Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR442C
Length:
978
Number of sequences:
5887
Description:
YLR442C SIR3 SGDID:S000004434, Chr XII from 1022251-1019315, Genome Release 64-1-1, reverse complement, Verified ORF, "Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P06701    978   SIR3_YEAST Regulatory protein SIR3 OS=Sacchar...9780     1999     100     100GO:0005677; C:chromatin silencing complex; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000783; C:nuclear telomere cap complex; IDA:SGD.::GO:0005724; C:nuclear telomeric heterochromatin; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.
GO:0003690; F:double-stranded DNA binding; IDA:SGD.::GO:0031493; F:nucleosomal histone binding; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IPI:SGD.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.::GO:0030527; F:structural constituent of chromatin; TAS:SGD.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IDA:SGD.::GO:0031507; P:heterochromatin assembly; IMP:SGD.::GO:0001308; P:negative regulation of chromatin silencing involved in replicative cell aging; IDA:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2P54784    914   ORC1_YEAST Origin recognition complex subunit...4081e-33     143     28     47GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0005664; C:nuclear origin of replication recognition complex; IMP:SGD.::GO:0005656; C:pre-replicative complex; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IMP:SGD.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IDA:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.
3P54788    886   ORC1_KLULA Origin recognition complex subunit...4631e-29     130     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
4O74270    805   ORC1_CANAX Origin recognition complex subunit...1905.4     34.7     26     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
5Q6BSE2    810   ORC1_DEBHA Origin recognition complex subunit...2270.000000004     64.3     25     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
6P54789    707   ORC1_SCHPO Origin recognition complex subunit...3490.000002     55.5     19     41GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0003688; F:DNA replication origin binding; IDA:UniProtKB.
GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:PomBase.
7Q9JI69    850   ORC1_CRIGR Origin recognition complex subunit...3490.000006     53.9     19     40GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
8Q8I615    1189   ORC1_PLAF7 Origin recognition complex subunit...3540.00001     53.5     23     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
9P41411    577   CDC18_SCHPO Cell division control protein 18 ...3040.00007     50.4     23     44GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003689; F:DNA clamp loader activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0006267; P:pre-replicative complex assembly; ISS:PomBase.
10Q13415    861   ORC1_HUMAN Origin recognition complex subunit...3610.00007     50.4     19     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0006270; P:DNA-dependent DNA replication initiation; TAS:ProtInc.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
11Q80Z32    848   ORC1_RAT Origin recognition complex subunit 1...3500.0001     49.7     19     41GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
12Q58DC8    863   ORC1_BOVIN Origin recognition complex subunit...3630.0002     48.9     20     42GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13O16810    924   ORC1_DROME Origin recognition complex subunit...3330.0003     48.1     18     38GO:0005664; C:nuclear origin of replication recognition complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0006277; P:DNA amplification; IMP:FlyBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:FlyBase.
14Q9Z1N2    840   ORC1_MOUSE Origin recognition complex subunit...3070.001     47     18     41GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; TAS:MGI.
15O26115    153   RL22_METTH 50S ribosomal protein L22P OS=ther...1050.9     35.4     26     52GO:0015934; C:large ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
16Q037Z6    657   SYT_LACC3 Threonine--tRNA ligase OS=Lactobaci...575.1     34.7     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004829; F:threonine-tRNA ligase activity; IEA:EC.
GO:0006435; P:threonyl-tRNA aminoacylation; IEA:InterPro.
records
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