Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YML001W
Length:
208
Number of sequences:
5887
Description:
YML001W YPT7 SGDID:S000004460, Chr XIII from 267174-267800, Genome Release 64-1-1, Verified ORF, "Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631P62998    192   RAC1_BOVIN Ras-related C3 botulinum toxin sub...1816e-17     79.3     28     49GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
632Q9NX57    234   RAB20_HUMAN Ras-related protein Rab-20 OS=Hom...2018e-17     79.7     30     45GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
633P01120    322   RAS2_YEAST Ras-like protein 2 OS=Saccharomyce...1548e-17     80.5     33     55GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:SGD.::GO:0030437; P:ascospore formation; IMP:SGD.::GO:0000411; P:positive regulation of transcription by galactose; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; TAS:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
634Q6IMM1    273   DJC27_CHICK DnaJ homolog subfamily C member 2...1729e-17     79.7     31     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
635Q5F352    189   RASN_CHICK GTPase NRas OS=Gallus gallus (Chic...1691e-16     79     31     50GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
636B4NJ72    189   RAS1_DROWI Ras-like protein 1 OS=Drosophila w...1541e-16     79     33     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
637B4JFU8    189   RAS1_DROGR Ras-like protein 1 OS=Drosophila g...1541e-16     79     33     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
638P10114    183   RAP2A_HUMAN Ras-related protein Rap-2a OS=Hom...1781e-16     78.6     34     52GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0034613; P:cellular protein localization; IDA:UniProtKB.::GO:0045184; P:establishment of protein localization; IDA:MGI.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
639Q6IML7    273   DJC27_RAT DnaJ homolog subfamily C member 27 ...1661e-16     79.7     31     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
640B4PUP5    189   RAS1_DROYA Ras-like protein 1 OS=Drosophila y...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
641P83831    189   RAS1_DROSI Ras-like protein 1 OS=Drosophila s...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
642B4HKC7    189   RAS1_DROSE Ras-like protein 1 OS=Drosophila s...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
643P08646    189   RAS1_DROME Ras-like protein 1 OS=Drosophila m...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005525; F:GTP binding; NAS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0006916; P:anti-apoptosis; NAS:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0001708; P:cell fate specification; TAS:FlyBase.::GO:0016049; P:cell growth; TAS:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IMP:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:FlyBase.::GO:0007369; P:gastrulation; IMP:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0046673; P:negative regulation of compound eye retinal cell programmed cell death; IMP:FlyBase.::GO:0007309; P:oocyte axis specification; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; TAS:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0046534; P:positive regulation of photoreceptor cell differentiation; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0006606; P:protein import into nucleus; IGI:FlyBase.::GO:0008361; P:regulation of cell size; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0040014; P:regulation of multicellular organism growth; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; TAS:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048865; P:stem cell fate commitment; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; IMP:FlyBase.
644P83832    189   RAS1_DROMA Ras-like protein 1 OS=Drosophila m...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
645B3NZR4    189   RAS1_DROER Ras-like protein 1 OS=Drosophila e...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
646B3M185    189   RAS1_DROAN Ras-like protein 1 OS=Drosophila a...1541e-16     78.6     33     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
647Q07983    188   RASK_MONDO GTPase KRas OS=Monodelphis domesti...1541e-16     78.6     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
648B4LY29    189   RAS1_DROVI Ras-like protein 1 OS=Drosophila v...1541e-16     78.6     33     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
649Q6IMK3    273   DJC27_DANRE DnaJ homolog subfamily C member 2...1661e-16     79.3     32     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
650Q9BW83    186   IFT27_HUMAN Intraflagellar transport protein ...1841e-16     78.6     33     48GO:0030992; C:intraflagellar transport particle B; ISS:BHF-UCL.::GO:0009434; C:microtubule-based flagellum; ISS:BHF-UCL.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
651P20171    189   RASH_RAT GTPase HRas OS=Rattus norvegicus (Ra...1591e-16     78.6     31     52GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:RGD.::GO:0007265; P:Ras protein signal transduction; IMP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
652Q61411    189   RASH_MOUSE GTPase HRas OS=Mus musculus (Mouse...1591e-16     78.6     31     52GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IPI:MGI.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0007265; P:Ras protein signal transduction; TAS:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
653P01112    189   RASH_HUMAN GTPase HRas OS=Homo sapiens (Human...1591e-16     78.6     31     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0090398; P:cellular senescence; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
654P22126    213   RAS1_NEUCR Protein ras-1 OS=1257 / FGSC 987)....1611e-16     79     30     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
655P04388    192   RAS2_DROME Ras-like protein 2 OS=Drosophila m...1721e-16     78.6     31     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
656Q5RDE5    273   DJC27_PONAB DnaJ homolog subfamily C member 2...1662e-16     79.3     31     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
657Q295X7    189   RAS1_DROPS Ras-like protein 1 OS=Drosophila p...1542e-16     78.2     33     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
658B4GFJ8    189   RAS1_DROPE Ras-like protein 1 OS=Drosophila p...1542e-16     78.2     33     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
659P60764    192   RAC3_MOUSE Ras-related C3 botulinum toxin sub...1812e-16     78.2     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0030031; P:cell projection assembly; ISS:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
660P60763    192   RAC3_HUMAN Ras-related C3 botulinum toxin sub...1812e-16     78.2     28     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0031941; C:filamentous actin; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0030031; P:cell projection assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
661Q9NZQ0    273   DJC27_HUMAN DnaJ homolog subfamily C member 2...1662e-16     79     31     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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