Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR426W
Length:
326
Number of sequences:
5887
Description:
YLR426W TDA5 SGDID:S000004418, Chr XII from 987062-987141,987213-988113, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q7Z4W1    244   DCXR_HUMAN L-xylulose reductase OS=Homo sapie...1920.027     39.3     26     41GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
392Q09517    316   LE767_CAEEL Putative steroid dehydrogenase le...2490.028     39.3     23     41GO:0045179; C:apical cortex; IDA:WormBase.::GO:0005783; C:endoplasmic reticulum; IDA:WormBase.
GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008209; P:androgen metabolic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008210; P:estrogen metabolic process; IMP:WormBase.::GO:0030540; P:female genitalia development; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0032350; P:regulation of hormone metabolic process; IMP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IDA:WormBase.
393P69936    248   YDFG_SALTY NADP-dependent L-serine/L-allo-thr...1990.029     39.3     20     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
394P69935    248   YDFG_SALTI NADP-dependent L-serine/L-allo-thr...1990.029     39.3     20     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
395O32184    129   YUSR_BACSU Short-chain dehydrogenase/reductas...720.03     37.7     33     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
396P51657    344   DHB1_RAT Estradiol 17-beta-dehydrogenase 1 OS...1870.032     39.3     26     40GO:0005829; C:cytosol; IDA:RGD.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.
GO:0060348; P:bone development; IEP:RGD.::GO:0071248; P:cellular response to metal ion; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IDA:RGD.::GO:0061370; P:testosterone biosynthetic process; IDA:RGD.
397P40398    299   YHXD_BACSU Uncharacterized oxidoreductase yhx...2180.032     39.3     22     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
398P0CR34    361   MKAR_CRYNJ 3-ketoacyl-CoA reductase OS=ATCC M...1850.033     39.3     22     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
399P0CR35    361   MKAR_CRYNB 3-ketoacyl-CoA reductase OS=(Filob...1850.033     39.3     22     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
400P27874    430   MAS11_AGRRH Agropine synthesis reductase OS=A...1750.036     39.3     25     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0052007; P:biosynthesis by symbiont of substance in host; IEA:InterPro.
401Q60V51    316   LE767_CAEBR Putative steroid dehydrogenase le...2470.038     38.9     23     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030540; P:female genitalia development; ISS:UniProtKB.::GO:0042303; P:molting cycle; ISS:UniProtKB.::GO:0032350; P:regulation of hormone metabolic process; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
402Q8K354    277   CBR3_MOUSE Carbonyl reductase [NADPH] 3 OS=Mu...1420.039     38.9     26     46
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.
403P35731    278   FABG_YEAST 3-oxoacyl-[acyl-carrier-protein] r...2310.039     38.9     25     39GO:0005739; C:mitochondrion; IMP:SGD.
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009060; P:aerobic respiration; IMP:SGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
404P0CR37    335   TSC10_CRYNB 3-ketodihydrosphingosine reductas...1720.044     38.9     19     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
405O17795    315   STDH2_CAEEL Putative steroid dehydrogenase 2 ...2120.046     38.9     25     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
406Q10130    378   DHS5_CAEEL Uncharacterized oxidoreductase dhs...2080.046     38.9     23     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
407P0CR36    335   TSC10_CRYNJ 3-ketodihydrosphingosine reductas...1720.047     38.9     19     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
408Q91XV4    244   DCXR_MESAU L-xylulose reductase OS=Mesocricet...1910.053     38.1     27     42GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
409Q9KWN1    249   SDH_RHIRD Serine 3-dehydrogenase OS=radiobact...1950.059     38.1     22     39
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC.
410Q8JZV9    245   BDH2_MOUSE 3-hydroxybutyrate dehydrogenase ty...1860.063     38.1     22     46GO:0005737; C:cytoplasm; ISS:HGNC.
GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; ISS:HGNC.::GO:0051287; F:NAD binding; ISS:HGNC.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IMP:UniProtKB.
GO:0006635; P:fatty acid beta-oxidation; ISS:HGNC.::GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; IMP:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; IMP:UniProtKB.
411P51659    736   DHB4_HUMAN Peroxisomal multifunctional enzyme...1800.069     38.5     24     42GO:0005782; C:peroxisomal matrix; TAS:Reactome.
GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.::GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016508; F:long-chain-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.
GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.::GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
412Q8MI29    277   CBR1_MACFA Carbonyl reductase [NADPH] 1 OS=Ma...1510.069     38.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB.
413Q7FAE1    274   MOMAS_ORYSJ Momilactone A synthase OS=Oryza s...1800.069     38.1     23     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
414Q2KIJ5    331   KDSR_BOVIN 3-ketodihydrosphingosine reductase...2000.069     38.1     22     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
415Q9Y7P2    503   YCKF_SCHPO Uncharacterized protein C1450.15 O...530.071     38.5     34     66GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; ISS:PomBase.::GO:0000234; F:phosphoethanolamine N-methyltransferase activity; ISS:PomBase.
GO:0006666; P:3-keto-sphinganine metabolic process; ISS:PomBase.::GO:0006506; P:GPI anchor biosynthetic process; ISS:PomBase.
416O05919    263   Y927C_MYCTU Uncharacterized oxidoreductase Rv...2110.071     38.1     25     40GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
417Q8CHS7    311   DRS7C_MOUSE Dehydrogenase/reductase SDR famil...1230.073     38.1     31     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
418P51656    344   DHB1_MOUSE Estradiol 17-beta-dehydrogenase 1 ...1870.074     38.1     25     40
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
419Q8BYK4    316   RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m...2390.083     38.1     21     39GO:0005622; C:intracellular; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
420Q11177    816   DHS27_CAEEL Uncharacterized oxidoreductase dh...1440.087     38.5     22     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
421Q758B6    307   TSC10_ASHGO 3-ketodihydrosphingosine reductas...2410.087     37.7     21     35GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
records
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