Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML072C
Length:
1545
Number of sequences:
5887
Description:
YML072C TCB3 SGDID:S000004537, Chr XIII from 129367-124730, Genome Release 64-1-1, reverse complement, Verified ORF, "Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O08625    523   SYT10_RAT Synaptotagmin-10 OS=Rattus norvegic...1060.93     37.7     31     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0050803; P:regulation of synapse structure and activity; NAS:RGD.::GO:0006950; P:response to stress; IEP:RGD.
32Q9R0N4    523   SYT10_MOUSE Synaptotagmin-10 OS=Mus musculus ...1061     37.4     31     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
33P24506    439   SY62_DISOM Synaptotagmin-B OS=Discopyge ommat...970.005     44.7     37     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
34Q5RCK6    523   SYT10_PONAB Synaptotagmin-10 OS=Pongo abelii ...941     37.4     29     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
35Q6XYQ8    523   SYT10_HUMAN Synaptotagmin-10 OS=Homo sapiens ...941.2     37.4     29     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
36O43581    403   SYT7_HUMAN Synaptotagmin-7 OS=Homo sapiens (H...1310.012     43.5     27     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
37Q9R0N7    403   SYT7_MOUSE Synaptotagmin-7 OS=Mus musculus (M...1310.017     43.1     26     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0001778; P:plasma membrane repair; IDA:MGI.
38O00445    386   SYT5_HUMAN Synaptotagmin-5 OS=Homo sapiens (H...891.2     37     34     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:ProtInc.
39Q6DN12    878   MCTP2_HUMAN Multiple C2 and transmembrane dom...722.6     36.2     32     50GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; IDA:HGNC.
GO:0005509; F:calcium ion binding; IDA:HGNC.
GO:0019722; P:calcium-mediated signaling; NAS:HGNC.
40C9J798    803   RAS4B_HUMAN Putative Ras GTPase-activating pr...840.001     47.4     30     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
41O43374    803   RASL2_HUMAN Ras GTPase-activating protein 4 O...840.001     47.4     30     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
42O95294    804   RASL1_HUMAN RasGAP-activating-like protein 1 ...2232.2     36.6     23     42GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
43Q60HC0    419   SYT1_MACFA Synaptotagmin-1 OS=Macaca fascicul...1040.004     45.1     36     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
44P21579    422   SYT1_HUMAN Synaptotagmin-1 OS=Homo sapiens (H...1040.004     45.4     36     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0060201; C:clathrin sculpted acetylcholine transport vesicle membrane; TAS:Reactome.::GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome.::GO:0060203; C:clathrin sculpted glutamate transport vesicle membrane; TAS:Reactome.::GO:0070083; C:clathrin sculpted monoamine transport vesicle membrane; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; TAS:UniProtKB.::GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.::GO:0017075; F:syntaxin-1 binding; TAS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0005513; P:detection of calcium ion; TAS:UniProtKB.::GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0051260; P:protein homooligomerization; TAS:UniProtKB.
45P21707    421   SYT1_RAT Synaptotagmin-1 OS=Rattus norvegicus...1040.003     45.4     36     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0031045; C:dense core granule; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD.
GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; TAS:RGD.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:RGD.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.
46P46096    421   SYT1_MOUSE Synaptotagmin-1 OS=Mus musculus (M...1040.003     45.4     36     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:UniProtKB.::GO:0042734; C:presynaptic membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IDA:MGI.
GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005544; F:calcium-dependent phospholipid binding; TAS:MGI.::GO:0048306; F:calcium-dependent protein binding; IPI:HGNC.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0016079; P:synaptic vesicle exocytosis; IMP:MGI.
47P48018    422   SYT1_BOVIN Synaptotagmin-1 OS=Bos taurus (Bov...1040.004     45.4     36     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
48Q9Y6V0    5065   PCLO_HUMAN Protein piccolo OS=Homo sapiens (H...1090.000007     55.1     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; NAS:UniProtKB.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; NAS:UniProtKB.
49P05130    679   KPC1_DROME Protein kinase C, brain isozyme OS...1090.000007     54.3     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
50Q9R0N5    386   SYT5_MOUSE Synaptotagmin-5 OS=Mus musculus (M...930.25     39.3     33     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
51Q6PFQ7    802   RASL2_MOUSE Ras GTPase-activating protein 4 O...890.0002     50.1     30     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
52P47861    386   SYT5_RAT Synaptotagmin-5 OS=Rattus norvegicus...960.17     40     32     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; NAS:RGD.
53Q9Z268    799   RASL1_MOUSE RasGAP-activating-like protein 1 ...2281.6     37     23     40GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
54P90980    682   KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh...1290.00001     53.5     32     44GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
55Q9PU36    5120   PCLO_CHICK Protein piccolo OS=Gallus gallus (...1160.00002     53.9     31     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
56Q9JKS6    5085   PCLO_RAT Protein piccolo OS=Rattus norvegicus...1180.00002     53.5     31     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB.
57P46097    422   SYT2_MOUSE Synaptotagmin-2 OS=Mus musculus (M...2486.5     34.7     24     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0042598; C:vesicular fraction; IDA:MGI.
GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005215; F:transporter activity; IEA:InterPro.
58Q5RJH2    878   MCTP2_MOUSE Multiple C2 and transmembrane dom...641.2     37.4     36     53GO:0016021; C:integral to membrane; ISS:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC.
GO:0005509; F:calcium ion binding; ISS:HGNC.
59Q62940    887   NEDD4_RAT E3 ubiquitin-protein ligase NEDD4 O...1910.0003     49.3     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0006955; P:immune response; IEP:RGD.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB.
60P47191    424   SYT1_CHICK Synaptotagmin-1 OS=Gallus gallus (...1040.008     44.3     35     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
61Q9QYX7    5038   PCLO_MOUSE Protein piccolo OS=Mus musculus (M...1180.00003     53.1     31     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; IDA:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB.
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