Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML001W
Length:
208
Number of sequences:
5887
Description:
YML001W YPT7 SGDID:S000004460, Chr XIII from 267174-267800, Genome Release 64-1-1, Verified ORF, "Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661Q9NZQ0    273   DJC27_HUMAN DnaJ homolog subfamily C member 2...1662e-16     79     31     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
662P08642    189   RASH_CHICK GTPase HRas OS=Gallus gallus (Chic...1592e-16     78.2     31     52GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
663Q0VCN3    186   IFT27_BOVIN Intraflagellar transport protein ...1842e-16     78.2     32     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
664Q05147    187   RASK_XENLA GTPase KRas OS=Xenopus laevis (Afr...1542e-16     77.8     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
665P40793    191   CDC42_DROME Cdc42 homolog OS=Drosophila melan...1872e-16     77.8     28     49GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IMP:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030041; P:actin filament polymerization; IMP:FlyBase.::GO:0060446; P:branching involved in open tracheal system development; IMP:FlyBase.::GO:0030031; P:cell projection assembly; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0045200; P:establishment of neuroblast polarity; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035318; P:imaginal disc-derived wing hair outgrowth; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030011; P:maintenance of cell polarity; IMP:FlyBase.::GO:0045185; P:maintenance of protein location; IMP:UniProtKB.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IGI:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IDA:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007396; P:suture of dorsal opening; TAS:FlyBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:FlyBase.::GO:0042060; P:wound healing; IMP:FlyBase.
666Q24816    194   RACC_ENTHI Rho-related protein racC OS=Entamo...1872e-16     77.8     25     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
667Q29HY3    191   CDC42_DROPS Cdc42 homolog OS=Drosophila pseud...1872e-16     77.8     28     49GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
668Q8J212    208   RHO1_KLULA GTP-binding protein Rho1 OS=1267 /...1853e-16     77.8     29     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
669Q5BJQ5    217   RIT2_RAT GTP-binding protein Rit2 OS=Rattus n...1653e-16     77.8     28     53GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
670P70425    217   RIT2_MOUSE GTP-binding protein Rit2 OS=Mus mu...1653e-16     77.8     28     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
671Q17031    191   CDC42_ANOGA Cdc42 homolog OS=Anopheles gambia...1873e-16     77.4     28     49GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
672P22981    184   LET60_CAEEL Ras protein let-60 OS=Caenorhabdi...1543e-16     77.4     32     54GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0048477; P:oogenesis; IGI:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0042659; P:regulation of cell fate specification; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0040025; P:vulval development; IMP:WormBase.
673P48554    192   RAC2_DROME Ras-related protein Rac2 OS=Drosop...1813e-16     77.4     27     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0034334; P:adherens junction maintenance; IGI:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0035010; P:encapsulation of foreign target; IMP:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0002433; P:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; IDA:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IGI:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007426; P:tracheal outgrowth, open tracheal system; IGI:FlyBase.
674Q7ZYF1    273   DJ27A_XENLA DnaJ homolog subfamily C member 2...1723e-16     78.2     29     53
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
675Q16YG0    191   CDC42_AEDAE Cdc42 homolog OS=Aedes aegypti (Y...1874e-16     77.4     28     49GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
676Q59XU5    291   RAS1_CANAL Ras-like protein 1 OS=Candida albi...1664e-16     78.2     32     52GO:0005886; C:plasma membrane; IDA:CGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:CGD.
GO:0044413; P:avoidance of host defenses; IMP:CGD.::GO:0019933; P:cAMP-mediated signaling; IMP:CGD.::GO:0071333; P:cellular response to glucose stimulus; IMP:CGD.::GO:0034605; P:cellular response to heat; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:CGD.::GO:0045595; P:regulation of cell differentiation; IMP:CGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
677Q04970    189   RASN_RAT GTPase NRas OS=Rattus norvegicus (Ra...1694e-16     77     31     50GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
678Q8CFP6    273   DJC27_MOUSE DnaJ homolog subfamily C member 2...1664e-16     77.8     31     52GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
679Q5RD87    189   RASN_PONAB GTPase NRas OS=Pongo abelii (Sumat...1584e-16     77     32     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
680P34144    194   RAC1A_DICDI Rho-related protein rac1A OS=Dict...1814e-16     77     29     46GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
681C4YKT4    288   RAS1_CANAW Ras-like protein 1 OS=Candida albi...1664e-16     77.8     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
682P0CY32    290   RAS1_CANAX Ras-like protein 1 OS=Candida albi...1664e-16     77.8     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
683Q96D21    266   RHES_HUMAN GTP-binding protein Rhes OS=Homo s...2064e-16     77.8     28     45GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031681; F:G-protein beta-subunit binding; IPI:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IC:UniProtKB.
684Q01112    192   CDC42_SCHPO Cell division control protein 42 ...1825e-16     77     30     49GO:0071521; C:Cdc42 GTPase complex; NAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0009898; C:internal side of plasma membrane; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032488; P:Cdc42 protein signal transduction; IC:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0032951; P:regulation of beta-glucan biosynthetic process; IGI:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
685O94363    185   RHB1_SCHPO GTP-binding protein rhb1 OS=Schizo...1635e-16     76.6     34     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:PomBase.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0010963; P:regulation of L-arginine import; IGI:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
686Q54HZ7    189   RACM_DICDI Rho-related protein racM OS=Dictyo...1746e-16     76.6     30     52GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
687P08556    189   RASN_MOUSE GTPase NRas OS=Mus musculus (Mouse...1586e-16     76.6     32     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
688P12825    189   RASN_CAVPO GTPase NRas OS=Cavia porcellus (Gu...1586e-16     76.6     32     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
689Q95ME4    189   RASN_MONDO GTPase NRas OS=Monodelphis domesti...1587e-16     76.6     32     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
690Q2MJK3    189   RASN_PIG GTPase NRas OS=Sus scrofa (Pig). GN=...1587e-16     76.3     32     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
691P01111    189   RASN_HUMAN GTPase NRas OS=Homo sapiens (Human...1587e-16     76.3     32     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
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