Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML072C
Length:
1545
Number of sequences:
5887
Description:
YML072C TCB3 SGDID:S000004537, Chr XIII from 129367-124730, Genome Release 64-1-1, reverse complement, Verified ORF, "Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9QYX7    5038   PCLO_MOUSE Protein piccolo OS=Mus musculus (M...1180.00003     53.1     31     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; IDA:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB.
62P29101    422   SYT2_RAT Synaptotagmin-2 OS=Rattus norvegicus...970.0008     47.4     34     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD.
GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.
63P46935    887   NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4...1630.006     45.1     27     41GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI.
GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB.
64Q8N9I0    419   SYT2_HUMAN Synaptotagmin-2 OS=Homo sapiens (H...970.0009     47.4     34     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
65Q62746    511   SYT6_RAT Synaptotagmin-6 OS=Rattus norvegicus...932.9     36.2     27     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0000300; C:peripheral to membrane of membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.
66P47709    684   RP3A_RAT Rabphilin-3A OS=Rattus norvegicus (R...960.00009     50.8     35     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:RGD.::GO:0019898; C:extrinsic to membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008430; F:selenium binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0007420; P:brain development; IEP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
67P47708    681   RP3A_MOUSE Rabphilin-3A OS=Mus musculus (Mous...960.0001     50.4     35     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
68Q9VVI3    1007   NEDD4_DROME E3 ubiquitin-protein ligase Nedd-...960.32     39.3     29     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB.
69Q5T7P8    510   SYT6_HUMAN Synaptotagmin-6 OS=Homo sapiens (H...933.3     35.8     27     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0097038; C:perinuclear endoplasmic reticulum; ISS:BHF-UCL.::GO:0000300; C:peripheral to membrane of membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0060478; P:acrosomal vesicle exocytosis; IMP:BHF-UCL.
70Q0JHU5    159   ERG1_ORYSJ Elicitor-responsive protein 1 OS=O...980.18     38.1     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
71A2WWV5    159   ERG1_ORYSI Elicitor-responsive protein 1 OS=O...980.18     38.1     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
72Q9FVJ3    337   AGD12_ARATH ADP-ribosylation factor GTPase-ac...1250.0006     47.8     30     50GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0005543; F:phospholipid binding; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; TAS:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
73P41885    1106   RBF1_CAEEL Rabphilin-1 OS=Caenorhabditis eleg...1960.16     40.4     25     40GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IDA:WormBase.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.
74Q9ZVT9    1020   C2GR1_ARATH C2 and GRAM domain-containing pro...900.16     40.4     29     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
75Q9R0N9    491   SYT9_MOUSE Synaptotagmin-9 OS=Mus musculus (M...930.008     44.3     30     55GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
76Q925C0    491   SYT9_RAT Synaptotagmin-9 OS=Rattus norvegicus...930.009     44.3     30     55GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030667; C:secretory granule membrane; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:RGD.::GO:0050796; P:regulation of insulin secretion; IMP:RGD.
77Q06846    704   RP3A_BOVIN Rabphilin-3A OS=Bos taurus (Bovine...1490.0005     48.5     26     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
78Q9Y2J0    694   RP3A_HUMAN Rabphilin-3A OS=Homo sapiens (Huma...1490.0006     48.1     26     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
79Q96PU5    975   NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4...914.6     35.4     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB.
80Q9R0N8    511   SYT6_MOUSE Synaptotagmin-6 OS=Mus musculus (M...933.3     35.8     27     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:BHF-UCL.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:BHF-UCL.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007340; P:acrosome reaction; IDA:HGNC.
81Q8CFI0    1004   NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4...914.6     35.4     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
82Q5RBF2    959   NED4L_PONAB E3 ubiquitin-protein ligase NEDD4...914.7     35.4     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
83Q86SS6    491   SYT9_HUMAN Synaptotagmin-9 OS=Homo sapiens (H...930.011     43.9     30     55GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
84Q25378    658   KPC1_LYTPI Protein kinase C OS=Lytechinus pic...1020.0004     48.5     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
85P63319    697   KPCG_RAT Protein kinase C gamma type OS=Rattu...1230.0004     48.5     29     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0007611; P:learning or memory; IEP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:RGD.
86P63318    697   KPCG_MOUSE Protein kinase C gamma type OS=Mus...1230.0004     48.5     29     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0097060; C:synaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007635; P:chemosensory behavior; IMP:MGI.::GO:0060384; P:innervation; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; IMP:UniProtKB.::GO:0048265; P:response to pain; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB.
87Q4R4U2    697   KPCG_MACFA Protein kinase C gamma type OS=Mac...1090.0005     48.5     31     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.
88P70611    403   DOC2A_RAT Double C2-like domain-containing pr...1350.001     46.6     30     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0016079; P:synaptic vesicle exocytosis; IEP:RGD.
89Q7TNF0    405   DOC2A_MOUSE Double C2-like domain-containing ...1350.0006     47.8     31     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.
90Q9ZT46    138   PP16B_CUCMA 16 kDa phloem protein 2 OS=Cucurb...950.0005     45.4     31     47
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.
91Q14183    400   DOC2A_HUMAN Double C2-like domain-containing ...1040.001     47     35     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.
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