Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR426W
Length:
326
Number of sequences:
5887
Description:
YLR426W TDA5 SGDID:S000004418, Chr XII from 987062-987141,987213-988113, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301P27582    201   FABG6_BRANA 3-oxoacyl-[acyl-carrier-protein] ...1240.0006     43.9     30     47GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
302P19871    254   3BHD_COMTE 3-beta-hydroxysteroid dehydrogenas...1970.0006     44.3     23     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; IEA:EC.
GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.]
303Q8FHD2    248   YDFG_ECOL6 NADP-dependent L-serine/L-allo-thr...1990.0006     44.3     23     40
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
304P80869    258   DHG2_BACSU Glucose 1-dehydrogenase 2 OS=Bacil...2080.0007     44.3     23     44
GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.]
305Q1RMJ5    311   DRS7C_BOVIN Dehydrogenase/reductase SDR famil...1200.0007     44.3     32     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
306Q8BTX9    330   HSDL1_MOUSE Inactive hydroxysteroid dehydroge...1730.0008     44.3     22     45GO:0005739; C:mitochondrion; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
307Q9CXR1    338   DHRS7_MOUSE Dehydrogenase/reductase SDR famil...1920.0008     44.3     24     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
308Q09851    296   AYR1_SCHPO NADPH-dependent 1-acyldihydroxyace...1730.0008     44.3     25     51GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.
GO:0000140; F:acylglycerone-phosphate reductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006654; P:phosphatidic acid biosynthetic process; ISS:PomBase.
309P16542    272   DHK1_STRVN Granaticin polyketide synthase put...2100.0008     43.9     23     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
310O77769    302   DHRS3_BOVIN Short-chain dehydrogenase/reducta...2370.0009     43.9     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
311O06544    250   Y1144_MYCTU Uncharacterized oxidoreductase Rv...2020.001     43.5     24     43GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
312P19992    255   HSD_STREX 3-alpha-(or 20-beta)-hydroxysteroid...1970.001     43.5     24     44
GO:0047044; F:androstan-3-alpha,17-beta-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
313P12310    261   DHG_BACSU Glucose 1-dehydrogenase OS=Bacillus...2070.001     43.5     23     48
GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.]
314Q9P7B4    259   YI13_SCHPO Uncharacterized oxidoreductase C52...1910.001     43.5     24     45GO:0005829; C:cytosol; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
315P50203    248   PHAB_ACISR Acetoacetyl-CoA reductase OS=Acine...1190.001     43.5     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:InterPro.
316P70720    242   FABG_AGGAC 3-oxoacyl-[acyl-carrier-protein] r...1940.001     43.5     25     43
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
317Q4V8B7    330   HSDL1_RAT Inactive hydroxysteroid dehydrogena...1730.001     43.5     22     46GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
318P50199    256   GNO_GLUOX Gluconate 5-dehydrogenase OS=Glucon...1920.001     43.5     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008874; F:gluconate 5-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
319P37059    387   DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 ...2320.001     43.9     23     40GO:0005789; C:endoplasmic reticulum membrane; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:UniProtKB.
GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
320P39831    248   YDFG_ECOLI NADP-dependent 3-hydroxy acid dehy...1990.001     43.1     23     40
GO:0035527; F:3-hydroxypropionate dehydrogenase (NADP+) activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IDA:EcoCyc.
GO:0006212; P:uracil catabolic process; IMP:EcoCyc.
321P50167    278   ARDH_PICST D-arabinitol 2-dehydrogenase [ribu...2050.001     43.5     24     40
GO:0047038; F:D-arabinitol 2-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; ISS:UniProtKB.
322Q7ZY31    263   SPRE_XENLA Sepiapterin reductase OS=Xenopus l...2050.001     43.1     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB.
GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
323Q8VCC1    269   PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen...1850.001     43.1     21     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
324P87025    272   THR1_GLOLA Trihydroxynaphthalene reductase OS...1930.001     43.1     21     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
325P50166    282   ARDH_CANTR D-arabinitol 2-dehydrogenase [ribu...1990.001     43.1     23     39
GO:0047038; F:D-arabinitol 2-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IDA:UniProtKB.
326Q9BPX1    270   DHB14_HUMAN 17-beta-hydroxysteroid dehydrogen...1390.002     43.1     20     47GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; IDA:HGNC.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:HGNC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IDA:HGNC.
GO:0006706; P:steroid catabolic process; IDA:HGNC.
327O54939    306   DHB3_RAT Testosterone 17-beta-dehydrogenase 3...1910.002     43.1     23     48GO:0005792; C:microsome; IDA:RGD.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.
GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD.
328Q8X505    248   YDFG_ECO57 NADP-dependent L-serine/L-allo-thr...1990.002     43.1     23     40
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
329O75911    302   DHRS3_HUMAN Short-chain dehydrogenase/reducta...2400.002     43.1     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; TAS:ProtInc.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042572; P:retinol metabolic process; TAS:UniProtKB.::GO:0007601; P:visual perception; TAS:ProtInc.
330A0PJE2    317   DHR12_HUMAN Dehydrogenase/reductase SDR famil...1390.002     43.1     22     47
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
331P23238    241   PHBB_ZOORA Acetoacetyl-CoA reductase OS=Zoogl...1870.002     43.1     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW.
records
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