase MnmE OS=V...1310.32     36.2     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
117Q9P8J9    206   RHO3_SCHCO GTP-binding protein Rho3 OS=Schizo...1270.32     35.8     24     52GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
118Q5FVJ7    185   RABL5_RAT Rab-like protein 5 OS=Rattus norveg...1260.32     35.4     22     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
119Q54HK2    190   ARFF_DICDI ADP-ribosylation factor F OS=Dicty...1330.33     35.4     25     46GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
120Q627K4    184   ARL2_CAEBR ADP-ribosylation factor-like prote...1260.34     35.4     28     43GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030540; P:female genitalia development; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
121Q7RVL0    215   GSP1_NEUCR GTP-binding nuclear protein GSP1/R...1080.34     35.4     26     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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