rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
871 | Q8BLR7 | 232 | RND1_MOUSE Rho-related GTP-binding protein Rh... | 138 | 0.0000001 | 53.5 | 25 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 872 | Q6NZW8 | 186 | AR8BA_DANRE ADP-ribosylation factor-like prot... | 173 | 0.0000002 | 52.8 | 24 | 53 | GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 873 | Q6TNS7 | 233 | RABL3_DANRE Rab-like protein 3 OS=Danio rerio... | 111 | 0.0000002 | 53.1 | 32 | 51 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 874 | Q32NS2 | 163 | KBRS2_XENLA NF-kappa-B inhibitor-interacting ... | 146 | 0.0000002 | 52 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 875 | Q5REU3 | 201 | ARL4D_PONAB ADP-ribosylation factor-like prot... | 182 | 0.0000002 | 52.8 | 27 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 876 | P49703 | 201 | ARL4D_HUMAN ADP-ribosylation factor-like prot... | 182 | 0.0000002 | 52.8 | 27 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0009306; P:protein secretion; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 877 | Q5S006 | 2527 | LRRK2_MOUSE Leucine-rich repeat serine/threon... | 151 | 0.0000002 | 54.3 | 28 | 48 | GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0005802; C:trans-Golgi network; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0035564; P:regulation of kidney size; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 878 | Q92730 | 232 | RND1_HUMAN Rho-related GTP-binding protein Rh... | 138 | 0.0000002 | 53.1 | 25 | 50 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0016322; P:neuron remodeling; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 879 | Q6GPS4 | 235 | RABL3_XENLA Rab-like protein 3 OS=Xenopus lae... | 215 | 0.0000002 | 53.1 | 23 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 880 | Q4R4S4 | 186 | ARL8B_MACFA ADP-ribosylation factor-like prot... | 167 | 0.0000002 | 52.4 | 25 | 53 | GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 881 | O95057 | 198 | DIRA1_HUMAN GTP-binding protein Di-Ras1 OS=Ho... | 162 | 0.0000002 | 52.4 | 27 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 882 | Q2HJ68 | 232 | RND1_BOVIN Rho-related GTP-binding protein Rh... | 138 | 0.0000003 | 52.8 | 25 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 883 | P55041 | 295 | GEM_MOUSE GTP-binding protein GEM OS=Mus musc... | 170 | 0.0000003 | 53.1 | 26 | 47 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 884 | Q4P0I7 | 189 | SAR1_USTMA Small COPII coat GTPase SAR1 OS=Us... | 179 | 0.0000004 | 51.6 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 885 | P55040 | 296 | GEM_HUMAN GTP-binding protein GEM OS=Homo sap... | 170 | 0.0000004 | 52.8 | 26 | 47 | GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019003; F:GDP binding; IDA:BHF-UCL.::GO:0005525; F:GTP binding; IDA:BHF-UCL.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0000287; F:magnesium ion binding; IDA:BHF-UCL. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 886 | Q9VHV5 | 186 | ARL8_DROME ADP-ribosylation factor-like prote... | 123 | 0.0000004 | 51.6 | 26 | 56 | GO:0032419; C:extrinsic to lysosome membrane; IDA:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000819; P:sister chromatid segregation; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 887 | Q0VC18 | 200 | ARL4D_BOVIN ADP-ribosylation factor-like prot... | 182 | 0.0000005 | 51.6 | 27 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 888 | Q9NYS0 | 192 | KBRS1_HUMAN NF-kappa-B inhibitor-interacting ... | 141 | 0.0000006 | 51.2 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 889 | O35929 | 297 | REM1_MOUSE GTP-binding protein REM 1 OS=Mus m... | 189 | 0.0000006 | 52.4 | 26 | 43 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 890 | Q91Z61 | 198 | DIRA1_MOUSE GTP-binding protein Di-Ras1 OS=Mu... | 152 | 0.0000006 | 51.2 | 28 | 47 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 891 | Q9BH04 | 192 | KBRS1_MACFA NF-kappa-B inhibitor-interacting ... | 141 | 0.0000007 | 51.2 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 892 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 151 | 0.0000009 | 52.4 | 27 | 48 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 893 | Q8CGU4 | 1186 | AGAP2_RAT Arf-GAP with GTPase, ANK repeat and... | 183 | 0.0000009 | 52.4 | 25 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 894 | P0CR30 | 189 | SAR1_CRYNJ Small COPII coat GTPase SAR1 OS=AT... | 180 | 0.000001 | 50.4 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 895 | P0CR31 | 189 | SAR1_CRYNB Small COPII coat GTPase SAR1 OS=(F... | 180 | 0.000001 | 50.4 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 896 | Q5R541 | 296 | GEM_PONAB GTP-binding protein GEM OS=Pongo ab... | 170 | 0.000001 | 51.2 | 26 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 897 | Q3UHD9 | 1186 | AGAP2_MOUSE Arf-GAP with GTPase, ANK repeat a... | 182 | 0.000002 | 51.6 | 25 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:MGI.::GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 898 | P40617 | 200 | ARL4A_HUMAN ADP-ribosylation factor-like prot... | 123 | 0.000002 | 50.1 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 899 | P61214 | 200 | ARL4A_RAT ADP-ribosylation factor-like protei... | 123 | 0.000002 | 50.1 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 900 | P61213 | 200 | ARL4A_MOUSE ADP-ribosylation factor-like prot... | 123 | 0.000002 | 50.1 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:MGI. | | | | | | | | | | GO:0050873; P:brown fat cell differentiation; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 901 | Q3T0M9 | 200 | ARL4A_BOVIN ADP-ribosylation factor-like prot... | 123 | 0.000002 | 50.1 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |