Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML065W
Length:
914
Number of sequences:
5887
Description:
YML065W ORC1 SGDID:S000004530, Chr XIII from 142210-144954, Genome Release 64-1-1, Verified ORF, "Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P54784    914   ORC1_YEAST Origin recognition complex subunit...9140     1885     100     100GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0005664; C:nuclear origin of replication recognition complex; IMP:SGD.::GO:0005656; C:pre-replicative complex; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IMP:SGD.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IDA:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.
2P54788    886   ORC1_KLULA Origin recognition complex subunit...9490     751     46     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
3Q6BSE2    810   ORC1_DEBHA Origin recognition complex subunit...9578e-110     363     31     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
4O74270    805   ORC1_CANAX Origin recognition complex subunit...8264e-92     315     31     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
5P54789    707   ORC1_SCHPO Origin recognition complex subunit...4734e-67     243     32     52GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0003688; F:DNA replication origin binding; IDA:UniProtKB.
GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:PomBase.
6P06701    978   SIR3_YEAST Regulatory protein SIR3 OS=Sacchar...4082e-33     142     28     47GO:0005677; C:chromatin silencing complex; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000783; C:nuclear telomere cap complex; IDA:SGD.::GO:0005724; C:nuclear telomeric heterochromatin; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.
GO:0003690; F:double-stranded DNA binding; IDA:SGD.::GO:0031493; F:nucleosomal histone binding; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IPI:SGD.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.::GO:0030527; F:structural constituent of chromatin; TAS:SGD.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IDA:SGD.::GO:0031507; P:heterochromatin assembly; IMP:SGD.::GO:0001308; P:negative regulation of chromatin silencing involved in replicative cell aging; IDA:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7O16810    924   ORC1_DROME Origin recognition complex subunit...3898e-54     206     30     48GO:0005664; C:nuclear origin of replication recognition complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0006277; P:DNA amplification; IMP:FlyBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:FlyBase.
8Q9JI69    850   ORC1_CRIGR Origin recognition complex subunit...4721e-51     198     29     49GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
9Q9Z1N2    840   ORC1_MOUSE Origin recognition complex subunit...4715e-51     196     29     48GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; TAS:MGI.
10Q80Z32    848   ORC1_RAT Origin recognition complex subunit 1...4712e-50     195     30     48GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
11Q13415    861   ORC1_HUMAN Origin recognition complex subunit...4712e-50     195     30     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0006270; P:DNA-dependent DNA replication initiation; TAS:ProtInc.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
12Q58DC8    863   ORC1_BOVIN Origin recognition complex subunit...4713e-48     188     29     48GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13Q54RM2    631   ORC1_DICDI Origin recognition complex subunit...3135e-43     170     35     54GO:0005634; C:nucleus; ISS:dictyBase.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; ISS:dictyBase.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006270; P:DNA-dependent DNA replication initiation; ISS:dictyBase.
14Q8I615    1189   ORC1_PLAF7 Origin recognition complex subunit...2751e-37     156     32     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
15O89033    562   CDC6_MOUSE Cell division control protein 6 ho...3014e-27     120     26     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
16P41411    577   CDC18_SCHPO Cell division control protein 18 ...2912e-26     119     27     49GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003689; F:DNA clamp loader activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0006267; P:pre-replicative complex assembly; ISS:PomBase.
17Q99741    560   CDC6_HUMAN Cell division control protein 6 ho...3007e-26     116     26     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0051233; C:spindle midzone; IDA:BHF-UCL.::GO:0000922; C:spindle pole; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:Reactome.::GO:0000076; P:DNA replication checkpoint; TAS:ProtInc.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0008156; P:negative regulation of DNA replication; TAS:ProtInc.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:BHF-UCL.::GO:0051984; P:positive regulation of chromosome segregation; IDA:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0090007; P:regulation of mitotic anaphase; IMP:BHF-UCL.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
18Q4JAS8    397   CDC61_SULAC Cell division control protein 6 h...3120.00000000001     70.9     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
19Q8PXA8    414   CDC61_METMA Cell division control protein 6 h...3070.00000000005     69.3     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
20Q975X3    398   CDC61_SULTO Cell division control protein 6 h...3100.0000000001     67.8     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
21P09119    513   CDC6_YEAST Cell division control protein 6 OS...3540.0000000002     68.2     23     41GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005656; C:pre-replicative complex; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.
22Q9V2F2    419   CDC6_PYRAB Cell division control protein 6 ho...3740.0000000002     67.4     24     43
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:HAMAP.
23Q8TUR2    414   CDC61_METAC Cell division control protein 6 h...3070.0000000007     65.9     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
24O57864    419   CDC6_PYRHO Cell division control protein 6 ho...3020.0000000008     65.9     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
25B6YUE9    415   CDC6_THEON Cell division control protein 6 ho...3020.0000000008     65.5     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
26P81413    420   CDC6_PYRFU Cell division control protein 6 ho...3750.000000001     65.5     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
27Q980N4    397   CDC61_SULSO Cell division control protein 6 h...3320.000000004     63.2     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
28Q5UZ24    524   CDC64_HALMA Cell division control protein 6 h...3400.00000001     62     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
29Q5JET2    415   CDC6_PYRKO Cell division control protein 6 ho...2960.00000002     61.6     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
30A2SPC3    425   CDC6_METLZ Cell division control protein 6 ho...3120.00000002     61.2     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
31O29995    409   CDC61_ARCFU Cell division control protein 6 h...2830.00000005     60.1     22     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
records
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