Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR426W
Length:
326
Number of sequences:
5887
Description:
YLR426W TDA5 SGDID:S000004418, Chr XII from 987062-987141,987213-988113, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q92506    261   DHB8_HUMAN Estradiol 17-beta-dehydrogenase 8 ...2020.00001     49.7     25     43GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IDA:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.
GO:0006703; P:estrogen biosynthetic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
212Q9R092    317   H17B6_MOUSE 17-beta-hydroxysteroid dehydrogen...2010.00001     50.1     26     43GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.
GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
213P50201    430   MAS12_AGRRH Agropine synthesis reductase OS=A...2170.00001     50.1     26     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0052007; P:biosynthesis by symbiont of substance in host; IEA:InterPro.
214Q00791    264   STCU_EMENI Versicolorin reductase OS=194 / M1...1990.00001     49.7     25     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
215P51976    406   DHI2_RABIT Corticosteroid 11-beta-dehydrogena...1900.00001     50.1     27     42GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
216Q13268    258   DHRS2_HUMAN Dehydrogenase/reductase SDR famil...1930.00001     49.3     24     45GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB.
GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB.
217P55006    317   RDH7_RAT Retinol dehydrogenase 7 OS=Rattus no...1970.00001     49.7     24     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.
218P39485    261   DHG4_BACME Glucose 1-dehydrogenase 4 OS=Bacil...2110.00001     49.3     25     47
GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.]
219O42866    236   FABG_SCHPO 3-oxoacyl-[acyl-carrier-protein] r...2040.00001     49.3     25     45GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009060; P:aerobic respiration; IC:PomBase.::GO:0009107; P:lipoate biosynthetic process; IC:PomBase.]
220Q00278    271   NOR1_ASPPA Aflatoxin biosynthesis ketoreducta...2000.00001     49.3     24     44
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
221Q56632    262   VIBA_VIBCH Vibriobactin-specific 2,3-dihydro-...1930.00002     49.3     27     44
GO:0008667; F:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009239; P:enterobactin biosynthetic process; IEA:InterPro.
222Q04520    241   BUDC_RAOTE Diacetyl reductase [(S)-acetoin fo...1960.00002     48.9     27     47
GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0045150; P:acetoin catabolic process; IEA:InterPro.
223P66777    592   EPHD_MYCTU Probable oxidoreductase ephD OS=My...2400.00002     50.1     23     41GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005887; C:integral to plasma membrane; IDA:MTBBASE.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
224P66778    592   EPHD_MYCBO Probable oxidoreductase ephD OS=My...2400.00002     50.1     23     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
225Q566S6    309   DRS7B_DANRE Dehydrogenase/reductase SDR famil...2040.00002     48.9     26     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
226Q1DNC5    349   MKAR_COCIM 3-ketoacyl-CoA reductase OS=Coccid...2000.00002     49.3     26     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
227O14756    317   H17B6_HUMAN 17-beta-hydroxysteroid dehydrogen...1950.00002     48.9     26     42GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.
GO:0006702; P:androgen biosynthetic process; NAS:UniProtKB.::GO:0006710; P:androgen catabolic process; TAS:UniProtKB.
228Q29529    244   CBR2_PIG Carbonyl reductase [NADPH] 2 OS=Sus ...1850.00002     48.5     29     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
229Q8MJY8    266   PGDH_MACFA 15-hydroxyprostaglandin dehydrogen...2020.00002     48.9     22     47GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; IEP:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
230P39483    261   DHG2_BACME Glucose 1-dehydrogenase 2 OS=Bacil...2100.00002     48.5     24     48
GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.]
231P15428    266   PGDH_HUMAN 15-hydroxyprostaglandin dehydrogen...2020.00003     48.5     22     47GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IDA:UniProtKB.::GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
232Q12634    283   T4HR_MAGO7 Tetrahydroxynaphthalene reductase ...1940.00003     48.5     22     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047039; F:tetrahydroxynaphthalene reductase activity; IEA:EC.
GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
233Q59V93    349   MKAR_CANAL 3-ketoacyl-CoA reductase OS=Candid...1830.00003     48.5     27     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
234Q3T0C2    266   PGDH_BOVIN 15-hydroxyprostaglandin dehydrogen...2250.00004     48.1     21     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0060206; P:estrous cycle phase; IEP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
235Q01198    305   LIGD_PSEPA C alpha-dehydrogenase OS=Pseudomon...1860.00004     48.1     23     42
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0046274; P:lignin catabolic process; IEA:UniProtKB-KW.
236P72220    277   BPHB_PSEPU Cis-2,3-dihydrobiphenyl-2,3-diol d...1910.00004     48.1     24     47
GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
237Q5R7K0    330   HSDL1_PONAB Inactive hydroxysteroid dehydroge...2290.00004     48.1     24     45GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
238P14697    246   PHBB_CUPNH Acetoacetyl-CoA reductase OS=(Rals...1930.00004     47.8     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW.
239Q5ZJG8    331   HSDL1_CHICK Hydroxysteroid dehydrogenase-like...2060.00004     48.1     24     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
240Q7Z9I3    253   YCP8_SCHPO Uncharacterized oxidoreductase C66...2110.00004     47.8     23     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0033554; P:cellular response to stress; IEP:PomBase.
241Q9FZ42    288   GRDH1_ARATH Glucose and ribitol dehydrogenase...2070.00005     48.1     22     43GO:0009507; C:chloroplast; IDA:TAIR.
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro.
records
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