Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR446W
Length:
433
Number of sequences:
5887
Description:
YLR446W YLR446W SGDID:S000004438, Chr XII from 1025214-1026515, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function with similarity to hexokinases; transcript is upregulated during sporulation and the unfolded protein response; YLR446W is not an essential gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q2KNB5    504   HXK10_ORYSJ Hexokinase-10 OS=Oryza sativa sub...2900.002     44.3     24     39GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
32Q6Q8A5    499   HXK2_TOBAC Hexokinase-2, chloroplastic OS=Nic...1890.002     43.9     25     40GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
33Q8LQ68    506   HXK6_ORYSJ Hexokinase-6 OS=Oryza sativa subsp...1150.003     43.5     24     46GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
34Q5W676    507   HXK5_ORYSJ Hexokinase-5 OS=Oryza sativa subsp...1920.003     43.5     24     43GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
35Q26609    451   HXK_SCHMA Hexokinase OS=Schistosoma mansoni (...2240.003     43.1     25     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
36Q9SEK3    498   HXK1_SPIOL Hexokinase-1 OS=Spinacia oleracea ...940.004     43.1     27     48GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
37Q92407    495   HXKG_ASPNG Glucokinase OS=Aspergillus niger. ...1590.007     42.4     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
38Q1WM16    463   HXK7_ORYSJ Hexokinase-7 OS=Oryza sativa subsp...2620.012     41.6     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
39Q9SEK2    497   HXK1_TOBAC Hexokinase-1 OS=Nicotiana tabacum ...940.016     41.2     26     48GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
40P33284    485   HXK_KLULA Hexokinase OS=1267 / NRRL Y-1140 / ...4360.017     40.8     23     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
41P17712    465   HXK4_RAT Glucokinase OS=Rattus norvegicus (Ra...2530.018     40.8     23     43GO:0044448; C:cell cortex part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IPI:RGD.
GO:0001678; P:cellular glucose homeostasis; IMP:RGD.::GO:0042149; P:cellular response to glucose starvation; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IDA:RGD.::GO:0005978; P:glycogen biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:RGD.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:RGD.::GO:0019932; P:second-messenger-mediated signaling; IDA:RGD.
42O64390    498   HXK1_SOLTU Hexokinase-1 OS=Solanum tuberosum ...840.022     40.8     25     50GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
43P52792    465   HXK4_MOUSE Glucokinase OS=Mus musculus (Mouse...2530.023     40.4     23     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.
GO:0070509; P:calcium ion import; IMP:UniProtKB.::GO:0001678; P:cellular glucose homeostasis; IMP:MGI.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006739; P:NADP metabolic process; IMP:MGI.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0043266; P:regulation of potassium ion transport; IMP:MGI.
44Q1WM15    458   HXK8_ORYSJ Hexokinase-8 OS=Oryza sativa subsp...1840.023     40.4     23     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
45P50521    455   HXK2_SCHPO Hexokinase-2 OS=Schizosaccharomyce...2200.025     40.4     23     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase.
GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006013; P:mannose metabolic process; IDA:PomBase.
46P35557    465   HXK4_HUMAN Glucokinase OS=Homo sapiens (Human...2310.026     40.4     23     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004340; F:glucokinase activity; IDA:UniProtKB.::GO:0005536; F:glucose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.::GO:0051594; P:detection of glucose; IMP:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0006110; P:regulation of glycolysis; NAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome.
47P80581    490   HXK_EMENI Hexokinase OS=194 / M139) (Aspergil...2580.026     40.4     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
48Q9LPS1    498   HXK3_ARATH Hexokinase-3 OS=Arabidopsis thalia...2190.061     39.3     21     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0009536; C:plastid; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
49P50506    478   HXK_SCHOC Hexokinase OS=Schwanniomyces occide...2290.064     39.3     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
50Q42525    496   HXK1_ARATH Hexokinase-1 OS=Arabidopsis thalia...1900.066     39.3     23     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009536; C:plastid; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:TAIR.::GO:0004340; F:glucokinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IDA:TAIR.
GO:0010255; P:glucose mediated signaling pathway; IMP:TAIR.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0012501; P:programmed cell death; IMP:TAIR.
51Q02155    493   HXK_PLAFA Hexokinase OS=Plasmodium falciparum...1170.15     38.1     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
52P04806    485   HXKA_YEAST Hexokinase-1 OS=Saccharomyces cere...2180.24     37.4     21     42GO:0005829; C:cytosol; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:SGD.
GO:0032445; P:fructose import; IGI:SGD.::GO:0006000; P:fructose metabolic process; IMP:SGD.::GO:0006096; P:glycolysis; IDA:SGD.::GO:0006013; P:mannose metabolic process; IDA:SGD.
53Q8LH82    498   HXK1_ORYSJ Hexokinase-1 OS=Oryza sativa subsp...940.3     37     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
54A6Q2V4    294   DAPA_NITSB Dihydrodipicolinate synthase OS=Ni...1150.43     36.2     29     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008840; F:dihydrodipicolinate synthase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
55P83776    484   HXKB_CANAL Hexokinase-2 OS=Candida albicans (...3230.57     36.2     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
56P04807    486   HXKB_YEAST Hexokinase-2 OS=Saccharomyces cere...2260.92     35.4     23     39GO:0005829; C:cytosol; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:SGD.
GO:0032445; P:fructose import; IGI:SGD.::GO:0006000; P:fructose metabolic process; IMP:SGD.::GO:0006096; P:glycolysis; IDA:SGD.::GO:0006013; P:mannose metabolic process; IDA:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0046015; P:regulation of transcription by glucose; IDA:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
57Q969A8    468   HXK_TOXGO Hexokinase OS=Toxoplasma gondii. GN...3340.92     35.4     22     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
58Q56XE8    502   HXK4_ARATH Hexokinase-4 OS=Arabidopsis thalia...1051.7     34.7     24     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
59Q1K8F6    653   NAGS_NEUCR Amino-acid acetyltransferase, mito...752.1     34.7     35     49GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004042; F:acetyl-CoA:L-glutamate N-acetyltransferase activity; IEA:EC.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
60A1XGU4    738   NU5C_RANMC NAD(P)H-quinone oxidoreductase sub...593.1     33.9     32     49GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.::GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
records
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