Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML080W
Length:
423
Number of sequences:
5887
Description:
YML080W DUS1 SGDID:S000004545, Chr XIII from 108806-110077, Genome Release 64-1-1, Verified ORF, "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151O89000    1025   DPYD_RAT Dihydropyrimidine dehydrogenase [NAD...950.015     41.6     25     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0002058; F:uracil binding; IDA:RGD.
GO:0007623; P:circadian rhythm; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IDA:RGD.::GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
152O27281    303   PYRDB_METTH Dihydroorotate dehydrogenase B (N...740.017     40.4     26     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
153Q8CHR6    1025   DPYD_MOUSE Dihydropyrimidine dehydrogenase [N...990.043     40     25     47GO:0005829; C:cytosol; IDA:MGI.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
154Q5JHR7    302   PYRDB_PYRKO Dihydroorotate dehydrogenase B (N...910.044     39.3     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
155Q5R895    1025   DPYD_PONAB Dihydropyrimidine dehydrogenase [N...1040.045     40     26     49GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
156Q12882    1025   DPYD_HUMAN Dihydropyrimidine dehydrogenase [N...1040.045     40     26     49GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006145; P:purine base catabolic process; IMP:UniProtKB.::GO:0006214; P:thymidine catabolic process; IDA:UniProtKB.::GO:0006210; P:thymine catabolic process; IDA:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; IDA:UniProtKB.
157Q28007    1025   DPYD_BOVIN Dihydropyrimidine dehydrogenase [N...950.076     39.3     24     48GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
158Q07PW9    260   THIG_RHOP5 Thiazole synthase OS=Rhodopseudomo...830.083     38.1     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
159Q28943    1025   DPYD_PIG Dihydropyrimidine dehydrogenase [NAD...950.12     38.5     24     48GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
160Q6NYG8    1022   DPYD_DANRE Dihydropyrimidine dehydrogenase [N...990.13     38.5     25     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
161P20932    393   MDLB_PSEPU (S)-mandelate dehydrogenase OS=Pse...1070.2     37.4     28     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0033720; F:(S)-mandelate dehydrogenase activity; IEA:EC.::GO:0010181; F:FMN binding; IEA:InterPro.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0018924; P:mandelate metabolic process; IEA:UniProtKB-KW.
162Q9YFI6    306   PYRDA_AERPE Putative dihydroorotate dehydroge...1120.23     37     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0052888; F:dihydroorotate oxidase (fumarate) activity; IEA:EC.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
163Q8U0P6    300   PYRDB_PYRFU Dihydroorotate dehydrogenase B (N...780.31     36.6     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
164Q89FP2    260   THIG_BRAJA Thiazole synthase OS=Bradyrhizobiu...830.46     35.8     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
165Q55FT1    1009   DPYD_DICDI Dihydropyrimidine dehydrogenase [N...1240.47     36.6     26     43GO:0005829; C:cytosol; ISS:dictyBase.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
166Q133T5    260   THIG_RHOPS Thiazole synthase OS=Rhodopseudomo...830.6     35.4     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
167B9J4E0    544   SYM_BACCQ Methionine--tRNA ligase OS=Bacillus...680.73     35.8     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
168Q6N3W7    260   THIG_RHOPA Thiazole synthase OS=Rhodopseudomo...830.75     35.4     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
169B3QFS7    260   THIG_RHOPT Thiazole synthase OS=Rhodopseudomo...830.79     35.4     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
170B7HVW2    544   SYM_BACC7 Methionine--tRNA ligase OS=Bacillus...681.1     35.4     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
171Q9CHU6    472   6PGD_LACLA 6-phosphogluconate dehydrogenase, ...1721.3     35     22     41
GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.::GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-KW.
172B7INU9    544   SYM_BACC2 Methionine--tRNA ligase OS=Bacillus...751.3     35     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
173Q89AX5    468   6PGD_BUCBP 6-phosphogluconate dehydrogenase, ...851.4     35     31     44
GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; ISS:UniProtKB.
GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.::GO:0006098; P:pentose-phosphate shunt; ISS:UniProtKB.
174C3LD96    544   SYM_BACAC Methionine--tRNA ligase OS=Bacillus...681.5     34.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
175C3P025    544   SYM_BACAA Methionine--tRNA ligase OS=Bacillus...681.5     34.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
176Q81XF9    544   SYM2_BACAN Methionine--tRNA ligase 2 OS=Bacil...681.5     34.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
177Q6HBM0    544   SYM1_BACHK Methionine--tRNA ligase 1 OS=Bacil...681.6     34.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
178B7JEJ3    544   SYM_BACC0 Methionine--tRNA ligase OS=Bacillus...681.6     34.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
179A5EPQ3    260   THIG_BRASB Thiazole synthase OS=Bradyrhizobiu...831.7     34.3     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
180Q8CQV7    295   PDXS_STAES Pyridoxal biosynthesis lyase PdxS ...481.8     34.3     38     54
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:InterPro.
181Q5HRN5    295   PDXS_STAEQ Pyridoxal biosynthesis lyase PdxS ...481.8     34.3     38     54
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:InterPro.
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