UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YML102W

Length:

468

Number of sequences:

5887

Description:

YML102W CAC2 SGDID:S000004570, Chr XIII from 68294-69700, Genome Release 64-1-1, Verified ORF, "Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	C3XVT5	406	LIS1_BRAFL Lissencephaly-1 homolog OS=Branchi...	149	2.8	33.9	20	40	GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
62	Q2HJH6	358	SNR40_BOVIN U5 small nuclear ribonucleoprotei...	204	0.000005	52	22	41	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
63	O74309	807	SLM9_SCHPO Histone transcription regulator sl...	229	0.000006	52.4	27	41	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000417; C:HIR complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; TAS:PomBase.
									GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64	A8IZG4	352	CIAO1_CHLRE Probable cytosolic iron-sulfur pr...	164	0.038	40	23	41
65	B4KTK4	331	CIAO1_DROMO Probable cytosolic iron-sulfur pr...	92	3.4	33.5	27	51
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
66	Q9QXE7	527	TBL1X_MOUSE F-box-like/WD repeat-containing p...	114	1.3	35	29	44	GO:0005667; C:transcription factor complex; IDA:MGI.
									GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
									GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0043627; P:response to estrogen stimulus; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67	Q5ZJH5	305	WDR61_CHICK WD repeat-containing protein 61 O...	53	3.1	33.9	38	55	GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
									GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
68	Q8VEJ4	485	NLE1_MOUSE Notchless protein homolog 1 OS=Mus...	202	0.021	40.8	24	38	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0001826; P:inner cell mass cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.
69	B0XAF3	338	CIAO1_CULQU Probable cytosolic iron-sulfur pr...	91	1.8	34.7	29	48
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
70	Q5RF51	357	SNR40_PONAB U5 small nuclear ribonucleoprotei...	204	0.000009	51.2	21	42	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
71	Q58D20	485	NLE1_BOVIN Notchless protein homolog 1 OS=Bos...	71	0.008	42.4	34	54	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
72	B4P7Q3	335	CIAO1_DROYA Probable cytosolic iron-sulfur pr...	153	0.6	36.2	20	41
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
73	Q5DFU0	352	CIAO1_SCHJA Probable cytosolic iron-sulfur pr...	168	0.025	40.4	23	40
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
74	Q5RE95	330	WDR5B_PONAB WD repeat-containing protein 5B O...	151	0.00001	50.8	23	46
75	Q55563	1693	Y163_SYNY3 Uncharacterized WD repeat-containi...	198	0.19	38.1	23	37
									GO:0005488; F:binding; IEA:InterPro.
76	Q5M786	334	WDR5_XENTR WD repeat-containing protein 5 OS=...	151	0.00001	50.8	23	43	GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77	Q2KIG2	334	WDR5_BOVIN WD repeat-containing protein 5 OS=...	176	8.6	32.3	20	38	GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78	Q9NVX2	485	NLE1_HUMAN Notchless protein homolog 1 OS=Hom...	71	0.017	41.2	32	54	GO:0005730; C:nucleolus; IDA:HPA.
79	Q498M4	334	WDR5_RAT WD repeat-containing protein 5 OS=Ra...	176	9	32.3	20	38	GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80	P61965	334	WDR5_MOUSE WD repeat-containing protein 5 OS=...	176	9	32.3	20	38	GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81	P61964	334	WDR5_HUMAN WD repeat-containing protein 5 OS=...	176	9	32.3	20	38	GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82	Q6PE01	358	SNR40_MOUSE U5 small nuclear ribonucleoprotei...	204	0.00001	50.4	21	41
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
83	Q5RFF8	485	NLE1_PONAB Notchless protein homolog 1 OS=Pon...	71	0.017	41.2	32	54	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
84	B7QKS1	315	CIAO1_IXOSC Probable cytosolic iron-sulfur pr...	209	1.8	34.7	22	37
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
85	O74855	502	NLE1_SCHPO Ribosome assembly protein C18.05c ...	78	0.92	35.8	27	45	GO:0005730; C:nucleolus; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0042254; P:ribosome biogenesis; ISS:PomBase.
86	B3MC74	335	CIAO1_DROAN Probable cytosolic iron-sulfur pr...	158	0.11	38.5	22	39
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
87	Q8YRI1	1526	YY46_NOSS1 Uncharacterized WD repeat-containi...	147	2.6	34.3	20	41
88	B3NQR5	335	CIAO1_DROER Probable cytosolic iron-sulfur pr...	153	0.46	36.2	20	41
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
89	Q00808	1356	HETE1_PODAS Vegetative incompatibility protei...	150	1.8	35	21	41
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
90	Q99KN2	339	CIAO1_MOUSE Probable cytosolic iron-sulfur pr...	75	2.2	34.3	29	47	GO:0071817; C:MMXD complex; ISS:UniProtKB.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI.
									GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:MGI.
91	P93107	606	PF20_CHLRE Flagellar WD repeat-containing pro...	201	0.00003	50.1	24	41	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.

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