Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML097C
Length:
451
Number of sequences:
5887
Description:
YML097C VPS9 SGDID:S000004563, Chr XIII from 79690-78335, Genome Release 64-1-1, reverse complement, Verified ORF, "A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P54787    451   VPS9_YEAST Vacuolar protein sorting-associate...4510     917     100     100GO:0005829; C:cytosol; IDA:SGD.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
2O74396    572   VPS91_SCHPO Vacuolar protein sorting-associat...490.44     36.6     31     61GO:0005829; C:cytosol; ISS:PomBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.
GO:0006623; P:protein targeting to vacuole; ISS:PomBase.
3Q9LT31    520   VPS9A_ARATH Vacuolar protein sorting-associat...2631e-31     130     32     53GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:TAIR.
GO:0000919; P:cell plate assembly; IMP:TAIR.::GO:0042546; P:cell wall biogenesis; IMP:TAIR.::GO:0009790; P:embryo development; IMP:TAIR.::GO:0048528; P:post-embryonic root development; IMP:TAIR.
4Q9JM13    491   RABX5_MOUSE Rab5 GDP/GTP exchange factor OS=M...2832e-24     108     30     48GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
5O18973    492   RABX5_BOVIN Rab5 GDP/GTP exchange factor OS=B...2606e-24     107     30     50GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
6Q9UJ41    708   RABX5_HUMAN Rab5 GDP/GTP exchange factor OS=H...1854e-23     105     36     54GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
7A2RV61    1452   GAPD1_XENLA GTPase-activating protein and VPS...2070.000000000000005     81.6     27     49GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
8Q14C86    1478   GAPD1_HUMAN GTPase-activating protein and VPS...2320.00000000000003     79     25     48GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
9A5D794    1413   GAPD1_BOVIN GTPase-activating protein and VPS...2380.00000000000004     79     25     47GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
10Q6PAR5    1458   GAPD1_MOUSE GTPase-activating protein and VPS...2320.00000000000006     78.2     25     48GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
11O94388    402   VPS92_SCHPO Vacuolar protein sorting-associat...1820.00000000007     67.4     28     48GO:0005829; C:cytosol; IDA:PomBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.
GO:0006623; P:protein targeting to vacuole; ISS:PomBase.
12Q9VZ08    1712   RME6_DROME Receptor-mediated endocytosis prot...980.000000001     64.3     32     54GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
13Q8WYP3    895   RIN2_HUMAN Ras and Rab interactor 2 OS=Homo s...1920.000000008     61.6     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
14Q9D684    903   RIN2_MOUSE Ras and Rab interactor 2 OS=Mus mu...1140.00000001     61.2     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
15Q8C190    649   CP007_MOUSE Uncharacterized protein C16orf7 h...1520.00000001     61.2     26     48
16Q9GYH7    1093   RME6_CAEEL Receptor-mediated endocytosis prot...2130.00000002     60.8     23     45GO:0045334; C:clathrin-coated endocytic vesicle; IDA:WormBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.
GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:WormBase.
GO:0006897; P:endocytosis; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IGI:WormBase.::GO:0032851; P:positive regulation of Rab GTPase activity; IGI:WormBase.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IMP:WormBase.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
17Q29HW3    1774   RME6_DROPS Receptor-mediated endocytosis prot...1850.00000008     58.5     26     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
18A8WVM4    1104   RME6_CAEBR Receptor-mediated endocytosis prot...2410.0000002     57.4     23     43GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
19P59729    980   RIN3_MOUSE Ras and Rab interactor 3 OS=Mus mu...1160.00001     51.6     26     51GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
20Q8TB24    985   RIN3_HUMAN Ras and Rab interactor 3 OS=Homo s...1150.0001     48.5     26     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; NAS:UniProtKB.
GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
21Q9Y2B5    631   CP007_HUMAN Uncharacterized protein C16orf7 O...1420.0002     47.4     25     46GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; TAS:ProtInc.
GO:0015986; P:ATP synthesis coupled proton transport; TAS:ProtInc.
22Q6ZS11    452   RINL_HUMAN Ras and Rab interactor-like protei...1370.002     43.9     24     44
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
23Q96NW4    1050   ANR27_HUMAN Ankyrin repeat domain-containing ...960.002     44.3     31     58GO:0005769; C:early endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:LIFEdb.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0045022; P:early endosome to late endosome transport; IDA:MGI.
24Q921Q7    763   RIN1_MOUSE Ras and Rab interactor 1 OS=Mus mu...840.002     43.9     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
25P97680    774   RIN1_RAT Ras and Rab interactor 1 OS=Rattus n...840.002     43.9     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
26Q3UMR0    1048   ANR27_MOUSE Ankyrin repeat domain-containing ...960.003     43.5     30     60
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
27Q5REW9    1050   ANR27_PONAB Ankyrin repeat domain-containing ...960.004     43.1     31     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
28Q13671    783   RIN1_HUMAN Ras and Rab interactor 1 OS=Homo s...800.024     40.8     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
29Q8MQW8    1790   SPRI_DROME Protein sprint OS=Drosophila melan...980.035     40.4     26     46
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007298; P:border follicle cell migration; IGI:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
30Q80UW3    563   RINL_MOUSE Ras and Rab interactor-like protei...980.051     39.7     30     47GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006897; P:endocytosis; IDA:MGI.
31P57993    763   PKNG_MYCLE Probable serine/threonine-protein ...1350.075     39.3     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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