Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR426W
Length:
326
Number of sequences:
5887
Description:
YLR426W TDA5 SGDID:S000004418, Chr XII from 987062-987141,987213-988113, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06417    326   TDA5_YEAST Uncharacterized oxidoreductase TDA...3260     667     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042493; P:response to drug; IMP:SGD.
2Q07530    308   YD114_YEAST Uncharacterized oxidoreductase YD...2611e-28     116     31     50
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
3Q1MTR7    286   YBPE_SCHPO Uncharacterized oxidoreductase C16...2531e-24     105     30     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; ISS:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
4O18404    255   HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase ty...2740.00000000000004     73.9     28     44GO:0005829; C:cytosol; NAS:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0047022; F:7-beta-hydroxysteroid dehydrogenase (NADP+) activity; IDA:FlyBase.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:FlyBase.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:FlyBase.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:FlyBase.
GO:0006637; P:acyl-CoA metabolic process; IDA:FlyBase.::GO:0008209; P:androgen metabolic process; IDA:FlyBase.::GO:0008205; P:ecdysone metabolic process; IDA:FlyBase.::GO:0008210; P:estrogen metabolic process; IDA:FlyBase.::GO:0006631; P:fatty acid metabolic process; IDA:FlyBase.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
5Q6NRV4    341   RD10B_XENLA Retinol dehydrogenase 10-B OS=Xen...2230.0000000000001     74.3     28     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
6Q7T2D1    336   RD10B_DANRE Retinol dehydrogenase 10-B OS=Dan...2330.0000000000003     72.8     26     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
7P0A2C9    244   FABG_SALTY 3-oxoacyl-[acyl-carrier-protein] r...1940.0000000000004     71.2     27     51
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; IMP:UniProtKB.]
8P0A2D0    244   FABG_SALTI 3-oxoacyl-[acyl-carrier-protein] r...1940.0000000000004     71.2     27     51
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
9Q7TQA3    309   RDHE2_MOUSE Epidermal retinol dehydrogenase 2...2310.0000000000005     72     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.
10Q9X248    246   FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] r...1900.0000000000008     70.5     27     49
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
11Q6AYS8    298   DHB11_RAT Estradiol 17-beta-dehydrogenase 11 ...2300.000000000001     70.9     26     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
12Q5XGF7    341   RDH10_XENTR Retinol dehydrogenase 10 OS=Xenop...2200.000000000001     71.2     25     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
13Q6DCT3    341   RD10A_XENLA Retinol dehydrogenase 10-A OS=Xen...2200.000000000002     70.9     25     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
14P0AEK3    244   FABG_SHIFL 3-oxoacyl-[acyl-carrier-protein] r...1920.000000000002     69.3     28     49
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
15P0AEK2    244   FABG_ECOLI 3-oxoacyl-[acyl-carrier-protein] r...1920.000000000002     69.3     28     49
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IMP:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; IDA:UniProtKB.
GO:0009102; P:biotin biosynthetic process; IMP:EcoCyc.::GO:0030497; P:fatty acid elongation; IMP:UniProtKB.]
16Q80ZF7    341   RDH10_RAT Retinol dehydrogenase 10 OS=Rattus ...1490.000000000003     70.1     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
17Q8IZV5    341   RDH10_HUMAN Retinol dehydrogenase 10 OS=Homo ...1490.000000000003     70.1     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB.::GO:0007601; P:visual perception; IDA:MGI.
18Q8HZT6    341   RDH10_BOVIN Retinol dehydrogenase 10 OS=Bos t...1490.000000000003     70.1     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:MGI.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
19Q8VCH7    341   RDH10_MOUSE Retinol dehydrogenase 10 OS=Mus m...1490.000000000003     70.1     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IMP:MGI.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IMP:MGI.
GO:0060449; P:bud elongation involved in lung branching; IMP:MGI.::GO:0043583; P:ear development; IMP:MGI.::GO:0031076; P:embryonic camera-type eye development; IMP:MGI.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0048703; P:embryonic viscerocranium morphogenesis; IMP:MGI.::GO:0008406; P:gonad development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001656; P:metanephros development; IMP:MGI.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0043584; P:nose development; IMP:MGI.::GO:0060431; P:primary lung bud formation; IMP:MGI.::GO:0002138; P:retinoic acid biosynthetic process; IMP:MGI.
20Q7Z5P4    300   DHB13_HUMAN 17-beta-hydroxysteroid dehydrogen...2090.000000000004     69.3     28     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
21Q53217    548   Y4VI_RHISN Uncharacterized short-chain type d...2642.8     33.5     20     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
22P39333    237   YJGI_ECOLI Uncharacterized oxidoreductase yjg...2020.000000000006     67.8     28     47
GO:0035438; F:cyclic-di-GMP binding; IDA:EcoCyc.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0044010; P:single-species biofilm formation; IMP:EcoCyc.
23Q4A054    234   Y0419_STAS1 Uncharacterized oxidoreductase SS...1940.000000000009     67.4     27     47
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
24Q8N3Y7    309   RDHE2_HUMAN Epidermal retinol dehydrogenase 2...2170.00000000001     68.2     27     45GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
GO:0050908; P:detection of light stimulus involved in visual perception; NAS:UniProtKB.::GO:0043616; P:keratinocyte proliferation; IMP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB.
25Q5M875    300   DHB13_RAT 17-beta-hydroxysteroid dehydrogenas...2580.00000000001     68.2     25     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
26Q5NVG2    300   DHB11_PONAB Estradiol 17-beta-dehydrogenase 1...2090.00000000001     67.8     26     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
27P37079    267   SORD_KLEPN Sorbitol-6-phosphate 2-dehydrogena...2050.00000000001     67.4     28     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0009010; F:sorbitol-6-phosphate 2-dehydrogenase activity; IEA:EC.
28Q8NBQ5    300   DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1...2090.00000000002     67.4     26     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
29P07914    249   BAIA1_EUBSP Bile acid 7-dehydroxylase 1/3 OS=...2050.00000000002     66.2     24     44
GO:0033792; F:bile-acid 7alpha-dehydroxylase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
30Q9N126    312   RDH8_BOVIN Retinol dehydrogenase 8 OS=Bos tau...1940.00000000002     67     29     46GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
31Q8VID1    279   DHRS4_RAT Dehydrogenase/reductase SDR family ...2100.00000000003     66.6     24     47GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IDA:RGD.
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
records
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