Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML057W
Length:
604
Number of sequences:
5887
Description:
YML057W CMP2 SGDID:S000004521, Chr XIII from 160180-161994, Genome Release 64-1-1, Verified ORF, "Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P14747    604   PP2B2_YEAST Serine/threonine-protein phosphat...6040     1264     100     100GO:0005955; C:calcineurin complex; IDA:SGD.::GO:0005737; C:cytoplasm; TAS:SGD.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0006873; P:cellular ion homeostasis; IMP:SGD.
2P23287    553   PP2B1_YEAST Serine/threonine-protein phosphat...5440     763     67     80GO:0005955; C:calcineurin complex; IDA:SGD.::GO:0005737; C:cytoplasm; TAS:SGD.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0006873; P:cellular ion homeostasis; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.
3Q05681    558   PP2B_NEUCR Serine/threonine-protein phosphata...6020     615     51     67
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
4P48457    549   PP2B_EMENI Serine/threonine-protein phosphata...5560     614     53     70
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
5Q4WUR1    534   PP2B_ASPFU Serine/threonine-protein phosphata...5470     603     53     70
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
6Q12705    554   PP2B_SCHPO Serine/threonine-protein phosphata...5660     599     53     68GO:0005955; C:calcineurin complex; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IMP:PomBase.
GO:0019722; P:calcium-mediated signaling; IMP:PomBase.::GO:0030644; P:cellular chloride ion homeostasis; TAS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IGI:PomBase.::GO:0006470; P:protein dephosphorylation; IC:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.::GO:0070631; P:spindle pole body localization; IMP:PomBase.
7O42773    639   PP2B1_CRYNV Serine/threonine-protein phosphat...5510     584     53     68
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
8P48456    622   PP2B1_DROME Serine/threonine-protein phosphat...5430     556     53     66GO:0008021; C:synaptic vesicle; NAS:FlyBase.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; NAS:FlyBase.
GO:0072375; P:medium-term memory; IDA:FlyBase.::GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0006470; P:protein dephosphorylation; NAS:FlyBase.::GO:0030431; P:sleep; IDA:FlyBase.::GO:0016192; P:vesicle-mediated transport; NAS:FlyBase.
9Q08209    521   PP2BA_HUMAN Serine/threonine-protein phosphat...5380     546     51     67GO:0005955; C:calcineurin complex; NAS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; TAS:UniProtKB.::GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IDA:UniProtKB.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; NAS:UniProtKB.::GO:0042110; P:T cell activation; TAS:UniProtKB.
10P48452    521   PP2BA_BOVIN Serine/threonine-protein phosphat...5380     546     51     67GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
11P63329    521   PP2BA_RAT Serine/threonine-protein phosphatas...5380     546     51     67GO:0005955; C:calcineurin complex; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; IDA:RGD.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.
GO:0071333; P:cellular response to glucose stimulus; IMP:BHF-UCL.::GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IC:BHF-UCL.::GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.::GO:0006470; P:protein dephosphorylation; IDA:RGD.::GO:0001975; P:response to amphetamine; IEP:RGD.
12P63328    521   PP2BA_MOUSE Serine/threonine-protein phosphat...5380     546     51     67GO:0005955; C:calcineurin complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005792; C:microsome; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0030018; C:Z disc; IDA:MGI.
GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; TAS:Reactome.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0033173; P:calcineurin-NFAT signaling cascade; IDA:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006606; P:protein import into nucleus; IDA:MGI.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IGI:MGI.::GO:0050804; P:regulation of synaptic transmission; IMP:MGI.::GO:0006950; P:response to stress; IDA:MGI.::GO:0048741; P:skeletal muscle fiber development; IMP:MGI.::GO:0014883; P:transition between fast and slow fiber; IDA:MGI.
13Q27889    570   PP2B2_DROME Serine/threonine-protein phosphat...5280     545     52     67
GO:0005516; F:calmodulin binding; TAS:FlyBase.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; IMP:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009790; P:embryo development; IMP:FlyBase.::GO:0007143; P:female meiosis; IMP:FlyBase.::GO:0006470; P:protein dephosphorylation; NAS:FlyBase.::GO:0030431; P:sleep; IDA:FlyBase.::GO:0035220; P:wing disc development; IMP:FlyBase.
14P20651    525   PP2BB_RAT Serine/threonine-protein phosphatas...5340     533     50     65GO:0005955; C:calcineurin complex; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; ISS:UniProtKB.::GO:0008144; F:drug binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0030346; F:protein phosphatase 2B binding; ISS:UniProtKB.
GO:0017156; P:calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0046716; P:muscle cell homeostasis; IEP:RGD.::GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:RGD.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.::GO:0001975; P:response to amphetamine; IEP:RGD.
15P48453    525   PP2BB_MOUSE Serine/threonine-protein phosphat...5340     533     50     65GO:0005955; C:calcineurin complex; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; IMP:UniProtKB.::GO:0008144; F:drug binding; ISS:UniProtKB.::GO:0030346; F:protein phosphatase 2B binding; ISS:UniProtKB.
GO:0017156; P:calcium ion-dependent exocytosis; IDA:UniProtKB.::GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.::GO:0006468; P:protein phosphorylation; IMP:UniProtKB.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0034097; P:response to cytokine stimulus; IMP:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0043029; P:T cell homeostasis; IMP:MGI.
16P16298    524   PP2BB_HUMAN Serine/threonine-protein phosphat...5340     533     50     65GO:0005955; C:calcineurin complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; ISS:UniProtKB.::GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0030346; F:protein phosphatase 2B binding; IDA:UniProtKB.
GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0017156; P:calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0007612; P:learning; TAS:UniProtKB.::GO:0007613; P:memory; TAS:UniProtKB.::GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.::GO:0048167; P:regulation of synaptic plasticity; TAS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0035176; P:social behavior; IEP:UniProtKB.::GO:0042098; P:T cell proliferation; NAS:UniProtKB.
17Q9VXF1    584   PP2B3_DROME Serine/threonine-protein phosphat...5270     535     51     66
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; IMP:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0006470; P:protein dephosphorylation; NAS:FlyBase.::GO:0030431; P:sleep; IDA:FlyBase.
18Q7YSW8    623   PP2BA_DICDI Calcineurin subunit A OS=Dictyost...5758e-180     530     48     63GO:0005955; C:calcineurin complex; IC:dictyBase.
GO:0005509; F:calcium ion binding; ISS:dictyBase.::GO:0005516; F:calmodulin binding; IDA:dictyBase.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:dictyBase.
GO:0006470; P:protein dephosphorylation; IDA:dictyBase.
19P48454    512   PP2BC_HUMAN Serine/threonine-protein phosphat...5359e-179     523     50     65GO:0005829; C:cytosol; TAS:Reactome.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.
20P48455    513   PP2BC_MOUSE Serine/threonine-protein phosphat...5293e-175     514     49     64
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
21P48488    321   PP1_MEDSV Serine/threonine-protein phosphatas...3002e-65     223     39     57
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
22O04857    310   PP12_TOBAC Serine/threonine-protein phosphata...3103e-65     222     38     56
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
23P48484    321   PP14_ARATH Serine/threonine-protein phosphata...3027e-65     221     38     58
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0006470; P:protein dephosphorylation; TAS:TAIR.
24P48480    319   PP11_ACECL Serine/threonine-protein phosphata...3022e-64     220     37     58
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
25P48483    322   PP13_ARATH Serine/threonine-protein phosphata...3043e-64     219     38     57GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0006470; P:protein dephosphorylation; TAS:TAIR.
26P48489    322   PP1_ORYSJ Serine/threonine-protein phosphatas...3021e-63     218     37     58
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
27P22198    316   PP1_MAIZE Serine/threonine-protein phosphatas...3021e-63     218     36     57
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
28P30366    318   PP11_ARATH Serine/threonine-protein phosphata...2982e-63     218     38     57
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0006470; P:protein dephosphorylation; IGI:TAIR.
29P23734    346   PP12_TRYBB Serine/threonine-protein phosphata...3683e-63     218     34     54
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
30P48482    312   PP12_ARATH Serine/threonine-protein phosphata...3025e-63     216     35     59
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0006470; P:protein dephosphorylation; TAS:TAIR.
31P48486    322   PP16_ARATH Serine/threonine-protein phosphata...3037e-63     216     37     56
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
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