rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | O89000 | 1025 | DPYD_RAT Dihydropyrimidine dehydrogenase [NAD... | 95 | 0.015 | 41.6 | 25 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0002058; F:uracil binding; IDA:RGD. | | | | | | | | | | GO:0007623; P:circadian rhythm; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IDA:RGD.::GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 152 | O27281 | 303 | PYRDB_METTH Dihydroorotate dehydrogenase B (N... | 74 | 0.017 | 40.4 | 26 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 153 | Q8CHR6 | 1025 | DPYD_MOUSE Dihydropyrimidine dehydrogenase [N... | 99 | 0.043 | 40 | 25 | 47 | GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 154 | Q5JHR7 | 302 | PYRDB_PYRKO Dihydroorotate dehydrogenase B (N... | 91 | 0.044 | 39.3 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 155 | Q5R895 | 1025 | DPYD_PONAB Dihydropyrimidine dehydrogenase [N... | 104 | 0.045 | 40 | 26 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 156 | Q12882 | 1025 | DPYD_HUMAN Dihydropyrimidine dehydrogenase [N... | 104 | 0.045 | 40 | 26 | 49 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006145; P:purine base catabolic process; IMP:UniProtKB.::GO:0006214; P:thymidine catabolic process; IDA:UniProtKB.::GO:0006210; P:thymine catabolic process; IDA:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; IDA:UniProtKB. | 157 | Q28007 | 1025 | DPYD_BOVIN Dihydropyrimidine dehydrogenase [N... | 95 | 0.076 | 39.3 | 24 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 158 | Q07PW9 | 260 | THIG_RHOP5 Thiazole synthase OS=Rhodopseudomo... | 83 | 0.083 | 38.1 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 159 | Q28943 | 1025 | DPYD_PIG Dihydropyrimidine dehydrogenase [NAD... | 95 | 0.12 | 38.5 | 24 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 160 | Q6NYG8 | 1022 | DPYD_DANRE Dihydropyrimidine dehydrogenase [N... | 99 | 0.13 | 38.5 | 25 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 161 | P20932 | 393 | MDLB_PSEPU (S)-mandelate dehydrogenase OS=Pse... | 107 | 0.2 | 37.4 | 28 | 47 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033720; F:(S)-mandelate dehydrogenase activity; IEA:EC.::GO:0010181; F:FMN binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0018924; P:mandelate metabolic process; IEA:UniProtKB-KW. | 162 | Q9YFI6 | 306 | PYRDA_AERPE Putative dihydroorotate dehydroge... | 112 | 0.23 | 37 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052888; F:dihydroorotate oxidase (fumarate) activity; IEA:EC.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 163 | Q8U0P6 | 300 | PYRDB_PYRFU Dihydroorotate dehydrogenase B (N... | 78 | 0.31 | 36.6 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 164 | Q89FP2 | 260 | THIG_BRAJA Thiazole synthase OS=Bradyrhizobiu... | 83 | 0.46 | 35.8 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 165 | Q55FT1 | 1009 | DPYD_DICDI Dihydropyrimidine dehydrogenase [N... | 124 | 0.47 | 36.6 | 26 | 43 | GO:0005829; C:cytosol; ISS:dictyBase. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 166 | Q133T5 | 260 | THIG_RHOPS Thiazole synthase OS=Rhodopseudomo... | 83 | 0.6 | 35.4 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 167 | B9J4E0 | 544 | SYM_BACCQ Methionine--tRNA ligase OS=Bacillus... | 68 | 0.73 | 35.8 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 168 | Q6N3W7 | 260 | THIG_RHOPA Thiazole synthase OS=Rhodopseudomo... | 83 | 0.75 | 35.4 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 169 | B3QFS7 | 260 | THIG_RHOPT Thiazole synthase OS=Rhodopseudomo... | 83 | 0.79 | 35.4 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 170 | B7HVW2 | 544 | SYM_BACC7 Methionine--tRNA ligase OS=Bacillus... | 68 | 1.1 | 35.4 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 171 | Q9CHU6 | 472 | 6PGD_LACLA 6-phosphogluconate dehydrogenase, ... | 172 | 1.3 | 35 | 22 | 41 | | | | | | | | | | | GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:EC. | | | | | | | | | | GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.::GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-KW. | 172 | B7INU9 | 544 | SYM_BACC2 Methionine--tRNA ligase OS=Bacillus... | 75 | 1.3 | 35 | 33 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 173 | Q89AX5 | 468 | 6PGD_BUCBP 6-phosphogluconate dehydrogenase, ... | 85 | 1.4 | 35 | 31 | 44 | | | | | | | | | | | GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; ISS:UniProtKB. | | | | | | | | | | GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.::GO:0006098; P:pentose-phosphate shunt; ISS:UniProtKB. | 174 | C3LD96 | 544 | SYM_BACAC Methionine--tRNA ligase OS=Bacillus... | 68 | 1.5 | 34.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 175 | C3P025 | 544 | SYM_BACAA Methionine--tRNA ligase OS=Bacillus... | 68 | 1.5 | 34.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 176 | Q81XF9 | 544 | SYM2_BACAN Methionine--tRNA ligase 2 OS=Bacil... | 68 | 1.5 | 34.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 177 | Q6HBM0 | 544 | SYM1_BACHK Methionine--tRNA ligase 1 OS=Bacil... | 68 | 1.6 | 34.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 178 | B7JEJ3 | 544 | SYM_BACC0 Methionine--tRNA ligase OS=Bacillus... | 68 | 1.6 | 34.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 179 | A5EPQ3 | 260 | THIG_BRASB Thiazole synthase OS=Bradyrhizobiu... | 83 | 1.7 | 34.3 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 180 | Q8CQV7 | 295 | PDXS_STAES Pyridoxal biosynthesis lyase PdxS ... | 48 | 1.8 | 34.3 | 38 | 54 | | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:InterPro. | 181 | Q5HRN5 | 295 | PDXS_STAEQ Pyridoxal biosynthesis lyase PdxS ... | 48 | 1.8 | 34.3 | 38 | 54 | | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:InterPro. |