Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML068W
Length:
464
Number of sequences:
5887
Description:
YML068W ITT1 SGDID:S000004533, Chr XIII from 137550-138944, Genome Release 64-1-1, Verified ORF, "Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q32NS4    529   ARI1_XENLA E3 ubiquitin-protein ligase arih1 ...2430.0006     45.8     23     38GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
32B1H1E4    529   ARI1_XENTR E3 ubiquitin-protein ligase arih1 ...2430.0006     45.8     22     37GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
33Q9Y4X5    557   ARI1_HUMAN E3 ubiquitin-protein ligase ARIH1 ...1860.0006     45.8     24     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0000151; C:ubiquitin ligase complex; TAS:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
34Q9Z1K5    555   ARI1_MOUSE E3 ubiquitin-protein ligase ARIH1 ...1860.0006     45.8     24     40GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IPI:MGI.
35A2VEA3    555   ARI1_BOVIN E3 ubiquitin-protein ligase ARIH1 ...1860.0006     45.8     24     40GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
36Q6NW85    533   ARI1L_DANRE E3 ubiquitin-protein ligase arih1...2430.0007     45.8     23     38GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
37Q9LVX0    537   ARI3_ARATH Probable E3 ubiquitin-protein liga...2640.001     45.1     23     37
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
38E6ZIJ1    707   HOIL1_DICLA RanBP-type and C3HC4-type zinc fi...1800.001     45.1     23     38GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
39Q1L8G6    1060   AKIB1_DANRE Ankyrin repeat and IBR domain-con...2670.002     44.7     23     37
GO:0008270; F:zinc ion binding; IEA:InterPro.
40Q8BKD6    301   R144B_MOUSE E3 ubiquitin-protein ligase RNF14...2290.002     43.5     22     35GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.
41A5PK27    304   R144B_BOVIN E3 ubiquitin-protein ligase RNF14...2280.002     43.5     21     36GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.
42P36113    551   YKZ7_YEAST RING finger protein YKR017C OS=Sac...2640.002     43.9     23     38
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
43Q9P3U4    504   YKX2_SCHPO Uncharacterized RING finger protei...350.003     43.9     43     66GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007127; P:meiosis I; IEP:PomBase.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; TAS:PomBase.
44Q7Z419    303   R144B_HUMAN E3 ubiquitin-protein ligase RNF14...2320.007     42     21     36GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IC:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
45Q9SKC3    543   ARI9_ARATH Probable E3 ubiquitin-protein liga...360.007     42.4     47     69
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
46Q9BYM8    510   HOIL1_HUMAN RanBP-type and C3HC4-type zinc fi...520.009     42     33     62GO:0071797; C:LUBAC complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
47Q94981    503   ARI1_DROME Protein ariadne-1 OS=Drosophila me...2820.014     41.6     23     34GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
48Q6GZQ2    324   073L_FRG3G Uncharacterized protein 073L OS=Fr...430.015     41.2     44     60GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
49Q6T486    520   RBRA_DICDI Probable E3 ubiquitin-protein liga...2630.018     41.2     21     34
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
50Q9WUB0    508   HOIL1_MOUSE RanBP-type and C3HC4-type zinc fi...1320.021     40.8     27     40GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
51O76924    509   ARI2_DROME Protein ariadne-2 OS=Drosophila me...664.6     33.5     33     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
52Q62921    508   HOIL1_RAT RanBP-type and C3HC4-type zinc fing...520.035     40     31     62GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
53Q2VJ60    838   RN19A_PIG E3 ubiquitin-protein ligase RNF19A ...2430.042     40     21     35GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
54Q9NWF9    866   RN216_HUMAN E3 ubiquitin-protein ligase RNF21...520.043     40     37     60GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; IDA:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IDA:UniProtKB.
55P50636    840   RN19A_MOUSE E3 ubiquitin-protein ligase RNF19...2430.045     40     21     35GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
56P58283    853   RN216_MOUSE E3 ubiquitin-protein ligase RNF21...520.045     40     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; ISS:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; ISS:UniProtKB.
57Q9NV58    838   RN19A_HUMAN E3 ubiquitin-protein ligase RNF19...2430.046     40     21     35GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0000226; P:microtubule cytoskeleton organization; TAS:UniProtKB.::GO:0006464; P:protein modification process; NAS:UniProtKB.
58Q22431    482   ARI2_CAEEL Probable protein ariadne-2 OS=Caen...3390.058     39.3     19     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
59Q9JK66    465   PRKN2_RAT E3 ubiquitin-protein ligase parkin ...1160.18     37.7     28     38GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0008021; C:synaptic vesicle; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042551; P:neuron maturation; IEP:RGD.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006986; P:response to unfolded protein; IDA:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
60Q9WVS6    464   PRKN2_MOUSE E3 ubiquitin-protein ligase parki...1160.24     37.4     28     41GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0043234; C:protein complex; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042417; P:dopamine metabolic process; IMP:MGI.::GO:0051583; P:dopamine uptake; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042415; P:norepinephrine metabolic process; IMP:MGI.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:MGI.::GO:0001964; P:startle response; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
61Q9SKC2    542   ARI11_ARATH Probable E3 ubiquitin-protein lig...310.45     36.6     48     61
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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