Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML004C
Length:
326
Number of sequences:
5887
Description:
YML004C GLO1 SGDID:S000004463, Chr XIII from 262685-261705, Genome Release 64-1-1, reverse complement, Verified ORF, "Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P50107    326   LGUL_YEAST Lactoylglutathione lyase OS=Saccha...3260     682     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004462; F:lactoylglutathione lyase activity; IGI:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006749; P:glutathione metabolic process; IGI:SGD.::GO:0019243; P:methylglyoxal catabolic process to D-lactate; IDA:SGD.
2Q09751    302   LGUL_SCHPO Lactoylglutathione lyase OS=Schizo...1501e-37     141     45     65GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004462; F:lactoylglutathione lyase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IDA:PomBase.
GO:0071470; P:cellular response to osmotic stress; TAS:PomBase.::GO:0006749; P:glutathione metabolic process; IDA:PomBase.::GO:0019243; P:methylglyoxal catabolic process to D-lactate; IMP:PomBase.
3Q9HU72    176   LGUL_PSEAE Lactoylglutathione lyase OS=12228)...1514e-38     139     48     64
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
4P16635    173   LGUL_PSEPU Lactoylglutathione lyase OS=Pseudo...1472e-36     134     45     63
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
5Q9CPU0    184   LGUL_MOUSE Lactoylglutathione lyase OS=Mus mu...1533e-36     134     46     65
GO:0004462; F:lactoylglutathione lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
6Q6P7Q4    184   LGUL_RAT Lactoylglutathione lyase OS=Rattus n...1478e-36     133     47     65GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004462; F:lactoylglutathione lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0005975; P:carbohydrate metabolic process; IDA:RGD.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0009438; P:methylglyoxal metabolic process; IDA:RGD.
7Q42891    185   LGUL_SOLLC Lactoylglutathione lyase OS=Solanu...1513e-37     137     47     61
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
8Q4R5F2    184   LGUL_MACFA Lactoylglutathione lyase OS=Macaca...1478e-35     130     44     65
GO:0004462; F:lactoylglutathione lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.
9Q8H0V3    185   LGUL_ARATH Lactoylglutathione lyase OS=Arabid...1478e-38     139     47     62GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.
10Q04760    184   LGUL_HUMAN Lactoylglutathione lyase OS=Homo s...1473e-34     129     44     64GO:0005737; C:cytoplasm; TAS:UniProtKB.
GO:0004462; F:lactoylglutathione lyase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
11O04885    185   LGUL_BRAJU Lactoylglutathione lyase OS=Brassi...1505e-37     136     47     63
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
12Q9ZS21    185   LGUL_SOYBN Lactoylglutathione lyase OS=Glycin...1671e-35     132     44     58
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
13O49818    186   LGUL_CICAR Lactoylglutathione lyase OS=Cicer ...1494e-35     131     45     61
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
14Q8W593    350   LGUC_ARATH Probable lactoylglutathione lyase,...1430.000000000000001     79.7     36     52GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0010319; C:stromule; IDA:TAIR.::GO:0031977; C:thylakoid lumen; IDA:TAIR.
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009409; P:response to cold; IEP:TAIR.
15Q948T6    291   LGUL_ORYSJ Lactoylglutathione lyase OS=Oryza ...1510.0000000000004     72     33     50
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
16P0A0T3    138   LGUL_NEIMB Lactoylglutathione lyase OS=Neisse...1483e-17     80.9     36     49
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
17P0A0T2    138   LGUL_NEIMA Lactoylglutathione lyase OS=Neisse...1483e-17     80.9     36     49
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
18Q39366    282   LGUL_BRAOG Putative lactoylglutathione lyase ...1510.000000000000001     79     33     52
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
19P0A1Q2    135   LGUL_SALTY Lactoylglutathione lyase OS=Salmon...1544e-17     80.5     34     46
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
20P0A1Q3    135   LGUL_SALTI Lactoylglutathione lyase OS=Salmon...1544e-17     80.5     34     46
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
21P0AC83    135   LGUL_SHIFL Lactoylglutathione lyase OS=Shigel...1471e-16     79     34     49
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
22P0AC81    135   LGUL_ECOLI Lactoylglutathione lyase OS=Escher...1471e-16     79     34     49
GO:0004462; F:lactoylglutathione lyase activity; IDA:EcoCyc.::GO:0016151; F:nickel cation binding; IDA:EcoCyc.::GO:0042803; F:protein homodimerization activity; IDA:EcoCyc.
GO:0019243; P:methylglyoxal catabolic process to D-lactate; IMP:EcoCyc.
23P0AC82    135   LGUL_ECO57 Lactoylglutathione lyase OS=Escher...1471e-16     79     34     49
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
24Q9KT93    138   LGUL_VIBCH Probable lactoylglutathione lyase ...1432e-17     81.3     36     50
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
25P44638    135   LGUL_HAEIN Lactoylglutathione lyase OS=Haemop...1434e-16     77.8     35     48
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
26Q55595    131   LGUL_SYNY3 Probable lactoylglutathione lyase ...1505e-21     91.3     37     53
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
27P46235    138   LGUL_VIBPA Probable lactoylglutathione lyase ...1432e-17     81.3     34     50
GO:0004462; F:lactoylglutathione lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
28P39586    126   YWBC_BACSU Uncharacterized protein ywbC OS=Ba...1020.009     39.3     27     43
GO:0004462; F:lactoylglutathione lyase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.
29Q9CPV4    298   GLOD4_MOUSE Glyoxalase domain-containing prot...750.22     36.6     31     55GO:0005739; C:mitochondrion; IDA:MGI.
30Q09253    281   GLOD4_CAEEL Glyoxalase 1 OS=Caenorhabditis el...1460.022     39.7     29     47
GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0009438; P:methylglyoxal metabolic process; IMP:UniProtKB.
31Q5I0D1    298   GLOD4_RAT Glyoxalase domain-containing protei...2150.078     38.1     25     39GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
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