Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML027W
Length:
385
Number of sequences:
5887
Description:
YML027W YOX1 SGDID:S000004489, Chr XIII from 221406-222563, Genome Release 64-1-1, Verified ORF, "Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P34161    385   YOX1_YEAST Homeobox protein YOX1 OS=Saccharom...3850     768     100     100GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IMP:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0060277; P:negative regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.
2Q04116    353   YHP1_YEAST Homeobox protein YHP1 OS=Saccharom...4032e-48     173     37     55GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IPI:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0060277; P:negative regulation of transcription involved in G1 phase of mitotic cell cycle; IGI:SGD.
3Q54PU1    638   HBX10_DICDI Homeobox protein 10 OS=Dictyostel...570.0000000005     64.7     49     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q7T103    449   P5F11_XENLA POU domain, class 5, transcriptio...900.00000006     58.2     31     59GO:0005667; C:transcription factor complex; IPI:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0046332; F:SMAD binding; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IMP:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0045605; P:negative regulation of epidermal cell differentiation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050767; P:regulation of neurogenesis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5B3DM25    459   P5F11_XENTR POU domain, class 5, transcriptio...1220.0000002     56.2     27     52GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0007369; P:gastrulation; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0045605; P:negative regulation of epidermal cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050767; P:regulation of neurogenesis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6P20264    500   PO3F3_HUMAN POU domain, class 3, transcriptio...940.0000005     55.1     34     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0072218; P:metanephric ascending thin limb development; ISS:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; ISS:UniProtKB.::GO:0072227; P:metanephric macula densa development; ISS:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7P79745    443   P3F3B_DANRE POU domain, class 3, transcriptio...1120.0000005     55.1     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8P31361    497   PO3F3_MOUSE POU domain, class 3, transcriptio...940.0000005     55.1     34     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0021799; P:cerebral cortex radially oriented cell migration; IGI:MGI.::GO:0021869; P:forebrain ventricular zone progenitor cell division; IGI:MGI.::GO:0072218; P:metanephric ascending thin limb development; IMP:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; IMP:UniProtKB.::GO:0072227; P:metanephric macula densa development; IMP:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q63262    497   PO3F3_RAT POU domain, class 3, transcription ...940.0000005     55.1     34     55GO:0005634; C:nucleus; IMP:UniProtKB.
GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0072218; P:metanephric ascending thin limb development; ISS:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; ISS:UniProtKB.::GO:0072227; P:metanephric macula densa development; ISS:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.
10P06602    376   EVE_DROME Segmentation protein even-skipped O...710.0000009     53.9     38     56GO:0005634; C:nucleus; IDA:FlyBase.
GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.
GO:0008595; P:anterior/posterior axis specification, embryo; NAS:FlyBase.::GO:0001709; P:cell fate determination; NAS:FlyBase.::GO:0007417; P:central nervous system development; NAS:FlyBase.::GO:0007376; P:cephalic furrow formation; IMP:FlyBase.::GO:0007377; P:germ-band extension; IMP:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007517; P:muscle organ development; TAS:FlyBase.::GO:0009997; P:negative regulation of cardioblast cell fate specification; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0007366; P:periodic partitioning by pair rule gene; NAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEP:FlyBase.::GO:0035289; P:posterior head segmentation; TAS:FlyBase.::GO:0050770; P:regulation of axonogenesis; IMP:FlyBase.::GO:0035290; P:trunk segmentation; TAS:FlyBase.
11P78424    691   PO6F2_HUMAN POU domain, class 6, transcriptio...640.0000009     54.3     44     63GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0007402; P:ganglion mother cell fate determination; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
12Q99160    509   HOY1_YARLI Homeobox protein HOY1 OS=lipolytic...550.000001     53.9     40     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
13P20265    443   PO3F2_HUMAN POU domain, class 3, transcriptio...670.000001     53.5     39     63
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
14P31360    445   PO3F2_MOUSE POU domain, class 3, transcriptio...670.000001     53.5     39     63GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
GO:0014002; P:astrocyte development; IMP:MGI.::GO:0071310; P:cellular response to organic substance; IDA:MGI.::GO:0021799; P:cerebral cortex radially oriented cell migration; IGI:MGI.::GO:0008544; P:epidermis development; IMP:MGI.::GO:0021869; P:forebrain ventricular zone progenitor cell division; IGI:MGI.::GO:0021979; P:hypothalamus cell differentiation; IMP:MGI.::GO:0022011; P:myelination in peripheral nervous system; IGI:MGI.::GO:0021985; P:neurohypophysis development; IMP:MGI.::GO:0030182; P:neuron differentiation; IDA:MGI.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:MGI.::GO:0050770; P:regulation of axonogenesis; IMP:MGI.
15Q8BJI4    691   PO6F2_MOUSE POU domain, class 6, transcriptio...640.000001     53.9     44     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P70030    385   P3F2B_XENLA POU domain, class 3, transcriptio...670.000002     53.1     37     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17P56222    445   PO3F2_RAT POU domain, class 3, transcription ...670.000002     52.8     39     63
GO:0071837; F:HMG box domain binding; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.
18P40923    201   YHZD_SCHPO Uncharacterized homeobox protein C...650.000003     51.2     42     65GO:0030907; C:MBF transcription complex; NAS:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IMP:PomBase.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; NAS:PomBase.
GO:0071930; P:negative regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:PomBase.
19P07269    559   PHO2_YEAST Regulatory protein PHO2 OS=Sacchar...660.000003     52.8     36     64GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:SGD.
GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0000105; P:histidine biosynthetic process; IMP:SGD.::GO:0043388; P:positive regulation of DNA binding; IDA:SGD.::GO:0045937; P:positive regulation of phosphate metabolic process; IGI:SGD.::GO:0009113; P:purine base biosynthetic process; IDA:SGD.
20P56224    438   P3F3A_DANRE POU domain, class 3, transcriptio...670.000003     52.4     37     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21P31365    382   P3F2A_XENLA POU domain, class 3, transcriptio...670.000003     52.4     39     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22A1L0Z1    360   PO3F4_XENTR POU domain, class 3, transcriptio...670.000004     52     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q8SW18    227   HD10_ENCCU Homeobox protein HD-10 OS=Encephal...600.000005     50.8     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
24Q812B1    361   PO3F4_MESAU POU domain, class 3, transcriptio...670.000005     51.6     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25P16241    427   CF1A_DROME POU domain protein CF1A OS=Drosoph...1060.000005     51.6     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:FlyBase.
GO:0035284; P:brain segmentation; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; TAS:FlyBase.::GO:0007425; P:epithelial cell fate determination, open tracheal system; TAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.
26P49335    361   PO3F4_HUMAN POU domain, class 3, transcriptio...670.000005     51.6     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; TAS:ProtInc.
27P62516    361   PO3F4_RAT POU domain, class 3, transcription ...670.000006     51.6     37     61GO:0005634; C:nucleus; IDA:RGD.
GO:0003680; F:AT DNA binding; IDA:RGD.::GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.
GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.::GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:RGD.
28P62515    361   PO3F4_MOUSE POU domain, class 3, transcriptio...670.000006     51.6     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0090103; P:cochlea morphogenesis; IGI:UniProtKB.::GO:0021879; P:forebrain neuron differentiation; IMP:MGI.::GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; IGI:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:MGI.
29Q9IA25    208   HXA7_HETFR Homeobox protein Hox-A7 OS=Heterod...770.000006     50.1     35     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q54F46    803   WARA_DICDI Homeobox protein Wariai OS=Dictyos...530.000006     52     43     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045595; P:regulation of cell differentiation; IMP:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31Q93899    247   VAB7_CAEEL Homeobox protein vab-7 OS=Caenorha...1120.000007     50.4     30     47GO:0005634; C:nucleus; IDA:WormBase.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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