Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML082W
Length:
649
Number of sequences:
5887
Description:
YML082W YML082W SGDID:S000004547, Chr XIII from 101862-103811, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein predicted to have carbon-sulfur lyase activity; transcriptionally regulated by Upc2p via an upstream sterol response element; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and the cytoplasm; YML082W is not an essential gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q04533    649   METX_YEAST Putative cystathionine gamma-synth...6490     1350     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
2P47164    639   MET7_YEAST Cystathionine gamma-synthase OS=Sa...6630     708     55     70GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003962; F:cystathionine gamma-synthase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0019346; P:transsulfuration; IMP:SGD.
3O74314    610   MET7_SCHPO Probable cystathionine gamma-synth...6671e-116     368     36     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0003962; F:cystathionine gamma-synthase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006534; P:cysteine metabolic process; ISS:PomBase.::GO:0019281; P:L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine; ISS:PomBase.
4P38675    621   MET7_NEUCR Cystathionine gamma-synthase OS=12...6673e-113     359     36     51
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
5Q12198    575   METW_YEAST Putative cystathionine gamma-synth...2001e-22     105     34     50
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
6P56069    380   METB_HELPY Cystathionine gamma-synthase OS=py...3493e-16     84.3     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
7Q1M0P5    380   METB_HELPX Cystathionine gamma-synthase OS=He...3439e-16     83.2     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
8Q9ZMW7    380   METB_HELPJ Cystathionine gamma-synthase OS=He...3430.000000000000004     81.3     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
9A2RM21    380   METC_LACLM Cystathionine beta-lyase OS=Lactoc...2660.00000000000005     77.8     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
10P0A4K2    380   METC_LACLA Cystathionine beta-lyase OS=lactis...2660.00000000000005     77.8     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
11O05394    379   MCCB_BACSU Cystathionine gamma-lyase OS=Bacil...3290.00000000000005     77.8     26     43
GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0047982; F:homocysteine desulfhydrase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
12P0C2T9    380   METC_LACLC Cystathionine beta-lyase OS=Lactoc...2620.0000000000001     76.3     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
13O31632    390   METC_BACSU Cystathionine beta-lyase metC OS=B...3480.000000000001     73.6     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
14P38716    378   YHR2_YEAST Uncharacterized trans-sulfuration ...3020.00000001     61.2     24     43GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
15P55217    563   METB_ARATH Cystathionine gamma-synthase, chlo...2400.00000002     61.2     26     45GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0003962; F:cystathionine gamma-synthase activity; IDA:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IMP:TAIR.::GO:0001887; P:selenium compound metabolic process; IDA:TAIR.
16P00935    386   METB_ECOLI Cystathionine gamma-synthase OS=Es...2650.00000004     59.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IDA:EcoCyc.::GO:0042802; F:identical protein binding; IPI:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc.
GO:0009086; P:methionine biosynthetic process; IMP:EcoCyc.
17P24601    319   METB_HERAU Probable cystathionine gamma-synth...3000.00000009     57.8     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
18Q8VCN5    398   CGL_MOUSE Cystathionine gamma-lyase OS=Mus mu...2640.0000002     57.4     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0044524; P:protein sulfhydration; IDA:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
19P13254    398   MEGL_PSEPU Methionine gamma-lyase OS=Pseudomo...3040.0000003     56.6     24     44
GO:0018826; F:methionine gamma-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
20P44502    369   METB_HAEIN Cystathionine gamma-synthase OS=Ha...2450.0000009     55.1     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
21Q19QT7    405   CGL_PIG Cystathionine gamma-lyase OS=Sus scro...2540.0000009     55.1     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
22Q55DV9    387   CGL_DICDI Cystathionine gamma-lyase OS=Dictyo...2580.000001     55.1     26     45GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.
GO:0004123; F:cystathionine gamma-lyase activity; ISS:dictyBase.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
23P46807    388   METB_MYCLE Cystathionine gamma-synthase OS=My...2410.000001     54.7     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
24O31631    373   METI_BACSU Cystathionine gamma-synthase/O-ace...2550.000003     53.5     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
25Q83A83    387   METC_COXBU Cystathionine beta-lyase OS=Coxiel...3480.000004     53.1     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
26P66875    388   METB_MYCTU Cystathionine gamma-synthase OS=My...2560.000006     52.4     26     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004123; F:cystathionine gamma-lyase activity; IDA:MTBBASE.::GO:0003962; F:cystathionine gamma-synthase activity; IDA:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:MTBBASE.::GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IMP:MTBBASE.
27P66876    388   METB_MYCBO Cystathionine gamma-synthase OS=My...2560.000006     52.4     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
28P55216    392   CGL2_CAEEL Putative cystathionine gamma-lyase...2440.00001     52     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
29P95199    406   METZ_MYCTU O-succinylhomoserine sulfhydrylase...1620.00007     49.3     28     43
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0071268; P:homocysteine biosynthetic process; IEA:InterPro.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
30P18757    398   CGL_RAT Cystathionine gamma-lyase OS=Rattus n...2720.0001     48.9     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004121; F:cystathionine beta-lyase activity; IDA:RGD.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; IMP:RGD.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.::GO:0019346; P:transsulfuration; TAS:RGD.
31P31373    394   CYS3_YEAST Cystathionine gamma-lyase OS=Sacch...2600.0001     48.9     27     46GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004123; F:cystathionine gamma-lyase activity; IDA:SGD.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:SGD.::GO:0019346; P:transsulfuration; IMP:SGD.
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