Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML027W
Length:
385
Number of sequences:
5887
Description:
YML027W YOX1 SGDID:S000004489, Chr XIII from 221406-222563, Genome Release 64-1-1, Verified ORF, "Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421P43699    371   NKX21_HUMAN Homeobox protein Nkx-2.1 OS=Homo ...590.002     43.1     42     58
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEP:UniProtKB.::GO:0021759; P:globus pallidus development; IMP:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0009725; P:response to hormone stimulus; IEP:UniProtKB.::GO:0030878; P:thyroid gland development; IMP:UniProtKB.
422P56179    175   DLX6_HUMAN Homeobox protein DLX-6 OS=Homo sap...570.002     42     39     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0001501; P:skeletal system development; TAS:ProtInc.
423O35762    365   NKX61_RAT Homeobox protein Nkx-6.1 OS=Rattus ...640.002     43.1     34     55GO:0005634; C:nucleus; IDA:RGD.
GO:0003682; F:chromatin binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:RGD.::GO:0071345; P:cellular response to cytokine stimulus; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IEP:RGD.::GO:0032024; P:positive regulation of insulin secretion; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0035094; P:response to nicotine; IEP:RGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IMP:RGD.::GO:0003323; P:type B pancreatic cell development; IEP:RGD.
424P50220    372   NKX21_MOUSE Homeobox protein Nkx-2.1 OS=Mus m...590.002     43.1     42     58GO:0005625; C:soluble fraction; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0048646; P:anatomical structure formation involved in morphogenesis; IMP:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0021892; P:cerebral cortex GABAergic interneuron differentiation; IMP:MGI.::GO:0060486; P:Clara cell differentiation; IGI:MGI.::GO:0031128; P:developmental induction; IMP:MGI.::GO:0007492; P:endoderm development; IMP:MGI.::GO:0021798; P:forebrain dorsal/ventral pattern formation; IMP:MGI.::GO:0021877; P:forebrain neuron fate commitment; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0033327; P:Leydig cell differentiation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060430; P:lung saccule development; IGI:MGI.::GO:0042696; P:menarche; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0048709; P:oligodendrocyte differentiation; IGI:MGI.::GO:0006644; P:phospholipid metabolic process; IGI:MGI.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030878; P:thyroid gland development; IMP:MGI.::GO:0060510; P:Type II pneumocyte differentiation; IGI:MGI.
425P50222    304   MEOX2_HUMAN Homeobox protein MOX-2 OS=Homo sa...750.002     43.1     33     60GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0008015; P:blood circulation; TAS:ProtInc.
426P23441    372   NKX21_RAT Homeobox protein Nkx-2.1 OS=Rattus ...590.002     43.1     42     58
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.
GO:0046545; P:development of primary female sexual characteristics; IEP:RGD.::GO:0007631; P:feeding behavior; IMP:RGD.::GO:0042538; P:hyperosmotic salinity response; IDA:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0002016; P:regulation of blood volume by renin-angiotensin; IDA:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.
427Q9H2Z4    354   NKX24_HUMAN Homeobox protein Nkx-2.4 OS=Homo ...590.002     43.1     42     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
428Q93V99    743   PDF2_ARATH Homeobox-leucine zipper protein PR...610.002     43.5     31     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0048825; P:cotyledon development; IGI:TAIR.::GO:0009913; P:epidermal cell differentiation; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
429Q9IA11    252   HXD5_HETFR Homeobox protein Hox-D5 OS=Heterod...790.003     42.7     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
430Q99MA9    365   NKX61_MOUSE Homeobox protein Nkx-6.1 OS=Mus m...640.003     43.1     34     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0045686; P:negative regulation of glial cell differentiation; IGI:MGI.::GO:0048709; P:oligodendrocyte differentiation; IGI:MGI.::GO:0045687; P:positive regulation of glial cell differentiation; IGI:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IDA:MGI.::GO:0021912; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; IGI:MGI.::GO:0021913; P:regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; IMP:MGI.::GO:0007224; P:smoothened signaling pathway; IDA:MGI.
431Q68G74    356   LHX8_HUMAN LIM/homeobox protein Lhx8 OS=Homo ...830.003     43.1     30     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
432Q99697    317   PITX2_HUMAN Pituitary homeobox 2 OS=Homo sapi...600.003     43.1     38     63GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0051219; F:phosphoprotein binding; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0043021; F:ribonucleoprotein complex binding; IC:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
GO:0003253; P:cardiac neural crest cell migration involved in outflow tract morphogenesis; ISS:BHF-UCL.::GO:0061325; P:cell proliferation involved in outflow tract morphogenesis; ISS:BHF-UCL.::GO:0035993; P:deltoid tuberosity development; IMP:BHF-UCL.::GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.::GO:0035315; P:hair cell differentiation; IC:BHF-UCL.::GO:0061072; P:iris morphogenesis; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0042476; P:odontogenesis; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0060127; P:prolactin secreting cell differentiation; TAS:BHF-UCL.::GO:0060126; P:somatotropin secreting cell differentiation; TAS:BHF-UCL.
433Q60554    364   NKX61_MESAU Homeobox protein Nkx-6.1 OS=Mesoc...640.003     43.1     34     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0051594; P:detection of glucose; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:2000078; P:positive regulation of type B pancreatic cell development; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072560; P:type B pancreatic cell maturation; IMP:BHF-UCL.
434P32443    303   MEOX2_MOUSE Homeobox protein MOX-2 OS=Mus mus...570.003     43.1     33     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0060173; P:limb development; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0007519; P:skeletal muscle tissue development; IMP:MGI.::GO:0001757; P:somite specification; IGI:MGI.
435O35085    564   ARX_MOUSE Homeobox protein ARX OS=Mus musculu...710.003     43.5     35     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021846; P:cell proliferation in forebrain; IMP:MGI.::GO:0021853; P:cerebral cortex GABAergic interneuron migration; IMP:MGI.::GO:0021800; P:cerebral cortex tangential migration; IMP:MGI.::GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IMP:MGI.::GO:0021759; P:globus pallidus development; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0046622; P:positive regulation of organ growth; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
436Q6R3Q6    227   BSH_DANRE Brain-specific homeobox protein hom...610.003     42.4     39     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
437Q26430    97   ABDA_MANSE Homeobox protein abdominal-A homol...590.003     40.8     34     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
438P07548    586   DFD_DROME Homeotic protein deformed OS=Drosop...700.003     43.5     30     54GO:0005634; C:nucleus; IDA:FlyBase.
GO:0033613; F:activating transcription factor binding; IPI:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.
GO:0007420; P:brain development; IMP:FlyBase.::GO:0048598; P:embryonic morphogenesis; IMP:FlyBase.::GO:0060322; P:head development; IMP:FlyBase.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.
439Q8QGC4    347   PBX1_XENLA Pre-B-cell leukemia transcription ...610.003     43.1     43     52GO:0005667; C:transcription factor complex; IGI:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014036; P:neural crest cell fate specification; IGI:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
440P15861    228   HXB6A_DANRE Homeobox protein Hox-B6a OS=Danio...590.003     42.4     32     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
441P10179    107   HMB4_TRIGR Homeobox protein HB4 OS=Tripneuste...660.003     40.8     33     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
442Q9PWM3    268   HXC4A_DANRE Homeobox protein Hox-C4a OS=Danio...620.003     42.7     32     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
443A2T7F3    230   HXA7_PANTR Homeobox protein Hox-A7 OS=Pan tro...590.003     42.4     32     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
444P78426    367   NKX61_HUMAN Homeobox protein Nkx-6.1 OS=Homo ...640.003     43.1     34     55GO:0005634; C:nucleus; IDA:HPA.
GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0051594; P:detection of glucose; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:2000078; P:positive regulation of type B pancreatic cell development; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072560; P:type B pancreatic cell maturation; ISS:BHF-UCL.
445Q25132    692   LHX3_HALRO LIM/homeobox protein Lhx3 OS=Haloc...750.003     43.5     27     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
446O18400    509   PITX_DROME Pituitary homeobox homolog Ptx1 OS...600.003     43.1     37     58GO:0005634; C:nucleus; IDA:FlyBase.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
447B4F6V6    347   PBX1_XENTR Pre-B-cell leukemia transcription ...610.003     42.7     43     52GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014036; P:neural crest cell fate specification; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
448Q1KKY0    274   HXB6A_TAKRU Homeobox protein Hox-B6a OS=Takif...590.003     42.7     32     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
449Q90471    262   HXDCA_DANRE Homeobox protein Hox-D12a OS=Dani...700.003     42.7     31     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
450P02830    229   HXA7_MOUSE Homeobox protein Hox-A7 OS=Mus mus...590.003     42.4     32     66GO:0005634; C:nucleus; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0048863; P:stem cell differentiation; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
451Q1KKV2    322   HXCBA_TAKRU Homeobox protein Hox-C11a OS=Taki...600.003     42.7     37     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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